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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

Nature medicine, 2017-10, Vol.23 (10), p.1150-1157

2017

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Proteopathic tau seeding predicts tauopathy in vivo

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.E4376-E4385

2014

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Peripheral biomarkers of major depression and antidepressant treatment response: Current knowledge and future outlooks

Journal of affective disorders, 2018-06, Vol.233, p.3-14

2018

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A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in Escherichia coli

Biochemistry (Easton), 2013-03, Vol.52 (10), p.1828-1837

2013

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Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

The Journal of neuroscience, 2012-11, Vol.32 (46), p.16129-16140

2012

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Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics

The Journal of biological chemistry, 2019-01, Vol.294 (3), p.1045-1058

2019

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Calcineurin and glial signaling: neuroinflammation and beyond

Journal of neuroinflammation, 2014-09, Vol.11 (1), p.158-158, Article 158

2014

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Widespread tau seeding activity at early Braak stages

Acta neuropathologica, 2017-01, Vol.133 (1), p.91-100

2017

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A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes

Journal of the American Chemical Society, 2014-06, Vol.136 (23), p.8411-8417

2014

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Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury

The Journal of neuroscience, 2016-02, Vol.36 (5), p.1502-1515

2016

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Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

The Journal of neuroscience, 2017-06, Vol.37 (25), p.6132-6148

2017

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Dysfunctional adaptive immune response in adolescents and young adults with suicide behavior

Psychoneuroendocrinology, 2020-01, Vol.111, p.104487-104487, Article 104487

2020

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Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

The Journal of neuroscience, 2009-10, Vol.29 (41), p.12957-12969

2009

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Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry

Journal of visualized experiments, 2015-12 (106), p.e53205-e53205

2015

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Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats

PloS one, 2012-05, Vol.7 (5), p.e38170

2012

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FRET and Flow Cytometry Assays to Measure Proteopathic Seeding Activity in Biological Samples

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1523, p.349

2017

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Evaluation of the benefits of exercise on cognition in major depressive disorder

General hospital psychiatry, 2017-11, Vol.49, p.19-25

2017

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Early Engineering Approaches to Improve Peptide Developability and Manufacturability

The AAPS journal, 2015-01, Vol.17 (1), p.111-120

2015

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Positive and negative valence systems in major depression have distinct clinical features, response to antidepressants, and relationships with immunomarkers

Depression and anxiety, 2020-08, Vol.37 (8), p.771-783

2020

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A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

Clinical and translational science, 2023-08, Vol.16 (8), p.1431-1444

2023

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Interleukin-1β-dependent Signaling between Astrocytes and Neurons Depends Critically on Astrocytic Calcineurin/NFAT Activity

The Journal of biological chemistry, 2008-08, Vol.283 (32), p.21953-21964

2008

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Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function

Biochimica et biophysica acta, 2016-09, Vol.1862 (9), p.1521-1532

2016

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Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology

Journal of visualized experiments, 2011-03 (49)

2011

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Turn-On DNA Damage Sensors for the Direct Detection of 8-Oxoguanine and Photoproducts in Native DNA

Journal of the American Chemical Society, 2011-08, Vol.133 (32), p.12518-12527

2011

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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

Proteopathic tau seeding predicts tauopathy in vivo

Peripheral biomarkers of major depression and antidepressant treatment response: Current knowledge and future outlooks

A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in Escherichia coli

Targeting astrocytes ameliorates neurologic changes in a mouse model of Alzheimer's disease

Parkinson’s disease and multiple system atrophy have distinct α-synuclein seed characteristics

Calcineurin and glial signaling: neuroinflammation and beyond

Widespread tau seeding activity at early Braak stages

A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes

Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury

Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Aβ-Bearing Mice

Dysfunctional adaptive immune response in adolescents and young adults with suicide behavior

Cognitive Decline in Alzheimer's Disease Is Associated with Selective Changes in Calcineurin/NFAT Signaling

Sensitive Detection of Proteopathic Seeding Activity with FRET Flow Cytometry

Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats

FRET and Flow Cytometry Assays to Measure Proteopathic Seeding Activity in Biological Samples

Evaluation of the benefits of exercise on cognition in major depressive disorder

Early Engineering Approaches to Improve Peptide Developability and Manufacturability

Positive and negative valence systems in major depression have distinct clinical features, response to antidepressants, and relationships with immunomarkers

A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

Interleukin-1β-dependent Signaling between Astrocytes and Neurons Depends Critically on Astrocytic Calcineurin/NFAT Activity

Calcineurin proteolysis in astrocytes: Implications for impaired synaptic function

Preparation of acute hippocampal slices from rats and transgenic mice for the study of synaptic alterations during aging and amyloid pathology

Turn-On DNA Damage Sensors for the Direct Detection of 8-Oxoguanine and Photoproducts in Native DNA

Can artificial intelligence accelerate the diagnosis of inherited retinal diseases? Protocol for a data-only retrospective cohort study (Eye2Gene)

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