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Discovery of MRSA active antibiotics using primary sequence from the human microbiome

Nature chemical biology, 2016-12, Vol.12 (12), p.1004-1006

2016

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Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

Bioorganic & medicinal chemistry letters, 2013-05, Vol.23 (10), p.3039-3043

2013

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Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF

PLoS biology, 2019-02, Vol.17 (2), p.e3000123-e3000123

2019

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Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Journal of the American Chemical Society, 2017-02, Vol.139 (4), p.1404-1407

2017

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Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction

Journal of biomolecular screening, 2012-04, Vol.17 (4), p.435-447

2012

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Enzyme-mediated hydrolytic activation of prodrugs

Acta pharmaceutica Sinica. B, 2011-10, Vol.1 (3), p.143-159

2011

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intrinsic conformational propensities of the 20 naturally occurring amino acids and reflection of these propensities in proteins

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (34), p.12259-12264

2008

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Pruned Machine Learning Models to Predict Aqueous Solubility

ACS omega, 2020-07, Vol.5 (27), p.16562-16567

2020

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AutoDesigner - Core Design, a De Novo Design Algorithm for Chemical Scaffolds: Application to the Design and Synthesis of Novel Selective Wee1 Inhibitors

Journal of chemical information and modeling, 2024-10, Vol.64 (19), p.7513-7524

2024

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Kinetic Analyses of Keap1-Nrf2 Interaction and Determination of the Minimal Nrf2 Peptide Sequence Required for Keap1 Binding Using Surface Plasmon Resonance

Chemical biology & drug design, 2011-12, Vol.78 (6), p.1014-1021

2011

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Human Microbiome Inspired Antibiotics with Improved β‑Lactam Synergy against MDR Staphylococcus aureus

ACS infectious diseases, 2018-01, Vol.4 (1), p.33-38

2018

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The discovery of small-molecule inhibitors of Keap1-Nrf2 interaction with homogeneous fluorescence-based high throughput screening assays

Inoyama, Daigo

2014

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ENZYMES AND TARGETED ACTIVATION OF PRODRUGS

Enzyme Technologies, 2013, p.163-235

2013

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Discovery of MRSA active antibiotics using primary sequence from the human microbiome

Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction

Structural basis of DSF recognition by its receptor RpfR and its regulatory interaction with the DSF synthase RpfF

Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction

Enzyme-mediated hydrolytic activation of prodrugs

intrinsic conformational propensities of the 20 naturally occurring amino acids and reflection of these propensities in proteins

Pruned Machine Learning Models to Predict Aqueous Solubility

AutoDesigner - Core Design, a De Novo Design Algorithm for Chemical Scaffolds: Application to the Design and Synthesis of Novel Selective Wee1 Inhibitors

Kinetic Analyses of Keap1-Nrf2 Interaction and Determination of the Minimal Nrf2 Peptide Sequence Required for Keap1 Binding Using Surface Plasmon Resonance

Human Microbiome Inspired Antibiotics with Improved β‑Lactam Synergy against MDR Staphylococcus aureus

The discovery of small-molecule inhibitors of Keap1-Nrf2 interaction with homogeneous fluorescence-based high throughput screening assays

ENZYMES AND TARGETED ACTIVATION OF PRODRUGS

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