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Evaluation of 6-OxP-CD, an Oxime-based cyclodextrin as a viable medical countermeasure against nerve agent poisoning: Experimental and molecular dynamic simulation studies on its inclusion complexes with cyclosarin, soman and VX

PloS one, 2023-03, Vol.18 (3), p.e0283181-e0283181

2023

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Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data

The journal of physical chemistry. B, 2017-05, Vol.121 (20), p.5228-5237

2017

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Countermeasures for Preventing and Treating Opioid Overdose

Clinical pharmacology and therapeutics, 2021-03, Vol.109 (3), p.578-590

2021

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Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

Science translational medicine, 2015-07, Vol.7 (298), p.298ra117

2015

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Comparative Pharmacokinetics of High and Low Doses of the Herbicide Propanil in Mice

Chemical research in toxicology, 2018-10, Vol.31 (10), p.1080-1085

2018

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Use of Accelerator Mass Spectrometry in Human Health and Molecular Toxicology

Chemical research in toxicology, 2016-12, Vol.29 (12), p.1976-1986

2016

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Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel

Chemical research in toxicology, 2018-12, Vol.31 (12), p.1293-1304

2018

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Toward Predicting Acute Myeloid Leukemia Patient Response to 7 + 3 Induction Chemotherapy via Diagnostic Microdosing

Chemical research in toxicology, 2018-10, Vol.31 (10), p.1042-1051

2018

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Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2‑Amino-1-methyl-6-phenylimidazo[4,5‑b]pyridine and Albumin in Humans

Chemical research in toxicology, 2017-02, Vol.30 (2), p.705-714

2017

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Tracking Tumor Colonization in Xenograft Mouse Models Using Accelerator Mass Spectrometry

Scientific reports, 2018-10, Vol.8 (1), p.15013-10, Article 15013

2018

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P165 - Improved on-line accelerator mass spectrometry techniques for the analysis of environmental chemicals at ultra-low exposure levels

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S73-S73

2020

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Mutagenic potency of food-derived heterocyclic amines

Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2007-03, Vol.616 (1), p.90-94

2007

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Disposition of the Dietary Mutagen 2‑Amino-3,8-dimethylimidazo[4,5‑f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans

Chemical research in toxicology, 2016-03, Vol.29 (3), p.352-358

2016

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Diagnostic Microdosing Approach to Study Gemcitabine Resistance

Chemical research in toxicology, 2016-11, Vol.29 (11), p.1843-1848

2016

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Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

PloS one, 2016-01, Vol.11 (1), p.e0146256

2016

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The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10541-10547

2006

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N-Glucuronidation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) and N-hydroxy-PhIP by specific human UDP-glucuronosyltransferases

Carcinogenesis (New York), 2001-07, Vol.22 (7), p.1087-1093

2001

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Human UDP-Glucuronosyltransferase 1A1 Is the Primary Enzyme Responsible for the N-Glucuronidation of N-Hydroxy-PhIP in Vitro

Chemical research in toxicology, 2004-08, Vol.17 (8), p.1137-1144

2004

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Radiocarbon Tracers in Toxicology and Medicine: Recent Advances in Technology and Science

Toxics (Basel), 2019-05, Vol.7 (2), p.27

2019

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A microdosing approach for characterizing formation and repair of carboplatin–DNA monoadducts and chemoresistance

International journal of cancer, 2011-09, Vol.129 (6), p.1425-1434

2011

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DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

Methods in molecular biology (Clifton, N.J.), 2014, Vol.1105, p.147

2014

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A Comprehensive Investigation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach

Chemical research in toxicology, 2007-03, Vol.20 (3), p.531-542

2007

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Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Carcinogenesis (New York), 2007-03, Vol.28 (3), p.732-737

2007

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What Do Diet-Induced Changes in Phase I and II Enzymes Tell Us about Prevention from Exposure to Heterocyclic Amines?

The Journal of nutrition, 2006-10, Vol.136 (10), p.2683S-2684S

2006

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Human exposure to heterocyclic amine food mutagens/carcinogens: Relevance to breast cancer

Environmental and molecular mutagenesis, 2002, Vol.39 (2-3), p.112-118

2002

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Evaluation of 6-OxP-CD, an Oxime-based cyclodextrin as a viable medical countermeasure against nerve agent poisoning: Experimental and molecular dynamic simulation studies on its inclusion complexes with cyclosarin, soman and VX

Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data

Countermeasures for Preventing and Treating Opioid Overdose

Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

Comparative Pharmacokinetics of High and Low Doses of the Herbicide Propanil in Mice

Use of Accelerator Mass Spectrometry in Human Health and Molecular Toxicology

Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel

Toward Predicting Acute Myeloid Leukemia Patient Response to 7 + 3 Induction Chemotherapy via Diagnostic Microdosing

Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2‑Amino-1-methyl-6-phenylimidazo[4,5‑b]pyridine and Albumin in Humans

Tracking Tumor Colonization in Xenograft Mouse Models Using Accelerator Mass Spectrometry

P165 - Improved on-line accelerator mass spectrometry techniques for the analysis of environmental chemicals at ultra-low exposure levels

Mutagenic potency of food-derived heterocyclic amines

Disposition of the Dietary Mutagen 2‑Amino-3,8-dimethylimidazo[4,5‑f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans

Diagnostic Microdosing Approach to Study Gemcitabine Resistance

Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

N-Glucuronidation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) and N-hydroxy-PhIP by specific human UDP-glucuronosyltransferases

Human UDP-Glucuronosyltransferase 1A1 Is the Primary Enzyme Responsible for the N-Glucuronidation of N-Hydroxy-PhIP in Vitro

Radiocarbon Tracers in Toxicology and Medicine: Recent Advances in Technology and Science

A microdosing approach for characterizing formation and repair of carboplatin–DNA monoadducts and chemoresistance

DNA isolation and sample preparation for quantification of adduct levels by accelerator mass spectrometry

A Comprehensive Investigation of 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) Metabolism in the Mouse Using a Multivariate Data Analysis Approach

Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

What Do Diet-Induced Changes in Phase I and II Enzymes Tell Us about Prevention from Exposure to Heterocyclic Amines?

Human exposure to heterocyclic amine food mutagens/carcinogens: Relevance to breast cancer

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