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The mechanistic basis of prostacyclin and its stable analogues in pulmonary arterial hypertension: Role of membrane versus nuclear receptors

Prostaglandins & other lipid mediators, 2015-07, Vol.120, p.56-71

2015

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Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: Treprostinil is a potent DP1 and EP2 agonist

Biochemical pharmacology, 2012-07, Vol.84 (1), p.68-75

2012

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Thomas (Tom) B. Bolton – a major force in smooth muscle research

The Journal of physiology, 2024-08, Vol.602 (15), p.3601-3604

2024

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International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions

Pharmacological reviews, 2020-10, Vol.72 (4), p.910-968

2020

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International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E 2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions

Pharmacological reviews, 2020-10, Vol.72 (4), p.910-968

2020

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Vasopressin: Mechanisms of action on the vasculature in health and in septic shock

Critical care medicine, 2007-01, Vol.35 (1), p.33-40

2007

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Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2010-11, Vol.182 (9), p.1161-1170

2010

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Relative Recovery of Non-Alcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Rats

Nutrients, 2023-12, Vol.16 (1), p.115

2023

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Exploring the enzymatic degradation of poly(glycerol adipate)

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.377-386

2019

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Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension

British journal of pharmacology, 2020-01, Vol.177 (1), p.161-174

2020

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Prostacyclin mimetics inhibit DRP1-mediated pro-proliferative mitochondrial fragmentation in pulmonary arterial hypertension

Vascular pharmacology, 2023-08, Vol.151, p.107194-107194, Article 107194

2023

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Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension

Biochemical pharmacology, 2019-08, Vol.166, p.242-252

2019

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The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels

Frontiers in pharmacology, 2021-06, Vol.12, p.705421-705421

2021

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Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature

Clinical epigenetics, 2022-08, Vol.14 (1), p.1-98, Article 98

2022

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Adverse Events of Prostacyclin Mimetics in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis

Journal of clinical medicine, 2019-04, Vol.8 (4), p.481

2019

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Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients

Prostaglandins & other lipid mediators, 2020-02, Vol.146, p.106388-106388, Article 106388

2020

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Role of KATP channels in sepsis

Cardiovascular research, 2006-11, Vol.72 (2), p.220-230

2006

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Selexipag in the management of pulmonary arterial hypertension: an update

Drug, healthcare and patient safety, 2019-08, Vol.11, p.55-64

2019

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The role of microvesicles as biomarkers in the screening of colorectal neoplasm

Cancer medicine (Malden, MA), 2022-08, Vol.11 (15), p.2957-2968

2022

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Differential Effects of Stable Prostacyclin Analogs on Smooth Muscle Proliferation and Cyclic AMP Generation in Human Pulmonary Artery

American journal of respiratory cell and molecular biology, 2002-02, Vol.26 (2), p.194-201

2002

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Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology

Circulation. Genomic and precision medicine, 2018-02, Vol.11 (2), p.e001813-e001813

2018

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The large-conductance Ca2+-activated K+ channel is essential for innate immunity

Nature (London), 2004-02, Vol.427 (6977), p.853-858

2004

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Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis

Critical care medicine, 2007-10, Vol.35 (10), p.2337-2343

2007

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A Mechanism for ATP-Sensitive Potassium Channel Diversity: Functional Coassembly of Two Pore-Forming Subunits

Proceedings of the National Academy of Sciences - PNAS, 2001-01, Vol.98 (2), p.729-734

2001

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Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heart

Pulmonary circulation, 2017-04, Vol.7 (2), p.339-347

2017

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The mechanistic basis of prostacyclin and its stable analogues in pulmonary arterial hypertension: Role of membrane versus nuclear receptors

Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and iloprost, at human prostanoid receptors: Treprostinil is a potent DP1 and EP2 agonist

Thomas (Tom) B. Bolton – a major force in smooth muscle research

International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1–4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions

International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E 2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions

Vasopressin: Mechanisms of action on the vasculature in health and in septic shock

Smooth Muscle Proliferation and Role of the Prostacyclin (IP) Receptor in Idiopathic Pulmonary Arterial Hypertension

Relative Recovery of Non-Alcoholic Fatty Liver Disease (NAFLD) in Diet-Induced Obese Rats

Exploring the enzymatic degradation of poly(glycerol adipate)

Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension

Prostacyclin mimetics inhibit DRP1-mediated pro-proliferative mitochondrial fragmentation in pulmonary arterial hypertension

Pharmacology of the single isomer, esuberaprost (beraprost-314d) on pulmonary vascular tone, IP receptors and human smooth muscle proliferation in pulmonary hypertension

The Prostacyclin Analogue, Treprostinil, Used in the Treatment of Pulmonary Arterial Hypertension, is a Potent Antagonist of TREK-1 and TREK-2 Potassium Channels

Therapeutic potential of inhibiting histone 3 lysine 27 demethylases: a review of the literature

Adverse Events of Prostacyclin Mimetics in Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis

Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients

Role of KATP channels in sepsis

Selexipag in the management of pulmonary arterial hypertension: an update

The role of microvesicles as biomarkers in the screening of colorectal neoplasm

Differential Effects of Stable Prostacyclin Analogs on Smooth Muscle Proliferation and Cyclic AMP Generation in Human Pulmonary Artery

Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology

The large-conductance Ca2+-activated K+ channel is essential for innate immunity

Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis

A Mechanism for ATP-Sensitive Potassium Channel Diversity: Functional Coassembly of Two Pore-Forming Subunits

Prostacyclins have no direct inotropic effect on isolated atrial strips from the normal and pressure-overloaded human right heart

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