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An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors

Scientific reports, 2020-08, Vol.10 (1), p.13866-13866, Article 13866

2020

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Ritanserin blocks CaV1.2 channels in rat artery smooth muscles: electrophysiological, functional, and computational studies

Acta pharmacologica Sinica, 2020-09, Vol.41 (9), p.1158-1166

2020

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HGA Triggers SAA Aggregation and Accelerates Fibril Formation in the C20/A4 Alkaptonuria Cell Model

Cells (Basel, Switzerland), 2024-09, Vol.13 (17), p.1501

2024

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Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits CaV1.2 and Stimulates KCa1.1 Channels

Marine drugs, 2022-08, Vol.20 (8), p.515

2022

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Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste

Applied sciences, 2024-08, Vol.14 (15), p.6552

2024

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2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: Synthesis, In Silico Analysis and In Vitro Pharmacological Evaluation

MolBank, 2021-09, Vol.2021 (3), p.M1258

2021

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From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel

PeerJ (San Francisco, CA), 2018-05, Vol.6, p.e4680-e4680, Article e4680

2018

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Cav1.2 channel current block by the PKA inhibitor H-89 in rat tail artery myocytes via a PKA-independent mechanism: Electrophysiological, functional, and molecular docking studies

Biochemical pharmacology, 2017-09, Vol.140, p.53-63

2017

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Identification of Inhibitors Binding Site of Ebola L Polymerase Based on its Homology Model

Journal of Virology & Antiviral Research, 2016, Vol.5 (4)

Trezza, Alfonso

2016

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ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

European journal of human genetics : EJHG, 2020-11, Vol.28 (11), p.1602-1614

2020

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A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of CaV1.2 and KCa1.1 channels

Biochemical pharmacology, 2021-03, Vol.185, p.114429-114429, Article 114429

2021

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Ca v 1.2 channel current block by the PKA inhibitor H-89 in rat tail artery myocytes via a PKA-independent mechanism: Electrophysiological, functional, and molecular docking studies

Biochemical pharmacology, 2017-09, Vol.140, p.53-63

2017

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Phytochemical Composition, Anti-Inflammatory Property, and Anti-Atopic Effect of IChaetomorpha linum/I Extract

Marine drugs, 2024-05, Vol.22 (5)

2024

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Structural Bioinformatic Survey of Protein-Small Molecule Interfaces Delineates the Role of Glycine in Surface Pocket Formation

IEEE/ACM transactions on computational biology and bioinformatics, 2022-05, Vol.19 (3), p.1881-1886

2022

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The surge of flavonoids as novel, fine regulators of cardiovascular Cav channels

European journal of pharmacology, 2017-02, Vol.796, p.158-174

2017

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Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators

Bioorganic chemistry, 2020-12, Vol.105, p.104404-104404, Article 104404

2020

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Dynamin-independent Ca V 1.2 and K Ca 1.1 channels regulation and vascular tone modulation by the mitochondrial fission inhibitors dynasore and dyngo-4a

European journal of pharmacology, 2023-07, Vol.951, p.175786

2023

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Targeting neuronal calcium channels and GSK3β for Alzheimer’s disease with naturally-inspired Diels-Alder adducts

Bioorganic chemistry, 2022-12, Vol.129, p.106152-106152, Article 106152

2022

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Artificial intelligence-driven identification of morin analogues acting as Ca V 1.2 channel blockers: Synthesis and biological evaluation

Bioorganic chemistry, 2023-02, Vol.131, p.106326

2023

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Vasorelaxing Activity of R-(-)-3'-Hydroxy-2,4,5-trimethoxydalbergiquinol from Dalbergia tonkinensis: Involvement of Smooth Muscle CaV1.2 Channels

Planta medica, 2020-03, Vol.86 (4), p.284-293

2020

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Exploring the Antioxidant and Anti-Inflammatory Potential of Saffron (Crocus sativus) Tepals Extract within the Circular Bioeconomy

Antioxidants, 2024-09, Vol.13 (9), p.1082

2024

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A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of Ca V 1.2 and K Ca 1.1 channels

Biochemical pharmacology, 2021-03, Vol.185, p.114429

2021

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Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular K Ca 1.1 channel stimulators

Bioorganic chemistry, 2020-12, Vol.105, p.104404

2020

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Ritanserin blocks Ca V 1.2 channels in rat artery smooth muscles: electrophysiological, functional, and computational studies

Acta pharmacologica Sinica, 2020-09, Vol.41 (9), p.1158

2020

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The Selective Rat Toxicant Norbormide Blocks K ATP Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells

Frontiers in pharmacology, 2019, Vol.10, p.598

2019

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An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors

Ritanserin blocks CaV1.2 channels in rat artery smooth muscles: electrophysiological, functional, and computational studies

HGA Triggers SAA Aggregation and Accelerates Fibril Formation in the C20/A4 Alkaptonuria Cell Model

Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits CaV1.2 and Stimulates KCa1.1 Channels

Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste

2-Hydroxy-5-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: Synthesis, In Silico Analysis and In Vitro Pharmacological Evaluation

From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel

Cav1.2 channel current block by the PKA inhibitor H-89 in rat tail artery myocytes via a PKA-independent mechanism: Electrophysiological, functional, and molecular docking studies

Identification of Inhibitors Binding Site of Ebola L Polymerase Based on its Homology Model

ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of CaV1.2 and KCa1.1 channels

Ca v 1.2 channel current block by the PKA inhibitor H-89 in rat tail artery myocytes via a PKA-independent mechanism: Electrophysiological, functional, and molecular docking studies

Phytochemical Composition, Anti-Inflammatory Property, and Anti-Atopic Effect of IChaetomorpha linum/I Extract

Structural Bioinformatic Survey of Protein-Small Molecule Interfaces Delineates the Role of Glycine in Surface Pocket Formation

The surge of flavonoids as novel, fine regulators of cardiovascular Cav channels

Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular KCa1.1 channel stimulators

Dynamin-independent Ca V 1.2 and K Ca 1.1 channels regulation and vascular tone modulation by the mitochondrial fission inhibitors dynasore and dyngo-4a

Targeting neuronal calcium channels and GSK3β for Alzheimer’s disease with naturally-inspired Diels-Alder adducts

Artificial intelligence-driven identification of morin analogues acting as Ca V 1.2 channel blockers: Synthesis and biological evaluation

Vasorelaxing Activity of R-(-)-3'-Hydroxy-2,4,5-trimethoxydalbergiquinol from Dalbergia tonkinensis: Involvement of Smooth Muscle CaV1.2 Channels

Exploring the Antioxidant and Anti-Inflammatory Potential of Saffron (Crocus sativus) Tepals Extract within the Circular Bioeconomy

A multitarget semi-synthetic derivative of the flavonoid morin with improved in vitro vasorelaxant activity: Role of Ca V 1.2 and K Ca 1.1 channels

Design, synthesis and pharmacological evaluation of ester-based quercetin derivatives as selective vascular K Ca 1.1 channel stimulators

Ritanserin blocks Ca V 1.2 channels in rat artery smooth muscles: electrophysiological, functional, and computational studies

The Selective Rat Toxicant Norbormide Blocks K ATP Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells

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