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0.45% saline and 5% dextrose in water, but not 0.9% saline or 5% dextrose in 0.9% saline, worsen brain edema two hours after closed head trauma in rats two hours after closed head trauma in rats

Anesthesia and analgesia, 1998, Vol.86 (6), p.1225-1229

1998

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1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist

Journal of medicinal chemistry, 1995-11, Vol.38 (23), p.4634-4636

1995

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1-2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (10), p.3125-3128

2010

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1,2,3-Triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: a new class of A2A adenosine receptor antagonists

Farmaco (Società chimica italiana : 1989), 1996-04, Vol.51 (4), p.297

1996

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1,2,4-Triazolo[3,4- a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (19), p.2619-2622

2001

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1,2,5,6-tetrahydropyridine oxime ethers incorporating electron withdrawing groups are potent and selective muscarinic agonists

Bioorganic & medicinal chemistry letters, 1994-02, Vol.4 (4), p.557-562

1994

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1-[2-[(5-Cyanopyridin-2-yl)amino]-ethylamino]acetyl-2-(S)-pyrrolidine-carbonitri le: A potent, selective, and orally bioavailable Dipeptidyl peptidase IV inhibitor with antihyperglycemic properties

Journal of medicinal chemistry, 2002, Vol.45 (12), p.2362-2365

2002

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1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: A Potent Serotonin 5-HT2A/2C Agonist

Journal of medicinal chemistry, 1994-12, Vol.37 (25), p.4346-4351

1994

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1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.379-392

1998

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1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents

Journal of medicinal chemistry, 1995-10, Vol.38 (22), p.4570-4578

1995

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1,2-dibromoethane and chloroform in the rainbow trout (Salmo Gairdneri): studies on the distribution of nonvolatile and irreversibly bound metabolites

Journal of toxicology and environmental health, 1989-01, Vol.26 (2), p.209-221

1989

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1,2-Dibromoethane initiation of hepatic nodules in Sprague-Dawley rats selected with Solt-Farber system

Archives of toxicology, 1985-12, Vol.58 (2), p.118-119

1985

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1, 2-Dithiol-3-thione analogs: effects on NAD(P)H: quinone reductase and glutathione levels in murine hepatoma cells

Carcinogenesis (New York), 1986-06, Vol.7 (6), p.977-980

1986

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1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (16), p.1867-1870

2000

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1,25-Dihydroxyvitamin D and vitamin D-binding protein are both decreased in streptozotocin-diabetic rats

Endocrinology (Philadelphia), 1985-06, Vol.116 (6), p.2483-2488

1985

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1,25-Dihydroxyvitamin D as a Cardiovascular Hormone Effects on Calcium Current and Cytosolic Free Calcium in Vascular Smooth Muscle Cells

American journal of hypertension, 1993-12, Vol.6 (12), p.983-988

1993

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1,25-Dihydroxyvitamin D3 induces splenocyte apoptosis and enhances BALB/c mice sensitivity to toxoplasmosis

The Journal of steroid biochemistry and molecular biology, 2005-07, Vol.96 (2), p.179-185

2005

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1,25-dihydroxyvitamin D3 inhibits transcription of type I collagen genes in the rat osteosarcoma cell line ROS 17/2.8

Endocrinology (Philadelphia), 1989-07, Vol.125 (1), p.327-333

1989

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1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one : A selective high-affinity antagonist for the human dopamine D4receptor with excellent selectivity over ion channels

Journal of medicinal chemistry, 1999, Vol.42 (14), p.2706-2715

1999

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1,3-dialkyltriazenes : reactie intermediates and DNA alkylation

Chemical research in toxicology, 1991, Vol.4 (3), p.334-340

1991

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1,3-dioxane-4,6-dione-5-carboxamide-based inhibitors of human group IIa phospholipase A2 : X-ray structure of the complex and interfacial selection of inhibitors from a structural library

Bioorganic & medicinal chemistry letters, 1999-04, Vol.9 (8), p.1097-1102

1999

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1,4-Benzodiazepin-2-one derived neurokinin-1 receptor antagonists

Bioorganic & medicinal chemistry letters, 1997-08, Vol.7 (15), p.2037-2042

1997

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1,4-Bis-(2,3-epoxypropylamino)-9,10-anthracenedione and related compounds as potent antifungal and antimicrobial agents

Bioorganic & medicinal chemistry letters, 1997-12, Vol.7 (24), p.3153-3158

1997

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1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-ylmethanamine: A Wingless β-Catenin Agonist That Increases Bone Formation Rate

Journal of medicinal chemistry, 2009, Vol.52 (22), p.6962-6965

2009

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1,4-substituted indoles: a potent and selective class of angiotensin II receptor antagonists

Bioorganic & medicinal chemistry letters, 1994-01, Vol.4 (1), p.145-150

1994

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0.45% saline and 5% dextrose in water, but not 0.9% saline or 5% dextrose in 0.9% saline, worsen brain edema two hours after closed head trauma in rats two hours after closed head trauma in rats

1-{1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4-yl}-4H-3,1-benzoxazin-2(1H)-one (L-371,257) : a new, orally bioavailable, non-peptide oxytocin antagonist

1-2-(2,2,2-Trifluoroethoxy)ethyl-1H-pyrazolo[4,3-d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors

1,2,3-Triazolo[5,4-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: a new class of A2A adenosine receptor antagonists

1,2,4-Triazolo[3,4- a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists

1,2,5,6-tetrahydropyridine oxime ethers incorporating electron withdrawing groups are potent and selective muscarinic agonists

1-[2-[(5-Cyanopyridin-2-yl)amino]-ethylamino]acetyl-2-(S)-pyrrolidine-carbonitri le: A potent, selective, and orally bioavailable Dipeptidyl peptidase IV inhibitor with antihyperglycemic properties

1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: A Potent Serotonin 5-HT2A/2C Agonist

1,2,5-Thiadiazole Analogues of Aceclidine as Potent m1 Muscarinic Agonists

1,2-Diarylcyclopentenes as Selective Cyclooxygenase-2 Inhibitors and Orally Active Anti-inflammatory Agents

1,2-dibromoethane and chloroform in the rainbow trout (Salmo Gairdneri): studies on the distribution of nonvolatile and irreversibly bound metabolites

1,2-Dibromoethane initiation of hepatic nodules in Sprague-Dawley rats selected with Solt-Farber system

1, 2-Dithiol-3-thione analogs: effects on NAD(P)H: quinone reductase and glutathione levels in murine hepatoma cells

1-[2-[(Heteroarylmethoxy)aryl]carbamoyl]indolines are selective and orally active 5-HT2C receptor inverse agonists

1,25-Dihydroxyvitamin D and vitamin D-binding protein are both decreased in streptozotocin-diabetic rats

1,25-Dihydroxyvitamin D as a Cardiovascular Hormone Effects on Calcium Current and Cytosolic Free Calcium in Vascular Smooth Muscle Cells

1,25-Dihydroxyvitamin D3 induces splenocyte apoptosis and enhances BALB/c mice sensitivity to toxoplasmosis

1,25-dihydroxyvitamin D3 inhibits transcription of type I collagen genes in the rat osteosarcoma cell line ROS 17/2.8

1-(3-Cyanobenzylpiperidin-4-yl)-5-methyl-4-phenyl-1,3-dihydroimidazol-2-one : A selective high-affinity antagonist for the human dopamine D4receptor with excellent selectivity over ion channels

1,3-dialkyltriazenes : reactie intermediates and DNA alkylation

1,3-dioxane-4,6-dione-5-carboxamide-based inhibitors of human group IIa phospholipase A2 : X-ray structure of the complex and interfacial selection of inhibitors from a structural library

1,4-Benzodiazepin-2-one derived neurokinin-1 receptor antagonists

1,4-Bis-(2,3-epoxypropylamino)-9,10-anthracenedione and related compounds as potent antifungal and antimicrobial agents

1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-ylmethanamine: A Wingless β-Catenin Agonist That Increases Bone Formation Rate

1,4-substituted indoles: a potent and selective class of angiotensin II receptor antagonists

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