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Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

Digestive diseases and sciences, 2015-11, Vol.60 (11), p.3318-3328

2015

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Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

The Journal of pharmacology and experimental therapeutics, 2013-12, Vol.347 (3), p.727

2013

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Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.388

2005

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Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

The Journal of pharmacology and experimental therapeutics, 2015-05, Vol.353 (2), p.415

2015

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Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol

BMC cancer, 2022-04, Vol.22 (1), p.416-416, Article 416

2022

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Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation

Antimicrobial agents and chemotherapy, 2015-07, Vol.59 (7), p.3935-3943

2015

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Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Molecular pharmacology, 2013-08, Vol.84 (2), p.182-189

2013

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Androgen Deprivation therapy for Oligo-recurrent Prostate cancer in addition to radioTherapy (ADOPT): study protocol for a randomised phase III trial

BMC cancer, 2022-05, Vol.22 (1), p.482-482, Article 482

2022

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Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

Clinical pharmacology and therapeutics, 2014-11, Vol.96 (5), p.589-598

2014

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A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function

PloS one, 2018-05, Vol.13 (5), p.e0197213

2018

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Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation

Drug metabolism and disposition, 2014-11, Vol.42 (11), p.1964

2014

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Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes

Toxicology and applied pharmacology, 2012-05, Vol.261 (1), p.1-9

2012

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Association of CYP2D6 and CYP2C19 metabolizer status with switching and discontinuing antidepressant drugs: an exploratory study

BMC psychiatry, 2024-05, Vol.24 (1), p.394-394, Article 394

2024

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Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.899-906

2019

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Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.283-294

2019

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Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes

Drug metabolism and disposition, 2008-01, Vol.36 (1), p.198

2008

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Cefazolin pharmacokinetics in premature infants

Journal of perinatology, 2019-09, Vol.39 (9), p.1213-1218

2019

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Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion

Drug metabolism and disposition, 2014-07, Vol.42 (7), p.1219

2014

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Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats

Drug metabolism and disposition, 2006-04, Vol.34 (4), p.556

2006

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Influence of Seeding Density and Extracellular Matrix on Bile Acid Transport and Mrp4 Expression in Sandwich-Cultured Mouse Hepatocytes

Molecular pharmaceutics, 2010-04, Vol.7 (2), p.491-500

2010

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug metabolism and disposition, 2013-06, Vol.41 (6), p.1179

2013

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In Vitro–In Vivo Correlation of Hepatobiliary Drug Clearance in Humans

Clinical pharmacology and therapeutics, 2007-03, Vol.81 (3), p.406-413

2007

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Development of a Population Pharmacokinetic Model To Describe Azithromycin Whole-Blood and Plasma Concentrations over Time in Healthy Subjects

Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3194-3201

2013

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Hepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver

The Journal of pharmacology and experimental therapeutics, 2013-12, Vol.347 (3), p.737

2013

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Pharmacokinetics and Safety of Fluconazole in Young Infants Supported With Extracorporeal Membrane Oxygenation

The Pediatric infectious disease journal, 2012-10, Vol.31 (10), p.1042-1047

2012

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Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol

Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation

Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Androgen Deprivation therapy for Oligo-recurrent Prostate cancer in addition to radioTherapy (ADOPT): study protocol for a randomised phase III trial

Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function

Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation

Endogenous bile acid disposition in rat and human sandwich-cultured hepatocytes

Association of CYP2D6 and CYP2C19 metabolizer status with switching and discontinuing antidepressant drugs: an exploratory study

Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease

Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species

Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes

Cefazolin pharmacokinetics in premature infants

Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion

Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats

Influence of Seeding Density and Extracellular Matrix on Bile Acid Transport and Mrp4 Expression in Sandwich-Cultured Mouse Hepatocytes

Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

In Vitro–In Vivo Correlation of Hepatobiliary Drug Clearance in Humans

Development of a Population Pharmacokinetic Model To Describe Azithromycin Whole-Blood and Plasma Concentrations over Time in Healthy Subjects

Hepatic basolateral efflux contributes significantly to rosuvastatin disposition II: characterization of hepatic elimination by basolateral, biliary, and metabolic clearance pathways in rat isolated perfused liver

Pharmacokinetics and Safety of Fluconazole in Young Infants Supported With Extracorporeal Membrane Oxygenation

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