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Improving automatic delineation for head and neck organs at risk by Deep Learning Contouring

Radiotherapy and oncology, 2020-01, Vol.142, p.115-123

2020

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CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines

Radiotherapy and oncology, 2015-10, Vol.117 (1), p.83-90

2015

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Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

Clinical pharmacology and therapeutics, 2015-09, Vol.98 (3), p.266-287

2015

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Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-Cultured Hepatocytes, Mechanistic Modeling, and Simulation

The Journal of pharmacology and experimental therapeutics, 2016-08, Vol.358 (2), p.324

2016

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Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

The Journal of pharmacology and experimental therapeutics, 2013-12, Vol.347 (3), p.727

2013

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A Perspective on Efflux Transport Proteins in the Liver

Clinical pharmacology and therapeutics, 2012-11, Vol.92 (5), p.599-612

2012

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An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

Journal of pharmaceutical sciences, 2013-09, Vol.102 (9), p.3037-3057

2013

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In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.95-112

2013

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Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.665

2014

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Identifying patients who may benefit from adaptive radiotherapy: Does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help?

Radiotherapy and oncology, 2015-06, Vol.115 (3), p.285-294

2015

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Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids

Analytical chemistry (Washington), 2016-07, Vol.88 (14), p.7041-7048

2016

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.126-141

2013

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The complexities of hepatic drug transport: current knowledge and emerging concepts

Pharmaceutical research, 2004-05, Vol.21 (5), p.719-735

2004

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Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?

Toxicological sciences, 2016-01, Vol.149 (1), p.237-250

2016

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Influence of Drug Transport Proteins on the Pharmacokinetics and Drug Interactions of Hiv Protease Inhibitors

Journal of pharmaceutical sciences, 2011-09, Vol.100 (9), p.3636-3654

2011

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Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer’s Disease

Molecular pharmaceutics, 2018-09, Vol.15 (9), p.4073-4083

2018

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Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.55-64

2021

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In vitro to in vivo extrapolation for high throughput prioritization and decision making

Toxicology in vitro, 2018-03, Vol.47, p.213-227

2018

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Intestinal Permeability and Oral Absorption of Selected Drugs Are Reduced in a Mouse Model of Familial Alzheimer’s Disease

Molecular pharmaceutics, 2020-05, Vol.17 (5), p.1527-1537

2020

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Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

The Journal of pharmacology and experimental therapeutics, 2015-05, Vol.353 (2), p.415

2015

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Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Molecular pharmacology, 2013-08, Vol.84 (2), p.182-189

2013

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Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

Toxicological sciences, 2020-07, Vol.176 (1), p.34-45

2020

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Novel Mechanisms of Valproate Hepatotoxicity: Impaired Mrp2 Trafficking and Hepatocyte Depolarization

Toxicological sciences, 2019-10, Vol.171 (2), p.431-442

2019

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Role of hepatic efflux transporters in regulating systemic and hepatocyte exposure to xenobiotics

Annual review of pharmacology and toxicology, 2014-01, Vol.54 (1), p.509-535

2014

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Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.443-459

2016

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Improving automatic delineation for head and neck organs at risk by Deep Learning Contouring

CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines

Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-Cultured Hepatocytes, Mechanistic Modeling, and Simulation

Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

A Perspective on Efflux Transport Proteins in the Liver

An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4

Identifying patients who may benefit from adaptive radiotherapy: Does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help?

Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids

Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

The complexities of hepatic drug transport: current knowledge and emerging concepts

Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?

Influence of Drug Transport Proteins on the Pharmacokinetics and Drug Interactions of Hiv Protease Inhibitors

Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer’s Disease

Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications

In vitro to in vivo extrapolation for high throughput prioritization and decision making

Intestinal Permeability and Oral Absorption of Selected Drugs Are Reduced in a Mouse Model of Familial Alzheimer’s Disease

Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

Novel Mechanisms of Valproate Hepatotoxicity: Impaired Mrp2 Trafficking and Hepatocyte Depolarization

Role of hepatic efflux transporters in regulating systemic and hepatocyte exposure to xenobiotics

Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury

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