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Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

Digestive diseases and sciences, 2015-11, Vol.60 (11), p.3318-3328

2015

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Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

Clinical pharmacology and therapeutics, 2015-09, Vol.98 (3), p.266-287

2015

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A Perspective on Efflux Transport Proteins in the Liver

Clinical pharmacology and therapeutics, 2012-11, Vol.92 (5), p.599-612

2012

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In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.95-112

2013

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Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.665-674

2014

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.126-141

2013

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Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.55-64

2021

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Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.388-394

2005

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Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

Clinical pharmacology and therapeutics, 2014-11, Vol.96 (5), p.589-598

2014

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Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation

Drug metabolism and disposition, 2014-11, Vol.42 (11), p.1964-1970

2014

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Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.899-906

2019

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Mechanistic Modeling of the Hepatic Disposition of Estradiol-17 β -Glucuronide in Sandwich-Cultured Human Hepatocytes

Drug metabolism and disposition, 2020-02, Vol.48 (2), p.116-122

2020

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Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Clinical pharmacology and therapeutics, 2018-11, Vol.104 (5), p.916-932

2018

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Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species

Drug metabolism and disposition, 2019-03, Vol.47 (3), p.283-294

2019

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Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion

Drug metabolism and disposition, 2014-07, Vol.42 (7), p.1219-1226

2014

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Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes

Drug metabolism and disposition, 2008-01, Vol.36 (1), p.198-202

2008

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Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes

Drug metabolism and disposition, 2016-06, Vol.44 (6), p.867-870

2016

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Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions

Drug metabolism and disposition, 2019-10, Vol.47 (10), p.1222-1230

2019

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It Is Not Just the FEV1 That Matters, but the Personal Goals We Reach Along the Way: Qualitative, Multicenter, Prospective, Observational Study

Journal of medical Internet research, 2021-10, Vol.23 (10), p.e29218-e29218

2021

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Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats

Drug metabolism and disposition, 2006-04, Vol.34 (4), p.556-562

2006

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Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat

Drug metabolism and disposition, 2014-09, Vol.42 (9), p.1567-1574

2014

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug metabolism and disposition, 2013-06, Vol.41 (6), p.1179-1186

2013

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In Vitro–In Vivo Correlation of Hepatobiliary Drug Clearance in Humans

Clinical pharmacology and therapeutics, 2007-03, Vol.81 (3), p.406-413

2007

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Use of sandwich-cultured human hepatocytes to predict biliary clearance of angiotensin II receptor blockers and HMG-CoA reductase inhibitors

Drug metabolism and disposition, 2009-03, Vol.37 (3), p.447-452

2009

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Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation

The Pediatric infectious disease journal, 2012-10, Vol.31 (10), p.1042-1047

2012

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Altered Bile Acid Metabolome in Patients with Nonalcoholic Steatohepatitis

Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group

A Perspective on Efflux Transport Proteins in the Liver

In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development

Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4

Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Intestinal P‐gp and Putative Hepatic OATP1B Induction: International Transporter Consortium Perspective on Drug Development Implications

Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity

Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation

Altered Expression and Function of Hepatic Transporters in a Rodent Model of Polycystic Kidney Disease

Mechanistic Modeling of the Hepatic Disposition of Estradiol-17 β -Glucuronide in Sandwich-Cultured Human Hepatocytes

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

Continuum of Host-Gut Microbial Co-metabolism: Host CYP3A4/3A7 are Responsible for Tertiary Oxidations of Deoxycholate Species

Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion

Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes

Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes

Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions

It Is Not Just the FEV1 That Matters, but the Personal Goals We Reach Along the Way: Qualitative, Multicenter, Prospective, Observational Study

Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats

Role of multidrug resistance-associated protein 4 in the basolateral efflux of hepatically derived enalaprilat

Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

In Vitro–In Vivo Correlation of Hepatobiliary Drug Clearance in Humans

Use of sandwich-cultured human hepatocytes to predict biliary clearance of angiotensin II receptor blockers and HMG-CoA reductase inhibitors

Pharmacokinetics and safety of fluconazole in young infants supported with extracorporeal membrane oxygenation

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