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Producing circular field harmonics inside elliptic magnet apertures with superconducting canted-cosine-theta coils

Physical review. Accelerators and beams, 2024-02, Vol.27 (2), p.022402, Article 022402

Brouwer, L.

2024

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Developing evidence-based resources for evaluating postgraduate trainees in the biomedical sciences

PloS one, 2022-12, Vol.17 (12), p.e0278297

2022

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Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-Cultured Hepatocytes, Mechanistic Modeling, and Simulation

The Journal of pharmacology and experimental therapeutics, 2016-08, Vol.358 (2), p.324-333

2016

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Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

The Journal of pharmacology and experimental therapeutics, 2013-12, Vol.347 (3), p.727-736

2013

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Can they imagine the future? A qualitative study exploring the skills employers seek in pharmaceutical sciences doctoral graduates

PloS one, 2019-09, Vol.14 (9), p.e0222422

2019

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Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.665-674

2014

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A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity

Scientific reports, 2022-08, Vol.12 (1), p.14333-14, Article 14333

2022

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Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?

Toxicological sciences, 2016-01, Vol.149 (1), p.237-250

2016

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Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.388-394

2005

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Effect of mTOR inhibitors on sodium taurocholate cotransporting polypeptide (NTCP) function in vitro

Frontiers in pharmacology, 2023-03, Vol.14, p.1147495-1147495

2023

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Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

The Journal of pharmacology and experimental therapeutics, 2015-05, Vol.353 (2), p.415-423

2015

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Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol

BMC cancer, 2022-04, Vol.22 (1), p.416-416, Article 416

2022

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Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation

Antimicrobial agents and chemotherapy, 2015-07, Vol.59 (7), p.3935-3943

2015

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Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Molecular pharmacology, 2013-08, Vol.84 (2), p.182-189

2013

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A prospective cohort study on the absolute risks of venous thromboembolism and predictive value of screening asymptomatic relatives of patients with hereditary deficiencies of protein S, protein C or antithrombin

Journal of thrombosis and haemostasis, 2010-06, Vol.8 (6), p.1193-1200

2010

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Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

Toxicological sciences, 2020-07, Vol.176 (1), p.34-45

2020

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Androgen Deprivation therapy for Oligo-recurrent Prostate cancer in addition to radioTherapy (ADOPT): study protocol for a randomised phase III trial

BMC cancer, 2022-05, Vol.22 (1), p.482-482, Article 482

2022

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Novel Mechanisms of Valproate Hepatotoxicity: Impaired Mrp2 Trafficking and Hepatocyte Depolarization

Toxicological sciences, 2019-10, Vol.171 (2), p.431-442

2019

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A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function

PloS one, 2018-05, Vol.13 (5), p.e0197213

2018

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Applicability of somatic monitoring instructions in clinical practice guidelines on antipsychotic drug use

BMC psychiatry, 2021-04, Vol.21 (1), p.189-8, Article 189

2021

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Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation

Drug metabolism and disposition, 2014-11, Vol.42 (11), p.1964-1970

2014

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Predation risk is an ecological constraint for helper dispersal in a cooperatively breeding cichlid

Proceedings of the Royal Society. B, Biological sciences, 2004-11, Vol.271 (1555), p.2367-2374

2004

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Association of CYP2D6 and CYP2C19 metabolizer status with switching and discontinuing antidepressant drugs: an exploratory study

BMC psychiatry, 2024-05, Vol.24 (1), p.394-394, Article 394

2024

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Mechanistic Modeling of the Hepatic Disposition of Estradiol-17 β -Glucuronide in Sandwich-Cultured Human Hepatocytes

Drug metabolism and disposition, 2020-02, Vol.48 (2), p.116-122

2020

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E‑Cigarette Flavoring Chemicals Induce Cytotoxicity in HepG2 Cells

ACS omega, 2021-03, Vol.6 (10), p.6708-6713

2021

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Producing circular field harmonics inside elliptic magnet apertures with superconducting canted-cosine-theta coils

Developing evidence-based resources for evaluating postgraduate trainees in the biomedical sciences

Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-Cultured Hepatocytes, Mechanistic Modeling, and Simulation

Hepatic basolateral efflux contributes significantly to rosuvastatin disposition I: characterization of basolateral versus biliary clearance using a novel protocol in sandwich-cultured hepatocytes

Can they imagine the future? A qualitative study exploring the skills employers seek in pharmaceutical sciences doctoral graduates

Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4

A novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity

Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?

Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes

Effect of mTOR inhibitors on sodium taurocholate cotransporting polypeptide (NTCP) function in vitro

Species differences in hepatobiliary disposition of taurocholic acid in human and rat sandwich-cultured hepatocytes: implications for drug-induced liver injury

Phase III randomised controlled trial on PSMA PET/CT guided hypofractionated salvage prostate bed radiotherapy of biochemical failure after radical prostatectomy for prostate cancer (PERYTON-trial): study protocol

Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation

Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

A prospective cohort study on the absolute risks of venous thromboembolism and predictive value of screening asymptomatic relatives of patients with hereditary deficiencies of protein S, protein C or antithrombin

Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

Androgen Deprivation therapy for Oligo-recurrent Prostate cancer in addition to radioTherapy (ADOPT): study protocol for a randomised phase III trial

Novel Mechanisms of Valproate Hepatotoxicity: Impaired Mrp2 Trafficking and Hepatocyte Depolarization

A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function

Applicability of somatic monitoring instructions in clinical practice guidelines on antipsychotic drug use

Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation

Predation risk is an ecological constraint for helper dispersal in a cooperatively breeding cichlid

Association of CYP2D6 and CYP2C19 metabolizer status with switching and discontinuing antidepressant drugs: an exploratory study

Mechanistic Modeling of the Hepatic Disposition of Estradiol-17 β -Glucuronide in Sandwich-Cultured Human Hepatocytes

E‑Cigarette Flavoring Chemicals Induce Cytotoxicity in HepG2 Cells

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