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Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

British journal of pharmacology, 1999-11, Vol.128 (6), p.1121-1132

1999

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Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease

Thorax, 2001-01, Vol.56 (1), p.30-35

2001

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Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll‐like receptor 4 responses in macrophages

British journal of pharmacology, 2010-08, Vol.160 (8), p.1997-2007

2010

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In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation

Journal of thrombosis and haemostasis, 2011-03, Vol.9 (3), p.552-561

2011

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Purification and Characterization of Particulate Endothelium-Derived Relaxing Factor Synthase from Cultured and Native Bovine Aortic Endothelial Cells

Proceedings of the National Academy of Sciences - PNAS, 1991-12, Vol.88 (23), p.10480-10484

1991

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Pressor Effects of Circulating Endothelin are Limited by its Removal in the Pulmonary Circulation and by the Release of Prostacyclin and Endothelium-Derived Relaxing Factor

Proceedings of the National Academy of Sciences - PNAS, 1988-12, Vol.85 (24), p.9797-9800

1988

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Ex vivo assay to determine the cyclooxygenase selectivity of non‐steroidal anti‐inflammatory drugs

British journal of pharmacology, 1999-04, Vol.126 (8), p.1824-1830

1999

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Effects of non‐steroidal anti‐inflammatory drugs on cyclo‐oxygenase and lipoxygenase activity in whole blood from aspirin‐sensitive asthmatics vs healthy donors

British journal of pharmacology, 2002-12, Vol.137 (7), p.1031-1038

2002

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Why Neighborhoods (and How We Study Them) Matter for Adolescent Development

Advances in child development and behavior, 2017-01, Vol.52, p.105-152

2017

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Selective COX‐2 inhibitors and human inflammatory bowel disease

Alimentary pharmacology & therapeutics, 1999-08, Vol.13 (8), p.1115-1117

1999

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Platelet responses to pharmacological and physiological interventions in middle‐aged men with different habitual physical activity levels

Acta Physiologica, 2018-05, Vol.223 (1), p.e13028-n/a

2018

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Pharmacological assessment of ibuprofen arginate on platelet aggregation and colon cancer cell killing

Biochemical and biophysical research communications, 2017-03, Vol.484 (4), p.762-766

2017

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Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy

Journal of thrombosis and haemostasis, 2010-03, Vol.8 (3), p.613-615

2010

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Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages

Molecular pharmacology, 1992-04, Vol.41 (4), p.615-624

1992

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Endogenously Released Endothelin-1 from Human Pulmonary Artery Smooth Muscle Promotes Cellular Proliferation . Relevance to Pathogenesis of Pulmonary Hypertension and Vascular Remodeling

American journal of respiratory cell and molecular biology, 2001-07, Vol.25 (1), p.104-110

2001

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Isoforms of nitric oxide synthase Characterization and purification from different cell types

Biochemical pharmacology, 1991-10, Vol.42 (10), p.1849-1857

1991

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A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo‐oxygenase‐2 in vitro and in vivo in a substrate‐sensitive manner

British journal of pharmacology, 1999-08, Vol.127 (7), p.1589-1596

1999

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Insulin Secretion from Pancreatic B Cells Caused by L-Arginine-Derived Nitrogen Oxides

Science (American Association for the Advancement of Science), 1992-02, Vol.255 (5045), p.721-723

1992

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Use of the endothelin antagonists BQ‐123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF

British journal of pharmacology, 1993-10, Vol.110 (2), p.777-782

1993

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Nomenclature for COX-2 Inhibitors

The Lancet (British edition), 2000-10, Vol.356 (9239), p.1373-1374

2000

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Nonsteroid Drug Selectivities for Cyclo-Oxygenase-1 Rather than Cyclo-Oxygenase-2 Are Associated with Human Gastrointestinal Toxicity: A Full in vitro Analysis

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (13), p.7563-7568

1999

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Receptor-Mediated Release of Endothelium-Derived Relaxing Factor and Prostacyclin from Bovine Aortic Endothelial Cells is Coupled

Proceedings of the National Academy of Sciences - PNAS, 1988-04, Vol.85 (7), p.2334-2338

1988

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Expression and Activation of the Farnesoid X Receptor in the Vasculature

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (10), p.3668-3673

2004

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COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs

Nature reviews. Drug discovery, 2006-01, Vol.5 (1), p.75-86

2006

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Aspirin and the in vitro linear relationship between thromboxane A2‐mediated platelet aggregation and platelet production of thromboxane A2

Journal of thrombosis and haemostasis, 2008-11, Vol.6 (11), p.1933-1943

2008

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Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

Sputum and plasma endothelin-1 levels in exacerbations of chronic obstructive pulmonary disease

Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll‐like receptor 4 responses in macrophages

In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation

Purification and Characterization of Particulate Endothelium-Derived Relaxing Factor Synthase from Cultured and Native Bovine Aortic Endothelial Cells

Pressor Effects of Circulating Endothelin are Limited by its Removal in the Pulmonary Circulation and by the Release of Prostacyclin and Endothelium-Derived Relaxing Factor

Ex vivo assay to determine the cyclooxygenase selectivity of non‐steroidal anti‐inflammatory drugs

Effects of non‐steroidal anti‐inflammatory drugs on cyclo‐oxygenase and lipoxygenase activity in whole blood from aspirin‐sensitive asthmatics vs healthy donors

Why Neighborhoods (and How We Study Them) Matter for Adolescent Development

Selective COX‐2 inhibitors and human inflammatory bowel disease

Platelet responses to pharmacological and physiological interventions in middle‐aged men with different habitual physical activity levels

Pharmacological assessment of ibuprofen arginate on platelet aggregation and colon cancer cell killing

Reduction of platelet thromboxane A2 production ex vivo and in vivo by clopidogrel therapy

Regulation and subcellular location of nitrogen oxide synthases in RAW264.7 macrophages

Endogenously Released Endothelin-1 from Human Pulmonary Artery Smooth Muscle Promotes Cellular Proliferation . Relevance to Pathogenesis of Pulmonary Hypertension and Vascular Remodeling

Isoforms of nitric oxide synthase Characterization and purification from different cell types

A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo‐oxygenase‐2 in vitro and in vivo in a substrate‐sensitive manner

Insulin Secretion from Pancreatic B Cells Caused by L-Arginine-Derived Nitrogen Oxides

Use of the endothelin antagonists BQ‐123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF

Nomenclature for COX-2 Inhibitors

Nonsteroid Drug Selectivities for Cyclo-Oxygenase-1 Rather than Cyclo-Oxygenase-2 Are Associated with Human Gastrointestinal Toxicity: A Full in vitro Analysis

Receptor-Mediated Release of Endothelium-Derived Relaxing Factor and Prostacyclin from Bovine Aortic Endothelial Cells is Coupled

Expression and Activation of the Farnesoid X Receptor in the Vasculature

COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs

Aspirin and the in vitro linear relationship between thromboxane A2‐mediated platelet aggregation and platelet production of thromboxane A2

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