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Protocol development to further differentiate and transition stem cell-derived pancreatic progenitors from a monolayer into endocrine cells in suspension culture

Scientific reports, 2023-06, Vol.13 (1), p.8877-8877, Article 8877

2023

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FGF21-Mediated Improvements in Glucose Clearance Require Uncoupling Protein 1

Cell reports (Cambridge), 2015-11, Vol.13 (8), p.1521-1527

2015

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The Role of ARX in Human Pancreatic Endocrine Specification

PloS one, 2015-12, Vol.10 (12), p.e0144100-e0144100

2015

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PDX1+ cell budding morphogenesis in a stem cell-derived islet spheroid system

Nature communications, 2024-07, Vol.15 (1), p.5894-18, Article 5894

2024

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Metabolic switching, growth kinetics and cell yields in the scalable manufacture of stem cell-derived insulin-producing cells

Stem cell research & therapy, 2024-01, Vol.15 (1), p.1-1, Article 1

2024

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Role of myeloid cell leptin signaling in the regulation of glucose metabolism

Scientific reports, 2021-09, Vol.11 (1), p.18394-18394, Article 18394

2021

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Analysis of the effects of bench-scale cell culture platforms and inoculum cell concentrations on PSC aggregate formation and culture

Frontiers in bioengineering and biotechnology, 2023-12, Vol.11, p.1267007-1267007

2023

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AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells

Scientific reports, 2019-07, Vol.9 (1), p.10829-11, Article 10829

2019

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Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice

Cell reports. Medicine, 2021-11, Vol.2 (11), p.100434, Article 100434

2021

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Overexpression of PAX4 reduces glucagon expression in differentiating hESCs

Islets, 2014-01, Vol.6 (2), p.e29236-e29236

2014

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Insulin Null β-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression

Endocrinology (Philadelphia), 2022-06, Vol.163 (6)

2022

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Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture system

Cell reports methods, 2023-05, Vol.3 (5), p.100466-100466, Article 100466

2023

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Leptin contributes to the beneficial effects of insulin treatment in streptozotocin-diabetic male mice

American journal of physiology: endocrinology and metabolism, 2018-12, Vol.315 (6), p.E1264-E1273

2018

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AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects

Scientific reports, 2020-06, Vol.10 (1), p.10518-10518, Article 10518

2020

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Differentiation of Human Pluripotent Stem Cells into Insulin-Producing Islet Clusters

Journal of visualized experiments, 2023-06 (196)

2023

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Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues

Scientific reports, 2019-03, Vol.9 (1), p.3307-3307, Article 3307

2019

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IGFBP2 Is Neither Sufficient nor Necessary for the Physiological Actions of Leptin on Glucose Homeostasis in Male ob/ob Mice

Endocrinology (Philadelphia), 2014-03, Vol.155 (3), p.716-725

2014

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Overexpression of PPARγ Specifically in Pancreatic β-Cells Exacerbates Obesity-Induced Glucose Intolerance, Reduces β-Cell Mass, and Alters Islet Lipid Metabolism in Male Mice

Endocrinology (Philadelphia), 2014-10, Vol.155 (10), p.3843-3852

2014

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SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes

JCI insight, 2020-02, Vol.5 (3)

2020

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Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling

Developmental biology, 2004-04, Vol.268 (2), p.312-326

2004

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Potent Kv1.3 inhibitors from correolide—modification of the C18 position

Bioorganic & medicinal chemistry letters, 2005-01, Vol.15 (2), p.447-451

2005

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Overexpression of peroxisome proliferator‐activated receptor α in pancreatic β‐cells improves glucose tolerance in diet‐induced obese mice

Experimental physiology, 2013-02, Vol.98 (2), p.564-575

2013

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Ephs and ephrins during early stages of chick embryogenesis

Developmental dynamics, 2003-09, Vol.228 (1), p.128-142

2003

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Cellular reprogramming of human amniotic fluid cells to express insulin

Differentiation (London), 2010-09, Vol.80 (2), p.130-139

2010

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Insulin Null [beta]-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression

Endocrinology (Philadelphia), 2022-06, Vol.163 (6), p.1

2022

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Protocol development to further differentiate and transition stem cell-derived pancreatic progenitors from a monolayer into endocrine cells in suspension culture

FGF21-Mediated Improvements in Glucose Clearance Require Uncoupling Protein 1

The Role of ARX in Human Pancreatic Endocrine Specification

PDX1+ cell budding morphogenesis in a stem cell-derived islet spheroid system

Metabolic switching, growth kinetics and cell yields in the scalable manufacture of stem cell-derived insulin-producing cells

Role of myeloid cell leptin signaling in the regulation of glucose metabolism

Analysis of the effects of bench-scale cell culture platforms and inoculum cell concentrations on PSC aggregate formation and culture

AAV GCG-EGFP, a new tool to identify glucagon-secreting α-cells

Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice

Overexpression of PAX4 reduces glucagon expression in differentiating hESCs

Insulin Null β-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression

Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture system

Leptin contributes to the beneficial effects of insulin treatment in streptozotocin-diabetic male mice

AAV8 Ins1-Cre can produce efficient β-cell recombination but requires consideration of off-target effects

Differentiation of Human Pluripotent Stem Cells into Insulin-Producing Islet Clusters

Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues

IGFBP2 Is Neither Sufficient nor Necessary for the Physiological Actions of Leptin on Glucose Homeostasis in Male ob/ob Mice

Overexpression of PPARγ Specifically in Pancreatic β-Cells Exacerbates Obesity-Induced Glucose Intolerance, Reduces β-Cell Mass, and Alters Islet Lipid Metabolism in Male Mice

SNAP23 depletion enables more SNAP25/calcium channel excitosome formation to increase insulin exocytosis in type 2 diabetes

Regulation of Hex gene expression and initial stages of avian hepatogenesis by Bmp and Fgf signaling

Potent Kv1.3 inhibitors from correolide—modification of the C18 position

Overexpression of peroxisome proliferator‐activated receptor α in pancreatic β‐cells improves glucose tolerance in diet‐induced obese mice

Ephs and ephrins during early stages of chick embryogenesis

Cellular reprogramming of human amniotic fluid cells to express insulin

Insulin Null [beta]-cells Have a Prohormone Processing Defect That Is Not Reversed by AAV Rescue of Proinsulin Expression

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