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Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

Journal of medicinal chemistry, 1994-05, Vol.37 (10), p.1385-1401

1994

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Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.2952-2956

1990

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Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library J. Am. Chem. Soc. 1995, 117, 7029−7030

Journal of the American Chemical Society, 1996-01, Vol.118 (3), p.714-714

1996

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Phosphinyl Acid-Based Bisubstrate Analog Inhibitors of Farnesyl Protein Transferase

Journal of medicinal chemistry, 1995-02, Vol.38 (3), p.435-442

1995

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Absolute configuration of 2-amino-4-phenyl butyric acid

Journal of organic chemistry, 1982-10, Vol.47 (21), p.4160-4161

1982

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Phosphorus-containing inhibitors of HMG-CoA reductase. 1. 4-[(2-arylethyl)hydroxyphosphinyl]-3-hydroxy-butanoic acids: a new class of cell-selective inhibitors of cholesterol biosynthesis

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.2952-2956

1990

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C-2 desmethyl seco-mevinic acids. Monocyclic HMG-CoA reductase inbibitors

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (10), p.509-512

1991

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Synthesis of peptide derived amino alcohols II. Synthetic methodology for the preparation of tertiary alcohols

Tetrahedron letters, 1987, Vol.28 (15), p.1603-1606

1987

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Michigan Occupational Information System Final Evaluation Report

Gordon, Eric M

1980

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Monobactams: Ring Activating N-1-Substituents in Monocyclic b-Lactam Antibiotics

Heterocycles, 1984, Vol.21 (1), p.191

1984

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3 - Cephamycin Antibiotics

Penicillins and Cephalosporins, 1982, p.199-370

1982

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Drug Discovery in Africa: Impacts of Genomics, Natural Products, Traditional Medicines, Insights into Medicinal Chemistry, and Technology Platforms in Pursuit of New Drugs

1. Aufl., 2012

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Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

Lancet neurology, 2010, Vol.9 (1), p.67-76

2010

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Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

Nature (London), 2008-05, Vol.453 (7194), p.524-528

2008

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Aftermath: The Clinton Impeachment and the Presidency in the Age of Political Spectacle

1, 2001

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Case Report: Human Tracheal Transplantation Undergoes Progressive Reepithelialization Over Time

The Laryngoscope, 2024-06, Vol.134 (6), p.2664-2671

2024

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An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET

eLife, 2021-10, Vol.10

2021

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Replication Studies of Critical Findings From the Peer Literature: An Introduction

Developmental psychology, 2021-12, Vol.57 (12), p.2007-2010

2021

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Why comply? Farmer motivations and barriers in cannabis agriculture

Journal of rural studies, 2021-08, Vol.86, p.155-170

2021

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Strategic Recruitment Across Borders: An Investigation of Multinational Enterprises

Journal of management, 2019-02, Vol.45 (2), p.476-509

2019

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Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers

Critical care explorations, 2020-10, Vol.2 (10), p.e0272-e0272

2020

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PT-IN-MIND: study protocol for a multisite randomised feasibility trial investigating physical therapy with integrated mindfulness (PT-IN-MIND) for patients with chronic musculoskeletal pain and long-term opioid treatment who attend outpatient physical therapy

BMJ open, 2024-07, Vol.14 (7), p.e082611

2024

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Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation

Critical care explorations, 2020-09, Vol.2 (9), p.e0194-e0194

2020

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Correction: Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

PloS one, 2017-10, Vol.12 (10), p.e0186551-e0186551

2017

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Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis

Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library J. Am. Chem. Soc. 1995, 117, 7029−7030

Phosphinyl Acid-Based Bisubstrate Analog Inhibitors of Farnesyl Protein Transferase

Absolute configuration of 2-amino-4-phenyl butyric acid

Phosphorus-containing inhibitors of HMG-CoA reductase. 1. 4-[(2-arylethyl)hydroxyphosphinyl]-3-hydroxy-butanoic acids: a new class of cell-selective inhibitors of cholesterol biosynthesis

C-2 desmethyl seco-mevinic acids. Monocyclic HMG-CoA reductase inbibitors

Synthesis of peptide derived amino alcohols II. Synthetic methodology for the preparation of tertiary alcohols

Michigan Occupational Information System Final Evaluation Report

Monobactams: Ring Activating N-1-Substituents in Monocyclic b-Lactam Antibiotics

3 - Cephamycin Antibiotics

Drug Discovery in Africa: Impacts of Genomics, Natural Products, Traditional Medicines, Insights into Medicinal Chemistry, and Technology Platforms in Pursuit of New Drugs

Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

Aftermath: The Clinton Impeachment and the Presidency in the Age of Political Spectacle

Case Report: Human Tracheal Transplantation Undergoes Progressive Reepithelialization Over Time

An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET

Replication Studies of Critical Findings From the Peer Literature: An Introduction

Why comply? Farmer motivations and barriers in cannabis agriculture

Strategic Recruitment Across Borders: An Investigation of Multinational Enterprises

Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers

Psilocybin desynchronizes the human brain

PT-IN-MIND: study protocol for a multisite randomised feasibility trial investigating physical therapy with integrated mindfulness (PT-IN-MIND) for patients with chronic musculoskeletal pain and long-term opioid treatment who attend outpatient physical therapy

Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation

Correction: Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

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