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The adverse outcome pathway concept: A pragmatic tool in toxicology

Toxicology (Amsterdam), 2013-10, Vol.312, p.158-165

Vinken, Mathieu

2013

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Establishment of Sandwich Cultures of Primary Human Hepatocytes

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.325

2019

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Adverse outcome pathway from activation of the AhR to breast cancer-related death

Environment international, 2022-07, Vol.165, p.107323-107323, Article 107323

2022

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Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury

Toxicological sciences, 2013-11, Vol.136 (1), p.97-106

2013

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Immortalized Human Hepatic Cell Lines for In Vitro Testing and Research Purposes

Methods in molecular biology (Clifton, N.J.), 2015-01, Vol.1250, p.53

2015

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New approach methodologies in human regulatory toxicology – Not if, but how and when

Environment international, 2023-08, Vol.178, p.108082-108082, Article 108082

2023

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Adverse Outcome Pathways and Drug-Induced Liver Injury Testing

Chemical research in toxicology, 2015-07, Vol.28 (7), p.1391-1397

Vinken, Mathieu

2015

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Toxic talk: pannexin1 channel communication as an emerging mechanism of toxicity

Toxicology (Amsterdam), 2022-08, Vol.478, p.153295-153295, Article 153295

Vinken, Mathieu

2022

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COVID-19 and the liver: an adverse outcome pathway perspective

Toxicology (Amsterdam), 2021-05, Vol.455, p.152765-152765, Article 152765

Vinken, Mathieu

2021

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The Role and Study of Mitochondrial Impairment and Oxidative Stress in Cholestasis

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.117

2019

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Common Bile Duct Ligation as Model for Secondary Biliary Cirrhosis

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.237

2019

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Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory

Frontiers in cellular neuroscience, 2016-12, Vol.10, p.288

2016

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Connexin43 Signaling Contributes to Spontaneous Apoptosis in Cultures of Primary Hepatocytes

Toxicological sciences, 2012-01, Vol.125 (1), p.175-186

2012

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3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Diet: A Rodent Model in Cholestasis Research

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.249

2019

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Taking adverse outcome pathways to the next level

Toxicology in vitro, 2018-08, Vol.50, p.A1-A2

Vinken, Mathieu

2018

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Current insights in the complexities underlying drug-induced cholestasis

Critical reviews in toxicology, 2019-07, Vol.49 (6), p.520-548

2019

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The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation

Toxicology and applied pharmacology, 2013-12, Vol.273 (3), p.484-491

2013

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Culture and Functional Characterization of Human Hepatoma HepG2 Cells

Methods in molecular biology (Clifton, N.J.), 2015-01, Vol.1250, p.77

2015

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A Rotavirus-Induced Mouse Model to Study Biliary Atresia and Neonatal Cholestasis

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.259

2019

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Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.313

2019

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Zebrafish as a Model to Study Cholestatic Liver Diseases

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.273

2019

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Excellence paves the way with Current Research in Toxicology

Current research in toxicology, 2020-06, Vol.1, p.iv-iv

2020

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Primary hepatocyte cultures as in vitro tools for toxicity testing: quo vadis?

Toxicology in vitro, 2012-04, Vol.26 (3), p.541-544

2012

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Mechanisms of Drug-Induced Cholestasis

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.1

2019

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Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies

Methods in molecular biology (Clifton, N.J.), 2019-01, Vol.1981, p.363

2019

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The adverse outcome pathway concept: A pragmatic tool in toxicology

Establishment of Sandwich Cultures of Primary Human Hepatocytes

Adverse outcome pathway from activation of the AhR to breast cancer-related death

Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury

Immortalized Human Hepatic Cell Lines for In Vitro Testing and Research Purposes

New approach methodologies in human regulatory toxicology – Not if, but how and when

Adverse Outcome Pathways and Drug-Induced Liver Injury Testing

Toxic talk: pannexin1 channel communication as an emerging mechanism of toxicity

COVID-19 and the liver: an adverse outcome pathway perspective

The Role and Study of Mitochondrial Impairment and Oxidative Stress in Cholestasis

Common Bile Duct Ligation as Model for Secondary Biliary Cirrhosis

Inhibition of Connexin43 Hemichannels Impairs Spatial Short-Term Memory without Affecting Spatial Working Memory

Connexin43 Signaling Contributes to Spontaneous Apoptosis in Cultures of Primary Hepatocytes

3,5-Diethoxycarbonyl-1,4-Dihydrocollidine Diet: A Rodent Model in Cholestasis Research

Taking adverse outcome pathways to the next level

Current insights in the complexities underlying drug-induced cholestasis

The gap junction inhibitor 2-aminoethoxy-diphenyl-borate protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes and c-jun N-terminal kinase activation

Culture and Functional Characterization of Human Hepatoma HepG2 Cells

A Rotavirus-Induced Mouse Model to Study Biliary Atresia and Neonatal Cholestasis

Organotypic 3D HepaRG Liver Model for Assessment of Drug-Induced Cholestasis

Zebrafish as a Model to Study Cholestatic Liver Diseases

Excellence paves the way with Current Research in Toxicology

Primary hepatocyte cultures as in vitro tools for toxicity testing: quo vadis?

Mechanisms of Drug-Induced Cholestasis

Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies

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