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The Impact of Inherited Retinal Diseases in the United States of America (US) and Canada from a Cost-of-Illness Perspective

Clinical ophthalmology (Auckland, N.Z.), 2021-01, Vol.15, p.2855-2866

2021

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Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

Molecular and cellular neuroscience, 2004-01, Vol.25 (1), p.42-55

2004

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Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-β(42) peptide in vascular dementia

Neuropathology and applied neurobiology, 2006-04, Vol.32 (2), p.103-118

2006

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γ-Secretase Complex Assembly within the Early Secretory Pathway

The Journal of biological chemistry, 2005-02, Vol.280 (8), p.6471-6478

2005

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Differential expression of multiple protein kinase C subspecies in rat central nervous tissue

Biochemical and biophysical research communications, 1987-09, Vol.147 (3), p.911-919

1987

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Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

Proceedings of the National Academy of Sciences - PNAS, 1994-02, Vol.91 (4), p.1470-1474

1994

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The toxicity in vitro of beta-amyloid protein

Biochemical journal, 1995-10, Vol.311 ( Pt 1) (1), p.1-16

1995

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4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.280-284

2006

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Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site

Molecular and cellular neuroscience, 2005-04, Vol.28 (4), p.613-624

2005

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The Intracellular Component of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction Is Specifically Inhibited by β‐Amyloid Peptides

Journal of neurochemistry, 1995-07, Vol.65 (1), p.218-227

1995

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Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ‐secretase activity

Journal of neurochemistry, 2005-09, Vol.94 (5), p.1315-1328

2005

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Quantitation of amyloid-β peptides in biological milieu using a novel homogeneous time-resolved fluorescence (HTRF) assay

Journal of neuroscience methods, 2000-10, Vol.102 (1), p.61-68

2000

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Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor

Neuropharmacology, 2005-06, Vol.48 (7), p.1002-1011

2005

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Fatty acids increase presenilin-1 levels and γ-secretase activity in PSwt-1 cells

Journal of lipid research, 2004-12, Vol.45 (12), p.2368-2376

2004

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Modulation of ion channel activity: a key function of the protein kinase C enzyme family

Pharmacological reviews, 1989-06, Vol.41 (2), p.211

1989

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Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung

Cellular and molecular biology (Noisy-le-Grand, France), 1998-11, Vol.44 (7), p.1147

1998

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Peripheral Arterial Disease and Bypass Surgery in the Diabetic Lower Limb

The Medical clinics of North America, 2013-09, Vol.97 (5), p.821-834

2013

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Novel aspects of accumulation dynamics and Aβ composition in transgenic models of AD

Neurobiology of aging, 2004-10, Vol.25 (9), p.1175-1185

2004

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Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

The Journal of neuroscience, 1988-10, Vol.8 (10), p.3850-3856

1988

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Cerebrospinal fluid levels of β-amyloid(42) in patients with Alzheimerʼs disease are related to the exon 2 polymorphism of the cathepsin D gene

Neuroreport, 2002-07, Vol.13 (10), p.1291-1294

2002

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Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of β-amyloid in rat PC12 cells

Neuroscience letters, 1995-01, Vol.184 (2), p.113-116

1995

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Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion

Neuroscience letters, 1995-09, Vol.197 (3), p.211-214

1995

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Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

FEBS letters, 1989-01, Vol.243 (2), p.177-182

1989

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Peripheral Arterial Disease

Endocrinology and metabolism clinics of North America, 2014-03, Vol.43 (1), p.149-166

2014

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The Impact of Inherited Retinal Diseases in the United States of America (US) and Canada from a Cost-of-Illness Perspective

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-β(42) peptide in vascular dementia

γ-Secretase Complex Assembly within the Early Secretory Pathway

Differential expression of multiple protein kinase C subspecies in rat central nervous tissue

Inhibition of PC12 Cell Redox Activity is a Specific, Early Indicator of the Mechanism of β-Amyloid-Mediated Cell Death

The toxicity in vitro of beta-amyloid protein

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site

The Intracellular Component of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction Is Specifically Inhibited by β‐Amyloid Peptides

Two domains within the first putative transmembrane domain of presenilin 1 differentially influence presenilinase and γ‐secretase activity

Quantitation of amyloid-β peptides in biological milieu using a novel homogeneous time-resolved fluorescence (HTRF) assay

Determination of guinea-pig cortical γ-secretase activity ex vivo following the systemic administration of a γ-secretase inhibitor

Fatty acids increase presenilin-1 levels and γ-secretase activity in PSwt-1 cells

Modulation of ion channel activity: a key function of the protein kinase C enzyme family

Receptor for advanced glycation endproducts (RAGE) exhibits highly differential cellular and subcellular localisation in rat and human lung

Peripheral Arterial Disease and Bypass Surgery in the Diabetic Lower Limb

Novel aspects of accumulation dynamics and Aβ composition in transgenic models of AD

Distinct cellular expression of beta I- and beta II-subspecies of protein kinase C in rat cerebellum

Cerebrospinal fluid levels of β-amyloid(42) in patients with Alzheimerʼs disease are related to the exon 2 polymorphism of the cathepsin D gene

Sulfated glycosaminoglycans and dyes attenuate the neurotoxic effects of β-amyloid in rat PC12 cells

Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion

Selective activation of the γ‐subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites

Peripheral Arterial Disease

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