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RNA circles with minimized immunogenicity as potent PKR inhibitors

Molecular cell, 2022-01, Vol.82 (2), p.420-434.e6

2022

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Insights into the structure and function of the RNA ligase RtcB

Cellular and molecular life sciences : CMLS, 2023-12, Vol.80 (12), p.352-352, Article 352

2023

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Characterization of tRNA splicing enzymes RNA ligase and tRNA 2'-phosphotransferase from the pathogenic fungi Mucorales

RNA (Cambridge), 2024-04, Vol.30 (4), p.367-380

2024

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RNA Repair: Hiding in Plain Sight

Annual review of genetics, 2023-11, Vol.57 (1), p.461-489

Shuman, Stewart

2023

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Chemoproteomic discovery of a human RNA ligase

Nature communications, 2023-02, Vol.14 (1), p.842-842, Article 842

2023

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No-Go Decay mRNA cleavage in the ribosome exit tunnel produces 5'-OH ends phosphorylated by Trl1

Nature communications, 2020-01, Vol.11 (1), p.122-122, Article 122

2020

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Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus

Nucleic acids research, 2024-04, Vol.52 (7), p.3924-3937

2024

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The RtcB RNA ligase is an essential component of the metazoan unfolded protein response

EMBO reports, 2014-12, Vol.15 (12), p.1278-1285

2014

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NAD+-dependent synthesis of a 5'-phospho-ADP-ribosylated RNA/DNA cap by RNA 2'-phosphotransferase Tpt1

Nucleic acids research, 2018-10, Vol.46 (18), p.9617-9624

2018

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In vitro circularization of RNA

RNA biology, 2017-08, Vol.14 (8), p.1018-1027

2017

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RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries

RNA (Cambridge), 2011-09, Vol.17 (9), p.1697-1712

2011

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Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease

Nature communications, 2024-03, Vol.15 (1), p.2378-2378, Article 2378

2024

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Fungi of the order Mucorales express a "sealing-only" tRNA ligase

RNA (Cambridge), 2024-04, Vol.30 (4), p.354-366

2024

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RNA ligase ribozymes with a small catalytic core

Scientific reports, 2023-05, Vol.13 (1), p.8584-8584, Article 8584

2023

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Highly efficient single-stranded DNA ligation technique improves low-input whole-genome bisulfite sequencing by post-bisulfite adaptor tagging

Nucleic acids research, 2019-09, Vol.47 (15), p.e85-e85

2019

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RtcB Is the RNA Ligase Component of an Escherichia coli RNA Repair Operon

The Journal of biological chemistry, 2011-03, Vol.286 (10), p.7727-7731

2011

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Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles

Nucleic acids research, 2019-09, Vol.47 (17), p.8950-8960

2019

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Regulation of Archease by the mTOR-vATPase axis

Development (Cambridge), 2022-10, Vol.149 (19)

2022

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Diversity and roles of (t)RNA ligases

Cellular and molecular life sciences : CMLS, 2012-08, Vol.69 (16), p.2657-2670

2012

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Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex

RNA (Cambridge), 2023-12, Vol.29 (12), p.1856-1869

2023

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RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (16), p.6072-6077

2012

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Viroid RNA redirects host DNA ligase 1 to act as an RNA ligase

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (34), p.13805-13810

2012

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RNA ligation in neurons by RtcB inhibits axon regeneration

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8451-8456

2015

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A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation

Nucleic acids research, 2014-04, Vol.42 (6), p.3931-3942

2014

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Selection and evolution of enzymes from a partially randomized non-catalytic scaffold

Nature (London), 2007-08, Vol.448 (7155), p.828-831

2007

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RNA circles with minimized immunogenicity as potent PKR inhibitors

Insights into the structure and function of the RNA ligase RtcB

Characterization of tRNA splicing enzymes RNA ligase and tRNA 2'-phosphotransferase from the pathogenic fungi Mucorales

RNA Repair: Hiding in Plain Sight

Chemoproteomic discovery of a human RNA ligase

No-Go Decay mRNA cleavage in the ribosome exit tunnel produces 5'-OH ends phosphorylated by Trl1

Characterisation and engineering of a thermophilic RNA ligase from Palaeococcus pacificus

The RtcB RNA ligase is an essential component of the metazoan unfolded protein response

NAD+-dependent synthesis of a 5'-phospho-ADP-ribosylated RNA/DNA cap by RNA 2'-phosphotransferase Tpt1

In vitro circularization of RNA

RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries

Structural and mechanistic insights into activation of the human RNA ligase RTCB by Archease

Fungi of the order Mucorales express a "sealing-only" tRNA ligase

RNA ligase ribozymes with a small catalytic core

Highly efficient single-stranded DNA ligation technique improves low-input whole-genome bisulfite sequencing by post-bisulfite adaptor tagging

RtcB Is the RNA Ligase Component of an Escherichia coli RNA Repair Operon

Systematic minimization of RNA ligase ribozyme through large-scale design-synthesis-sequence cycles

Regulation of Archease by the mTOR-vATPase axis

Diversity and roles of (t)RNA ligases

Thioredoxin regulates the redox state and the activity of the human tRNA ligase complex

RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates

Viroid RNA redirects host DNA ligase 1 to act as an RNA ligase

RNA ligation in neurons by RtcB inhibits axon regeneration

A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation

Selection and evolution of enzymes from a partially randomized non-catalytic scaffold

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