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Orally Absorbed Derivatives of the β‑Lactamase Inhibitor Avibactam. Design of Novel Prodrugs of Sulfate Containing Drugs

Journal of medicinal chemistry, 2018-11, Vol.61 (22), p.10340-10344

2018

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In situ assembly of enzyme inhibitors using extended tethering

Nature biotechnology, 2003-03, Vol.21 (3), p.308-314

2003

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Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

Journal of medicinal chemistry, 1994-05, Vol.37 (10), p.1385-1401

1994

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Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries

Journal of medicinal chemistry, 1994-04, Vol.37 (9), p.1233-1251

1994

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Exercise and rehabilitation of the cancer patient

Urologic oncology, 2008-03, Vol.26 (2), p.204-204

Gordon, Eric M., P.T

2008

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Toward Orally Absorbed Prodrugs of the Antibiotic Aztreonam. Design of Novel Prodrugs of Sulfate Containing Drugs. Part 2

ACS medicinal chemistry letters, 2020-02, Vol.11 (2), p.162-165

2020

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Aminoethylenes: A Tetrahedral Intermediate Isostere Yielding Potent Inhibitors of the Aspartyl Protease BACE-1

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.839-842

2006

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Farnesyl Diphosphate-Based Inhibitors of Ras Farnesyl Protein Transferase

Journal of medicinal chemistry, 1995-07, Vol.38 (15), p.2906-2921

1995

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Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Journal of medicinal chemistry, 2002-11, Vol.45 (23), p.5005-5022

2002

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Innovative approaches to novel antibacterial drug discovery

Current opinion in biotechnology, 1997-12, Vol.8 (6), p.757-762

1997

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Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2804-2815

1991

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Libraries of non-polymeric organic molecules

Current opinion in biotechnology, 1995, Vol.6 (6), p.624-631

Gordon, Eric M

1995

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Hydroxamic Acid-Based Bisubstrate Analog Inhibitors of Ras Farnesyl Protein Transferase

Journal of medicinal chemistry, 1996-10, Vol.39 (21), p.4197-4210

1996

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Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.2952-2956

1990

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Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library J. Am. Chem. Soc. 1995, 117, 7029−7030

Journal of the American Chemical Society, 1996-01, Vol.118 (3), p.714-714

1996

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Applications of small-molecule combinatorial chemistry to drug discovery

Drug discovery today, 1996-04, Vol.1 (4), p.134-144

1996

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Phosphinyl Acid-Based Bisubstrate Analog Inhibitors of Farnesyl Protein Transferase

Journal of medicinal chemistry, 1995-02, Vol.38 (3), p.435-442

1995

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Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells

Oncogene, 1995-05, Vol.10 (9), p.1763-1779

1995

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Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo

The Journal of biological chemistry, 1993-11, Vol.268 (33), p.24832-24837

1993

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Absolute configuration of 2-amino-4-phenyl butyric acid

Journal of organic chemistry, 1982-10, Vol.47 (21), p.4160-4161

1982

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Ras farnesylation as a target for novel antitumor agents: Potent and selective farnesyl diphosphate analog inhibitors of farnesyltransferase

Drug development research, 1995-02, Vol.34 (2), p.121-137

1995

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Phosphorus-containing inhibitors of HMG-CoA reductase. 1. 4-[(2-arylethyl)hydroxyphosphinyl]-3-hydroxy-butanoic acids: a new class of cell-selective inhibitors of cholesterol biosynthesis

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.2952-2956

1990

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C-2 desmethyl seco-mevinic acids. Monocyclic HMG-CoA reductase inbibitors

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (10), p.509-512

1991

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Combinatorial Organic Synthesis: Applications to Drug Discovery

European journal of medicinal chemistry, 1995, Vol.30, p.337s-348s

1995

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Michigan Occupational Information System Final Evaluation Report

Gordon, Eric M

1980

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Orally Absorbed Derivatives of the β‑Lactamase Inhibitor Avibactam. Design of Novel Prodrugs of Sulfate Containing Drugs

In situ assembly of enzyme inhibitors using extended tethering

Applications of Combinatorial Technologies to Drug Discovery. 2. Combinatorial Organic Synthesis, Library Screening Strategies, and Future Directions

Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries

Exercise and rehabilitation of the cancer patient

Toward Orally Absorbed Prodrugs of the Antibiotic Aztreonam. Design of Novel Prodrugs of Sulfate Containing Drugs. Part 2

Aminoethylenes: A Tetrahedral Intermediate Isostere Yielding Potent Inhibitors of the Aspartyl Protease BACE-1

Farnesyl Diphosphate-Based Inhibitors of Ras Farnesyl Protein Transferase

Identification of Potent and Selective Small-Molecule Inhibitors of Caspase-3 through the Use of Extended Tethering and Structure-Based Drug Design

Innovative approaches to novel antibacterial drug discovery

Phosphorus-containing inhibitors of HMG-CoA reductase. 2. Synthesis and biological activities of a series of substituted pyridines containing a hydroxyphosphinyl moiety

Libraries of non-polymeric organic molecules

Hydroxamic Acid-Based Bisubstrate Analog Inhibitors of Ras Farnesyl Protein Transferase

Phosphorus-containing inhibitors of HMG-CoA reductase. I. 4-[(2-Arylethyl)hydroxyphosphinyl]-3-hydroxybutanoic acids: a new class of cell selective inhibitors of cholesterol biosynthesis

Combinatorial Organic Synthesis of Highly Functionalized Pyrrolidines: Identification of a Potent Angiotensin Converting Enzyme Inhibitor from a Mercaptoacyl Proline Library J. Am. Chem. Soc. 1995, 117, 7029−7030

Applications of small-molecule combinatorial chemistry to drug discovery

Phosphinyl Acid-Based Bisubstrate Analog Inhibitors of Farnesyl Protein Transferase

Bisubstrate inhibitors of farnesyltransferase: a novel class of specific inhibitors of ras transformed cells

Lipophilic 1,1-bisphosphonates are potent squalene synthase inhibitors and orally active cholesterol lowering agents in vivo

Absolute configuration of 2-amino-4-phenyl butyric acid

Ras farnesylation as a target for novel antitumor agents: Potent and selective farnesyl diphosphate analog inhibitors of farnesyltransferase

Phosphorus-containing inhibitors of HMG-CoA reductase. 1. 4-[(2-arylethyl)hydroxyphosphinyl]-3-hydroxy-butanoic acids: a new class of cell-selective inhibitors of cholesterol biosynthesis

C-2 desmethyl seco-mevinic acids. Monocyclic HMG-CoA reductase inbibitors

Combinatorial Organic Synthesis: Applications to Drug Discovery

Michigan Occupational Information System Final Evaluation Report

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