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Nickel essentiality, toxicity, and carcinogenicity

Critical reviews in oncology/hematology, 2002-04, Vol.42 (1), p.35-56

2002

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Hypoxic repression of STAT1 and its downstream genes by a pVHL HIF-1 target DEC1 STRA13

Oncogene, 2007-02, Vol.26 (6), p.802-812

2007

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Regulation of hypoxia-inducible genes by ETS1 transcription factor

Carcinogenesis (New York), 2008-08, Vol.29 (8), p.1493-1499

2008

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HIF-1, An Oxygen and Metal Responsive Transcription Factor

Cancer biology & therapy, 2004-01, Vol.3 (1), p.29-35

2004

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α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor

Neuron (Cambridge, Mass.), 1997-06, Vol.18 (6), p.925-937

1997

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Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress

The Journal of biological chemistry, 2004-09, Vol.279 (39), p.40337-40344

2004

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Enhanced expression of a novel protein in human cancer cells: A potential aid to cancer diagnosis

Cell biology and toxicology, 2002-01, Vol.18 (2), p.87-96

2002

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Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

Laboratory investigation, 2005-03, Vol.85 (3), p.328-341

2005

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Loss of thrombospondin transcriptional activity in nickel-transformed cells

Molecular and Cellular Biology, 1994-01, Vol.14 (1), p.851-858

1994

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The Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia

Molecular and Cellular Biology, 2002-03, Vol.22 (6), p.1734-1741

2002

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Ascorbate Depletion: A Critical Step in Nickel Carcinogenesis?

Environmental health perspectives, 2005-05, Vol.113 (5), p.577-584

2005

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Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors

Biochemical and biophysical research communications, 2008-06, Vol.370 (4), p.536-540

2008

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Detection of Changes in Alveolar Macrophage Iron Status Induced by Select PM2.5-Associated Components Using Iron-Response Protein Binding Activity

Inhalation toxicology, 2007-01, Vol.19 (6-7), p.553-562

2007

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The Role of Hypoxia-Inducible Signaling Pathway in Nickel Carcinogenesis

Environmental health perspectives, 2002-10, Vol.110 (suppl 5), p.831-834

2002

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Oxidative stress suppresses transcription factor activities in stimulated lymphocytes

Clinical and experimental immunology, 1998-05, Vol.112 (2), p.242-247

1998

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Cap43, a novel gene specifically induced by Ni2+ compounds

Cancer research (Chicago, Ill.), 1998-05, Vol.58 (10), p.2182-2189

1998

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Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel

Journal of cellular biochemistry, 2006-04, Vol.97 (5), p.1025-1035

2006

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Selective susceptibility of transformed T lymphocytes to induction of apoptosis by PSC 833, an inhibitor of P-glycoprotein

Oncology research, 2001-08, Vol.12 (8), p.315-323

2001

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Effect of nickel and iron co-exposure on human lung cells

Toxicology and applied pharmacology, 2004-04, Vol.196 (2), p.258-265

2004

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Nickel compounds are novel inhibitors of histone H4 acetylation

Cancer research (Chicago, Ill.), 2000-01, Vol.60 (2), p.238-241

2000

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Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel

Molecular pharmacology, 2003-12, Vol.64 (6), p.1485-1493

2003

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Quantum Chemical Modeling of Reaction Mechanism for 2-Oxoglutarate Dependent Enzymes: Effect of Substitution of Iron by Nickel and Cobalt

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2006-03, Vol.110 (12), p.4223-4228

2006

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Molecular Mechanisms in Nickel Carcinogenesis: Modeling Ni(II) Binding Site in Histone H4

Environmental health perspectives, 2002-10, Vol.110 (suppl 5), p.719-723

2002

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Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors

Carcinogenesis (New York), 1999-09, Vol.20 (9), p.1819-1823

1999

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Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer

Cancer research (Chicago, Ill.), 2000-10, Vol.60 (20), p.5630-5634

2000

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Nickel - Toxicity
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Nickel essentiality, toxicity, and carcinogenicity

Hypoxic repression of STAT1 and its downstream genes by a pVHL HIF-1 target DEC1 STRA13

Regulation of hypoxia-inducible genes by ETS1 transcription factor

HIF-1, An Oxygen and Metal Responsive Transcription Factor

α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor

Depletion of Intracellular Ascorbate by the Carcinogenic Metals Nickel and Cobalt Results in the Induction of Hypoxic Stress

Enhanced expression of a novel protein in human cancer cells: A potential aid to cancer diagnosis

Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brain

Loss of thrombospondin transcriptional activity in nickel-transformed cells

The Regulation of Hypoxic Genes by Calcium Involves c-Jun/AP-1, Which Cooperates with Hypoxia-Inducible Factor 1 in Response to Hypoxia

Ascorbate Depletion: A Critical Step in Nickel Carcinogenesis?

Two novel VHL targets, TGFBI (BIGH3) and its transactivator KLF10, are up-regulated in renal clear cell carcinoma and other tumors

Detection of Changes in Alveolar Macrophage Iron Status Induced by Select PM2.5-Associated Components Using Iron-Response Protein Binding Activity

The Role of Hypoxia-Inducible Signaling Pathway in Nickel Carcinogenesis

Oxidative stress suppresses transcription factor activities in stimulated lymphocytes

Cap43, a novel gene specifically induced by Ni2+ compounds

Ascorbate depletion mediates up-regulation of hypoxia-associated proteins by cell density and nickel

Selective susceptibility of transformed T lymphocytes to induction of apoptosis by PSC 833, an inhibitor of P-glycoprotein

Effect of nickel and iron co-exposure on human lung cells

Nickel compounds are novel inhibitors of histone H4 acetylation

Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel

Quantum Chemical Modeling of Reaction Mechanism for 2-Oxoglutarate Dependent Enzymes: Effect of Substitution of Iron by Nickel and Cobalt

Molecular Mechanisms in Nickel Carcinogenesis: Modeling Ni(II) Binding Site in Histone H4

Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors

Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer

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