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Mutational survivorship bias: The case of PNKP

PloS one, 2020-12, Vol.15 (12), p.e0237682-e0237682

2020

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Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro

PloS one, 2014-06, Vol.9 (6), p.e100041

2014

Volltextzugriff (PDF)

Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells

PloS one, 2019-02, Vol.14 (2), p.e0208341

2019

Volltextzugriff (PDF)

Systematic analysis of factors that improve homologous direct repair (HDR) efficiency in CRISPR/Cas9 technique

PloS one, 2021-03, Vol.16 (3), p.e0247603-e0247603

2021

Volltextzugriff (PDF)

An optimized pentaplex PCR for detecting DNA mismatch repair-deficient colorectal cancers

PloS one, 2010-02, Vol.5 (2), p.e9393-e9393

2010

Volltextzugriff (PDF)

Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID

PloS one, 2010-08, Vol.5 (8), p.e12260

2010

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Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutations

PloS one, 2013-10, Vol.8 (10), p.e78500

2013

Volltextzugriff (PDF)

Complex relationship between mismatch repair proteins and MBD4 during immunoglobulin class switch recombination

PloS one, 2013-10, Vol.8 (10), p.e78370-e78370

2013

Volltextzugriff (PDF)

MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1

PloS one, 2010-02, Vol.5 (2), p.e9045

2010

Volltextzugriff (PDF)

Integrated analysis of mismatch repair system in malignant astrocytomas

PloS one, 2013-09, Vol.8 (9), p.e76401-e76401

2013

Volltextzugriff (PDF)

Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage

PloS one, 2020-12, Vol.15 (12), p.e0237759-e0237759

2020

Volltextzugriff (PDF)

Replicative senescence of mesenchymal stem cells: a continuous and organized process

PloS one, 2008-05, Vol.3 (5), p.e2213-e2213

2008

Volltextzugriff (PDF)

Radiosensitization by enzalutamide for human prostate cancer is mediated through the DNA damage repair pathway

PloS one, 2019-04, Vol.14 (4), p.e0214670

2019

Volltextzugriff (PDF)

Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's Sarcoma

PloS one, 2015-10, Vol.10 (10), p.e0140988

2015

Volltextzugriff (PDF)

Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice

PloS one, 2013-11, Vol.8 (11), p.e79543

2013

Volltextzugriff (PDF)

C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation

PloS one, 2021-10, Vol.16 (10), p.e0258269

2021

Volltextzugriff (PDF)

Multiplexed assay of variant effect reveals residues of functional importance in the BRCA1 coiled-coil and serine cluster domains

PloS one, 2023-11, Vol.18 (11), p.e0293422-e0293422

2023

Volltextzugriff (PDF)

Role of caveolin-1 as a biomarker for radiation resistance and tumor aggression in lung cancer

PloS one, 2021-11, Vol.16 (11), p.e0258951-e0258951

2021

Volltextzugriff (PDF)

A critical dose of doxorubicin is required to alter the gene expression profiles in MCF-7 cells acquiring multidrug resistance

PloS one, 2015-01, Vol.10 (1), p.e0116747-e0116747

2015

Volltextzugriff (PDF)

Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation

PloS one, 2020-01, Vol.15 (1), p.e0221681

2020

Volltextzugriff (PDF)

Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability

PloS one, 2017-06, Vol.12 (6), p.e0178450-e0178450

2017

Volltextzugriff (PDF)

Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms

PloS one, 2019-09, Vol.14 (9), p.e0221952

2019

Volltextzugriff (PDF)

Insertional Mutagenesis by CRISPR/Cas9 Ribonucleoprotein Gene Editing in Cells Targeted for Point Mutation Repair Directed by Short Single-Stranded DNA Oligonucleotides

PloS one, 2017-01, Vol.12 (1), p.e0169350

2017

Volltextzugriff (PDF)

Engagement of Components of DNA-Break Repair Complex and NFκB in Hsp70A1A Transcription Upregulation by Heat Shock

PloS one, 2017-01, Vol.12 (1), p.e0168165

2017

Volltextzugriff (PDF)

1 – 25 von 1.193

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Mutational survivorship bias: The case of PNKP

Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro

Fluorescent reporter assays provide direct, accurate, quantitative measurements of MGMT status in human cells

Systematic analysis of factors that improve homologous direct repair (HDR) efficiency in CRISPR/Cas9 technique

An optimized pentaplex PCR for detecting DNA mismatch repair-deficient colorectal cancers

Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID

Expression of the mismatch repair gene hMLH1 is enhanced in non-small cell lung cancer with EGFR mutations

Complex relationship between mismatch repair proteins and MBD4 during immunoglobulin class switch recombination

MutS and MutL are dispensable for maintenance of the genomic mutation rate in the halophilic archaeon Halobacterium salinarum NRC-1

Integrated analysis of mismatch repair system in malignant astrocytomas

Site-specific targeting of a light activated dCas9-KillerRed fusion protein generates transient, localized regions of oxidative DNA damage

Replicative senescence of mesenchymal stem cells: a continuous and organized process

Radiosensitization by enzalutamide for human prostate cancer is mediated through the DNA damage repair pathway

Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's Sarcoma

Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice

C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease

Multiplexed assay of variant effect reveals residues of functional importance in the BRCA1 coiled-coil and serine cluster domains

Role of caveolin-1 as a biomarker for radiation resistance and tumor aggression in lung cancer

A critical dose of doxorubicin is required to alter the gene expression profiles in MCF-7 cells acquiring multidrug resistance

Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation

Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability

Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms

Insertional Mutagenesis by CRISPR/Cas9 Ribonucleoprotein Gene Editing in Cells Targeted for Point Mutation Repair Directed by Short Single-Stranded DNA Oligonucleotides

Engagement of Components of DNA-Break Repair Complex and NFκB in Hsp70A1A Transcription Upregulation by Heat Shock

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