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SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

Science (American Association for the Advancement of Science), 2018-05, Vol.360 (6390), p.800-805

2018

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The IAP family member BRUCE regulates autophagosome-lysosome fusion

Nature communications, 2018-02, Vol.9 (1), p.599-15, Article 599

2018

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Necroptosis microenvironment directs lineage commitment in liver cancer

Nature (London), 2018-10, Vol.562 (7725), p.69-75

2018

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Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

Nature (London), 2015-09, Vol.525 (7570), p.543-547

2015

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Loss-of-function genetic tools for animal models: cross-species and cross-platform differences

Nature reviews. Genetics, 2017-01, Vol.18 (1), p.24

2017

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An Optimized microRNA Backbone for Effective Single-Copy RNAi

Cell reports (Cambridge), 2013-12, Vol.5 (6), p.1704-1713

2013

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Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

Cell host & microbe, 2021-02, Vol.29 (2), p.267-280.e5

2021

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CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

Blood, 2015-01, Vol.125 (1), p.90-101

2015

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EVI1 drives leukemogenesis through aberrant ERG activation

Blood, 2023-02, Vol.141 (5), p.453-466

2023

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BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

Cell reports (Cambridge), 2017-02, Vol.18 (9), p.2162-2174

2017

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ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia

Nature communications, 2023-09, Vol.14 (1), p.5709-5709, Article 5709

2023

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Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters

Nature biotechnology, 2021-02, Vol.39 (2), p.174-178

2021

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Stage-specific control of early B cell development by the transcription factor Ikaros

Nature immunology, 2014-03, Vol.15 (3), p.283

2014

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Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

Genes & development, 2012-01, Vol.26 (2), p.120-125

2012

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Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

Genes & development, 2013-12, Vol.27 (24), p.2648-2662

2013

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CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

Genes & development, 2014-08, Vol.28 (16), p.1800-1814

2014

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MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity

Nature communications, 2018-05, Vol.9 (1), p.1983-16, Article 1983

2018

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The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia

Cancer research (Chicago, Ill.), 2016-03, Vol.76 (5), p.1158-1169

2016

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p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal

Genes & development, 2010-07, Vol.24 (13), p.1389-1402

2010

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Suppression of toxic transgene expression by optimized artificial miRNAs increases AAV vector yields in HEK-293 cells

Molecular therapy. Methods & clinical development, 2024-09, Vol.32 (3), p.101280, Article 101280

2024

Volltextzugriff (PDF)

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

Genes & development, 2011-08, Vol.25 (15), p.1628-1640

2011

Volltextzugriff (PDF)

Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy

EMBO molecular medicine, 2019-08, Vol.11 (8), p.e9266-n/a

2019

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Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

Cell stem cell, 2011-12, Vol.9 (6), p.563-574

2011

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A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells

Scientific reports, 2021-06, Vol.11 (1), p.12973-11, Article 12973

2021

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SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

The IAP family member BRUCE regulates autophagosome-lysosome fusion

Necroptosis microenvironment directs lineage commitment in liver cancer

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

Loss-of-function genetic tools for animal models: cross-species and cross-platform differences

An Optimized microRNA Backbone for Effective Single-Copy RNAi

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation

EVI1 drives leukemogenesis through aberrant ERG activation

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia

Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters

Stage-specific control of early B cell development by the transcription factor Ikaros

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity

The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia

p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal

Suppression of toxic transgene expression by optimized artificial miRNAs increases AAV vector yields in HEK-293 cells

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance

Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy

Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells

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