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Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging

Cell, 2020-07, Vol.182 (1), p.12-23

2020

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Somatic Mutagenesis in Mammals and Its Implications for Human Disease and Aging

Annual review of genetics, 2018-11, Vol.52 (1), p.397-419

2018

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Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (18), p.9014-9019

2019

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Accurate identification of single-nucleotide variants in whole-genome-amplified single cells

Nature methods, 2017-05, Vol.14 (5), p.491-493

2017

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Age-related somatic mutations in the cancer genome

Oncotarget, 2015-09, Vol.6 (28), p.24627-24635

2015

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Deep biomarkers of human aging: Application of deep neural networks to biomarker development

Aging (Albany, NY.), 2016-05, Vol.8 (5), p.1021-1033

2016

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Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging

Genome Biology, 2023-10, Vol.24 (1), p.238-26, Article 238

2023

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Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence

Aging cell, 2017-10, Vol.16 (5), p.1043-1050

2017

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Whole Chromosome Instability induces senescence and promotes SASP

Scientific reports, 2016-10, Vol.6 (1), p.35218-35218, Article 35218

2016

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Genetic evidence for common pathways in human age‐related diseases

Aging cell, 2015-10, Vol.14 (5), p.809-817

2015

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Age-related somatic mutation burden in human tissues

Frontiers in aging, 2022-09, Vol.3, p.1018119-1018119

2022

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In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development

Nature communications, 2016-11, Vol.7 (1), p.13427-13427, Article 13427

2016

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Concurrent analysis of genome and transcriptome in one single cell

BMC research notes, 2024-09, Vol.17 (1), p.267-6, Article 267

2024

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Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers

The Journal of clinical investigation, 2022-03, Vol.132 (5), p.1-6

2022

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Polygenic prediction of human longevity on the supposition of pervasive pleiotropy

Scientific reports, 2024-08, Vol.14 (1), p.19981-19, Article 19981

2024

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Judith Campisi (1948–2024), cell biologist who explored how cells age

Nature (London), 2024-03, Vol.627 (8002), p.29-29

2024

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Obituary: Judith Campisi (1948–2024)

Nature (London), 2024-03, Vol.627 (8002), p.29-29

2024

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Evidence for a limit to human lifespan

Nature (London), 2016-10, Vol.538 (7624), p.257-259

2016

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SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing

Frontiers in genetics, 2020-11, Vol.11, p.505441-505441

2020

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Genome-wide, Single-Cell DNA Methylomics Reveals Increased Non-CpG Methylation during Human Oocyte Maturation

Stem cell reports, 2017-07, Vol.9 (1), p.397-407

2017

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Genetic wrinkles in time

Nature reviews. Molecular cell biology, 2023-12, Vol.24 (12), p.856-856

2023

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Aging of the eye: Lessons from cataracts and age-related macular degeneration

Ageing research reviews, 2024-08, Vol.99, p.102407, Article 102407

2024

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Radiation damage in male worms skips a generation

Nature (London), 2023-01, Vol.613 (7943), p.1-2

2023

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A mechanism for inheriting radiation-induced DNA damage

Nature (London), 2023-01, Vol.613 (7943), p.249-250

2023

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Editorial: Somatic mutations, genome mosaicism and aging

Frontiers in aging, 2022, Vol.3, p.1115408-1115408

2022

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Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging

Somatic Mutagenesis in Mammals and Its Implications for Human Disease and Aging

Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

Accurate identification of single-nucleotide variants in whole-genome-amplified single cells

Age-related somatic mutations in the cancer genome

Deep biomarkers of human aging: Application of deep neural networks to biomarker development

Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging

Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence

Whole Chromosome Instability induces senescence and promotes SASP

Genetic evidence for common pathways in human age‐related diseases

Age-related somatic mutation burden in human tissues

In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development

Concurrent analysis of genome and transcriptome in one single cell

Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers

Polygenic prediction of human longevity on the supposition of pervasive pleiotropy

Judith Campisi (1948–2024), cell biologist who explored how cells age

Obituary: Judith Campisi (1948–2024)

Evidence for a limit to human lifespan

SCCNV: A Software Tool for Identifying Copy Number Variation From Single-Cell Whole-Genome Sequencing

Genome-wide, Single-Cell DNA Methylomics Reveals Increased Non-CpG Methylation during Human Oocyte Maturation

Genetic wrinkles in time

Aging of the eye: Lessons from cataracts and age-related macular degeneration

Radiation damage in male worms skips a generation

A mechanism for inheriting radiation-induced DNA damage

Editorial: Somatic mutations, genome mosaicism and aging

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