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Mechanism-based pharmacokinetic-pharmacodynamic modeling-a new classification of biomarkers

Pharmaceutical research, 2005-09, Vol.22 (9), p.1432-1437

2005

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Population pharmacokinetics–pharmacodynamics of alemtuzumab (Campath®) in patients with chronic lymphocytic leukaemia and its link to treatment response

British journal of clinical pharmacology, 2007-09, Vol.64 (3), p.278-291

2007

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Correlation of genotype, phenotype, and mRNA expression of CYP2D6 and CYP2C19 in peripheral blood leukocytes (PBLs)

International journal of clinical pharmacology and therapeutics, 2014-02, Vol.52 (2), p.143-150

2014

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Clinical-pharmacological stratégies to assess drug interaction potential during drug development

Drug safety, 2001, Vol.24 (10), p.715-725

2001

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Alternative strategies in drug development: clinical pharmacological aspects

International journal of clinical pharmacology and therapeutics, 1999-12, Vol.37 (12), p.575

Kuhlmann, J

1999

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A generic building block for C- and N-terminal protein-labeling and protein-immobilization

Bioorganic & medicinal chemistry, 2006-09, Vol.14 (18), p.6288-6306

2006

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Adverse events in volunteers participating in phase I clinical trials: a single-center five-year survey in 1,559 subjects

International journal of clinical pharmacology and therapeutics, 2005-05, Vol.43 (5), p.217-226

2005

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The influence of valerian treatment on reaction time, alertness and concentration in volunteers

Pharmacopsychiatry, 1999-11, Vol.32 (6), p.235-241

1999

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Glucuronidation of acetaminophen is independent of UGT1A1 promotor genotype

International journal of clinical pharmacology and therapeutics, 2004-02, Vol.42 (2), p.73-77

2004

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Influence of erythromycin pre- and co-treatment on single-dose pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin

European journal of clinical pharmacology, 1998-02, Vol.53 (6), p.469-473

1998

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Human pharmacology -- clinical pharmacology. Common goals and tasks from the point of view of the DGPT Section Clinical Pharmacology (German society of experimental and clinical Pharmacology and Toxicology)

International journal of clinical pharmacology and therapeutics, 1998-11, Vol.36 (11), p.576

Kuhlmann, J

1998

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Pharmacokinetics of ciprofloxacin in pediatric cystic fibrosis patients

Antimicrobial Agents and Chemotherapy, 1996-01, Vol.40 (1), p.29-34

1996

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When Are Bioavailability Studies Required? A German Proposal

Journal of clinical pharmacology, 1998-10, Vol.38 (10), p.904-911

1998

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Effects of nifedipine and diltiazem on plasma levels and renal excretion of beta-acetyldigoxin

Clinical pharmacology and therapeutics, 1985-02, Vol.37 (2), p.150-156

Kuhlmann, J

1985

Volltextzugriff (PDF)

Predicting the risk of sporadic elevated bilirubin levels and diagnosing Gilbert's syndrome by genotyping UGT1A128 promoter polymorphism

International journal of clinical pharmacology and therapeutics, 2002-06, Vol.40 (6), p.233-240

2002

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Grapefruit juice increases oral nimodipine bioavailability

International journal of clinical pharmacology and therapeutics, 1998-03, Vol.36 (3), p.126

1998

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Absolute and relative bioavailability of the HMG-CoA reductase inhibitor cerivastatin

International journal of clinical pharmacology and therapeutics, 1997-06, Vol.35 (6), p.255

1997

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Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin

Clinical pharmacology and therapeutics, 1985-12, Vol.38 (6), p.667-673

Kuhlmann, J

1985

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Guidances related to bioavailability and bioequivalence : European industry perspective

European journal of drug metabolism and pharmacokinetics, 2000-01, Vol.25 (1), p.25-27

2000

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Monitoring of proteinuria in phase I studies in healthy male subjects

European journal of clinical pharmacology, 1998-06, Vol.54 (4), p.287-294

1998

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Pharmacokinetic-pharmacodynamic modelling as a tool to evaluate the clinical relevance of a drug-food interaction for a nisoldipine controlled-release dosage form

European journal of clinical pharmacology, 1997, Vol.51 (6), p.473-480

1997

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Pharmacodynamics and pharmacokinetics of BAY x 7195 aerosol, a new and selective receptor antagonist of cysteinyl‐leukotrienes, in normal volunteers

British journal of clinical pharmacology, 1996-08, Vol.42 (2), p.171-178

1996

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Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients

Clinical pharmacology and therapeutics, 1999-03, Vol.65 (3), p.251-261

1999

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Influence of cholestyramine on the pharmacokinetics of cerivastatin

International journal of clinical pharmacology and therapeutics, 1997-06, Vol.35 (6), p.250

1997

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The influence of age on the pharmacokinetics of nimodipine

International journal of clinical pharmacology and therapeutics, 1996-07, Vol.34 (7), p.293

1996

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Mechanism-based pharmacokinetic-pharmacodynamic modeling-a new classification of biomarkers

Population pharmacokinetics–pharmacodynamics of alemtuzumab (Campath®) in patients with chronic lymphocytic leukaemia and its link to treatment response

Correlation of genotype, phenotype, and mRNA expression of CYP2D6 and CYP2C19 in peripheral blood leukocytes (PBLs)

Clinical-pharmacological stratégies to assess drug interaction potential during drug development

Alternative strategies in drug development: clinical pharmacological aspects

A generic building block for C- and N-terminal protein-labeling and protein-immobilization

Adverse events in volunteers participating in phase I clinical trials: a single-center five-year survey in 1,559 subjects

The influence of valerian treatment on reaction time, alertness and concentration in volunteers

Glucuronidation of acetaminophen is independent of UGT1A1 promotor genotype

Influence of erythromycin pre- and co-treatment on single-dose pharmacokinetics of the HMG-CoA reductase inhibitor cerivastatin

Human pharmacology -- clinical pharmacology. Common goals and tasks from the point of view of the DGPT Section Clinical Pharmacology (German society of experimental and clinical Pharmacology and Toxicology)

Pharmacokinetics of ciprofloxacin in pediatric cystic fibrosis patients

When Are Bioavailability Studies Required? A German Proposal

Effects of nifedipine and diltiazem on plasma levels and renal excretion of beta-acetyldigoxin

Predicting the risk of sporadic elevated bilirubin levels and diagnosing Gilbert's syndrome by genotyping UGT1A128 promoter polymorphism

Grapefruit juice increases oral nimodipine bioavailability

Absolute and relative bioavailability of the HMG-CoA reductase inhibitor cerivastatin

Effects of verapamil, diltiazem, and nifedipine on plasma levels and renal excretion of digitoxin

Guidances related to bioavailability and bioequivalence : European industry perspective

Monitoring of proteinuria in phase I studies in healthy male subjects

Pharmacokinetic-pharmacodynamic modelling as a tool to evaluate the clinical relevance of a drug-food interaction for a nisoldipine controlled-release dosage form

Pharmacodynamics and pharmacokinetics of BAY x 7195 aerosol, a new and selective receptor antagonist of cysteinyl‐leukotrienes, in normal volunteers

Increase in cerivastatin systemic exposure after single and multiple dosing in cyclosporine-treated kidney transplant recipients

Influence of cholestyramine on the pharmacokinetics of cerivastatin

The influence of age on the pharmacokinetics of nimodipine

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