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Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Cell, 2012-08, Vol.150 (5), p.895-908

2012

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Gene Expression by Mouse Inner Ear Hair Cells during Development

The Journal of neuroscience, 2015-04, Vol.35 (16), p.6366-6380

2015

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TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells

Neuron (Cambridge, Mass.), 2018-08, Vol.99 (4), p.736-753.e6

2018

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High levels of AAV vector integration into CRISPR-induced DNA breaks

Nature communications, 2019-09, Vol.10 (1), p.4439-11, Article 4439

2019

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Structure of a force―conveying cadherin bond essential for inner―ear mechanotransduction

Nature (London), 2012-12, Vol.492 (7427), p.128-132

2012

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Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?

The Journal of neuroscience, 2016-10, Vol.36 (43), p.10921-10926

2016

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Finding a window for gene therapy for hereditary deafness

Proceedings of the National Academy of Sciences - PNAS, 2023-09, Vol.120 (39), p.e2311864120

2023

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Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV

Molecular therapy, 2017-02, Vol.25 (2), p.379-391

2017

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PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing

Nature communications, 2019-08, Vol.10 (1), p.3801-3801, Article 3801

2019

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Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F

Nature communications, 2023-04, Vol.14 (1), p.2400-2400, Article 2400

2023

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C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells

Stem cell reports, 2015-01, Vol.4 (1), p.47-60

2015

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Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

Nature medicine, 2019-07, Vol.25 (7), p.1123-1130

2019

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TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

The Journal of neuroscience, 2009-04, Vol.29 (15), p.4808-4819

2009

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Structural Determinants of Cadherin-23 Function in Hearing and Deafness

Neuron (Cambridge, Mass.), 2010-04, Vol.66 (1), p.85-100

2010

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Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection

Nature communications, 2021-02, Vol.12 (1), p.849-849, Article 849

2021

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Regulation of TFEB and V-ATPases by mTORC1

The EMBO journal, 2011-08, Vol.30 (16), p.3242-3258

2011

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Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins

Nature communications, 2015-04, Vol.6 (1), p.6855-6855, Article 6855

2015

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Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

Nature (London), 2012-01, Vol.481 (7382), p.520-524

2012

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Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs

Nature biotechnology, 2009-05, Vol.27 (5), p.478-484

2009

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Difficulties translating antisense-mediated activation of Frataxin expression from cell culture to mice

RNA biology, 2022-12, Vol.19 (1), p.364-372

2022

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The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

Gastroenterology (New York, N.Y. 1943), 2009-12, Vol.137 (6), p.2084-2095.e3

2009

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An Ion Channel Essential for Sensing Chemical Damage

The Journal of neuroscience, 2007-10, Vol.27 (42), p.11412-11415

2007

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Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear

Nature communications, 2015-04, Vol.6 (1), p.6873-6873, Article 6873

2015

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Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F

Molecular therapy, 2023-08, Vol.31 (8), p.2439-2453

2023

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Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice

PloS one, 2016-05, Vol.11 (5), p.e0155577-e0155577

2016

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Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Gene Expression by Mouse Inner Ear Hair Cells during Development

TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells

High levels of AAV vector integration into CRISPR-induced DNA breaks

Structure of a force―conveying cadherin bond essential for inner―ear mechanotransduction

Are TMCs the Mechanotransduction Channels of Vertebrate Hair Cells?

Finding a window for gene therapy for hereditary deafness

Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV

PKHD1L1 is a coat protein of hair-cell stereocilia and is required for normal hearing

Mini-PCDH15 gene therapy rescues hearing in a mouse model of Usher syndrome type 1F

C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cells

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons

Structural Determinants of Cadherin-23 Function in Hearing and Deafness

Single-molecule force spectroscopy reveals the dynamic strength of the hair-cell tip-link connection

Regulation of TFEB and V-ATPases by mTORC1

Length regulation of mechanosensitive stereocilia depends on very slow actin dynamics and filament-severing proteins

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia

Allele-specific silencing of mutant huntingtin and ataxin-3 genes by targeting expanded CAG repeats in mRNAs

Difficulties translating antisense-mediated activation of Frataxin expression from cell culture to mice

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

An Ion Channel Essential for Sensing Chemical Damage

Live-cell imaging of actin dynamics reveals mechanisms of stereocilia length regulation in the inner ear

Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F

Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice

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