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Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs

Nucleic acids research, 2018-02, Vol.46 (4), p.1584-1600

2018

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Reexamining assumptions about miRNA-guided gene silencing

Nucleic acids research, 2022-01, Vol.50 (2), p.617-634

2022

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The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy

Nucleic acid therapeutics, 2020-04, Vol.30 (2), p.67-70

2020

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Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Cell, 2012-08, Vol.150 (5), p.895-908

2012

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Regulation of mammalian transcription and splicing by Nuclear RNAi

Nucleic acids research, 2016-01, Vol.44 (2), p.524-537

2016

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Targeting RNA with synthetic oligonucleotides: Clinical success invites new challenges

Cell chemical biology, 2024-01, Vol.31 (1), p.125-138

2024

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Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading

Nature protocols, 2014-09, Vol.9 (9), p.2045-2060

2014

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Challenges and Opportunities for Nucleic Acid Therapeutics

Nucleic acid therapeutics, 2022-02, Vol.32 (1), p.8-13

2022

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The Requirement for GW182 Scaffolding Protein Depends on Whether Argonaute Is Mediating Translation, Transcription, or Splicing

Biochemistry (Easton), 2018-09, Vol.57 (35), p.5247-5256

2018

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Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

Nucleic acids research, 2011-07, Vol.39 (13), p.5682-5691

2011

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RNAi in cell nuclei: potential for a new layer of biological regulation and a new strategy for therapeutic discovery

RNA (Cambridge), 2023-04, Vol.29 (4), p.415-422

2023

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RNA sequencing: platform selection, experimental design, and data interpretation

Nucleic acid therapeutics, 2012-08, Vol.22 (4), p.271-274

2012

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Argonaute binding within 3'-untranslated regions poorly predicts gene repression

Nucleic acids research, 2020-07, Vol.48 (13), p.7439

2020

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Promoter RNA links transcriptional regulation of inflammatory pathway genes

Nucleic acids research, 2013-12, Vol.41 (22), p.10086-10109

2013

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Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs

Nucleic acids research, 2024-02, Vol.52 (4), p.1930-1952

2024

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Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing

RNA (Cambridge), 2021-09, Vol.27 (9), p.1004-1016

2021

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Argonaute binding within human nuclear RNA and its impact on alternative splicing

RNA (Cambridge), 2021-09, Vol.27 (9), p.991-1003

2021

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Editorial: Nucleic Acids Research virtual issue dedicated to nucleic acid therapeutics, 2018-2023

Nucleic acids research, 2024-01, Vol.52 (2), p.511-512

2024

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Editorial: Critical reviews and perspectives in Nucleic Acids Research

Nucleic acids research, 2022-07, Vol.50 (13), p.7201-7201

2022

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Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing

Nucleic acids research, 2012-02, Vol.40 (3), p.1240-1250

2012

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Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression

Nucleic acids research, 2021-11, Vol.49 (20), p.11560-11574

2021

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Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells

RNA (Cambridge), 2016-07, Vol.22 (7), p.1085-1098

2016

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Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

Nature medicine, 2019-07, Vol.25 (7), p.1123-1130

2019

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Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

Nucleic acids research, 2010-11, Vol.38 (21), p.7736-7748

2010

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RNA-Mediated Gene Activation: Identifying a Candidate RNA for Preclinical Development

RNA Activation, 2017, p.161-171

2017

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Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs

Reexamining assumptions about miRNA-guided gene silencing

The 10th Oligonucleotide Therapy Approved: Golodirsen for Duchenne Muscular Dystrophy

Single-Stranded RNAs Use RNAi to Potently and Allele-Selectively Inhibit Mutant Huntingtin Expression

Regulation of mammalian transcription and splicing by Nuclear RNAi

Targeting RNA with synthetic oligonucleotides: Clinical success invites new challenges

Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading

Challenges and Opportunities for Nucleic Acid Therapeutics

The Requirement for GW182 Scaffolding Protein Depends on Whether Argonaute Is Mediating Translation, Transcription, or Splicing

Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

RNAi in cell nuclei: potential for a new layer of biological regulation and a new strategy for therapeutic discovery

RNA sequencing: platform selection, experimental design, and data interpretation

Argonaute binding within 3'-untranslated regions poorly predicts gene repression

Promoter RNA links transcriptional regulation of inflammatory pathway genes

Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing

Argonaute binding within human nuclear RNA and its impact on alternative splicing

Editorial: Nucleic Acids Research virtual issue dedicated to nucleic acid therapeutics, 2018-2023

Editorial: Critical reviews and perspectives in Nucleic Acids Research

Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing

Targeting 3' and 5' untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression

Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells

Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

RNA-Mediated Gene Activation: Identifying a Candidate RNA for Preclinical Development

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