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Lessons from gain‐ and loss‐of‐function models of pro‐survival Bcl2 family proteins: implications for targeted therapy

The FEBS journal, 2015-03, Vol.282 (5), p.834-849

2015

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CRISPR/Cas9‐mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse

EMBO molecular medicine, 2016-05, Vol.8 (5), p.477-488

2016

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Targeting macrophages in the tumour environment to enhance the efficacy of αOX40 therapy

Immunology, 2012-08, Vol.136 (4), p.437-447

2012

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Sirtuin 3‐mediated deacetylation of acyl‐CoA synthetase family member 3 by protocatechuic acid attenuates non‐alcoholic fatty liver disease

British journal of pharmacology, 2020-09, Vol.177 (18), p.4166-4180

2020

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Prevention of Cholestatic Liver Disease and Reduced Tumorigenicity in a Murine Model of PFIC Type 3 Using Hybrid AAV‐piggyBac Gene Therapy

Hepatology (Baltimore, Md.), 2019-12, Vol.70 (6), p.2047-2061

2019

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Janus Family kinase (JAK) inhibitors in HLH and severe COVID‐19

American journal of hematology, 2020-12, Vol.95 (12), p.1448-1451

Wilcox, Ryan A.

2020

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The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

Clinical and experimental immunology, 2011-10, Vol.166 (1), p.1-15

2011

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Identification of four TMC 1 variations in different Chinese families with hereditary hearing loss

Molecular genetics & genomic medicine, 2018-07, Vol.6 (4), p.504-513

2018

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NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma

Journal of leukocyte biology, 2020-09, Vol.108 (3), p.937-952

2020

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Targeting microglial NLRP3 in the SNc region as a promising disease‐modifying therapy for Parkinson's disease

Brain and behavior, 2022-11, Vol.12 (11), p.e2784-n/a

2022

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Evolution of GCGR family ligand-receptor extensive cross-interaction systems suggests a therapeutic direction for hyperglycemia in mammals

Acta biochimica et biophysica Sinica, 2023-12, Vol.55 (12), p.1855-1863

2023

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Treatment of Retinoblastoma 1–Intact Hepatocellular Carcinoma With Cyclin‐Dependent Kinase 4/6 Inhibitor Combination Therapy

Hepatology (Baltimore, Md.), 2021-10, Vol.74 (4), p.1971-1993

2021

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Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug‐refractory epilepsy

Epilepsia (Copenhagen), 2017-09, Vol.58 (9), p.1603-1614

2017

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Targets for Ibrutinib Beyond B Cell Malignancies

Scandinavian journal of immunology, 2015-09, Vol.82 (3), p.208-217

2015

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NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Hepatology (Baltimore, Md.), 2014-03, Vol.59 (3), p.898-910

2014

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Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway

Journal of cellular and molecular medicine, 2017-11, Vol.21 (11), p.2937-2949

2017

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Suppression of innate inflammation and immunity by interleukin‐37

European journal of immunology, 2016-05, Vol.46 (5), p.1067-1081

2016

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Identification of four TMC1 variations in different Chinese families with hereditary hearing loss

Molecular genetics & genomic medicine, 2018-07, Vol.6 (4), p.504-513

2018

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Pharmacological therapies for Angelman syndrome

Wiener medizinische Wochenschrift, 2017-06, Vol.167 (9-10), p.205-218

2017

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Baicalin mitigates cognitive impairment and protects neurons from microglia‐mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF‐κB signaling pathway

CNS neuroscience & therapeutics, 2019-05, Vol.25 (5), p.575-590

2019

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Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways

Acta pharmacologica Sinica, 2022-05, Vol.43 (5), p.1324-1336

2022

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GLI family zinc finger protein 2 promotes skin fibroblast proliferation and DNA damage repair by targeting the miR‐200/ataxia telangiectasia mutated axis in diabetic wound healing

The Kaohsiung journal of medical sciences, 2024-05, Vol.40 (5), p.422-434

2024

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The role of the microbiome and the NLRP3 inflammasome in the gut and lung

Journal of leukocyte biology, 2020-09, Vol.108 (3), p.925-935

2020

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TNF promotes DECTIN2 family C-type lectin receptor expression in human macrophages

Journal of leukocyte biology, 2023-06, Vol.113 (6), p.615-625

2023

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Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice

CNS neuroscience & therapeutics, 2022-03, Vol.28 (3), p.390-400

2022

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Lessons from gain‐ and loss‐of‐function models of pro‐survival Bcl2 family proteins: implications for targeted therapy

CRISPR/Cas9‐mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse

Targeting macrophages in the tumour environment to enhance the efficacy of αOX40 therapy

Sirtuin 3‐mediated deacetylation of acyl‐CoA synthetase family member 3 by protocatechuic acid attenuates non‐alcoholic fatty liver disease

Prevention of Cholestatic Liver Disease and Reduced Tumorigenicity in a Murine Model of PFIC Type 3 Using Hybrid AAV‐piggyBac Gene Therapy

Janus Family kinase (JAK) inhibitors in HLH and severe COVID‐19

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

Identification of four TMC 1 variations in different Chinese families with hereditary hearing loss

NLRP3 inflammasome priming: A riddle wrapped in a mystery inside an enigma

Targeting microglial NLRP3 in the SNc region as a promising disease‐modifying therapy for Parkinson's disease

Evolution of GCGR family ligand-receptor extensive cross-interaction systems suggests a therapeutic direction for hyperglycemia in mammals

Treatment of Retinoblastoma 1–Intact Hepatocellular Carcinoma With Cyclin‐Dependent Kinase 4/6 Inhibitor Combination Therapy

Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug‐refractory epilepsy

Targets for Ibrutinib Beyond B Cell Malignancies

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Nintedanib reduces ventilation‐augmented bleomycin‐induced epithelial–mesenchymal transition and lung fibrosis through suppression of the Src pathway

Suppression of innate inflammation and immunity by interleukin‐37

Identification of four TMC1 variations in different Chinese families with hereditary hearing loss

Pharmacological therapies for Angelman syndrome

Baicalin mitigates cognitive impairment and protects neurons from microglia‐mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF‐κB signaling pathway

Gout-associated monosodium urate crystal-induced necrosis is independent of NLRP3 activity but can be suppressed by combined inhibitors for multiple signaling pathways

GLI family zinc finger protein 2 promotes skin fibroblast proliferation and DNA damage repair by targeting the miR‐200/ataxia telangiectasia mutated axis in diabetic wound healing

The role of the microbiome and the NLRP3 inflammasome in the gut and lung

TNF promotes DECTIN2 family C-type lectin receptor expression in human macrophages

Electroacupuncture ameliorates postoperative cognitive dysfunction and associated neuroinflammation via NLRP3 signal inhibition in aged mice

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