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Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes

Journal of controlled release, 2014-03, Vol.178, p.101-107

2014

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Enhanced Tumor Uptake and Penetration of Virotherapy Using Polymer Stealthing and Focused Ultrasound

JNCI : Journal of the National Cancer Institute, 2013-11, Vol.105 (22), p.1701-1710

2013

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Cavitation-Enhanced Extravasation for Drug Delivery

Ultrasound in medicine & biology, 2011-11, Vol.37 (11), p.1838-1852

2011

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Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound

Journal of controlled release, 2013-07, Vol.169 (1-2), p.40-47

2013

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VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects

Journal for immunotherapy of cancer, 2021-11, Vol.9 (11), p.e003254

2021

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Hyaluronidase expression within tumors increases virotherapy efficacy and T cell accumulation

Molecular therapy. Oncolytics, 2021-09, Vol.22, p.27-35

2021

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Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness

International journal of molecular sciences, 2020-07, Vol.21 (14), p.5158

2020

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Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells

PLoS pathogens, 2009-05, Vol.5 (5), p.e1000440-e1000440

2009

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MEN1 Gene Replacement Therapy Reduces Proliferation Rates in a Mouse Model of Pituitary Adenomas

Cancer research (Chicago, Ill.), 2012-10, Vol.72 (19), p.5060-5068

2012

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A non-exothermic cell-embedding tissue-mimicking material for studies of ultrasound-induced hyperthermia and drug release

International journal of hyperthermia, 2013-01, Vol.29 (2), p.133-144

2013

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Real-time optical measurement of biologically relevant thermal damage in tissue-mimicking hydrogels containing bovine serum albumin

International journal of hyperthermia, 2010-01, Vol.26 (5), p.456-464

2010

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Evolving Status of Clinical Immunotherapy with Oncolytic Adenovirus

Clinical cancer research, 2021-06, Vol.27 (11), p.2979-2988

2021

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Role of brain-derived neurotrophic factor in the protective action of N-methyl-D-aspartate in the apoptotic death of cerebellar granule neurons induced by low potassium

Journal of neuroscience research, 2007-02, Vol.85 (2), p.332-341

2007

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Evaluation of THEO-260 as a novel oncolytic virus therapy for treating stromal rich tumours

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.e14573-e14573

2023

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Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression

Clinical cancer research, 2015-03, Vol.21 (6), p.1406-1418

2015

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Cavitation-enhanced delivery of macromolecules into an obstructed vessel

The Journal of the Acoustical Society of America, 2010-11, Vol.128 (5), p.EL310-EL315

2010

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Oncolytic adenovirus with hyaluronidase activity that evades neutralizing antibodies: VCN-11

Journal of controlled release, 2021-04, Vol.332, p.517-528

2021

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Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01

Science translational medicine, 2019-01, Vol.11 (476)

2019

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Inhibition of Delta-Like-4–Mediated Signaling Impairs Reparative Angiogenesis After Ischemia

Circulation research, 2010-07, Vol.107 (2), p.283-293

2010

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Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model

Journal of controlled release, 2012-01, Vol.157 (2), p.235-242

2012

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Adenovirus Type 5 Interactions with Human Blood Cells May Compromise Systemic Delivery

Molecular therapy, 2006-07, Vol.14 (1), p.118-128

2006

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Use of micro- and nano-sized inertial cavitation nuclei to trigger and map drug release from cavitation-sensitive liposomes

The Journal of the Acoustical Society of America, 2013-11, Vol.134 (5_Supplement), p.4050-4050

2013

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Active Adenoviral Vascular Penetration by Targeted Formation of Heterocellular Endothelial–epithelial Syncytia

Molecular therapy, 2011-01, Vol.19 (1), p.67-75

2011

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Exploitation of cavitation-enhanced heating for release of doxorubicin from thermosensitve liposomes by therapeutic ultrasound

The Journal of the Acoustical Society of America, 2010-10, Vol.128 (4_Supplement), p.2418-2418

2010

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Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes

Enhanced Tumor Uptake and Penetration of Virotherapy Using Polymer Stealthing and Focused Ultrasound

Cavitation-Enhanced Extravasation for Drug Delivery

Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound

VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects

Hyaluronidase expression within tumors increases virotherapy efficacy and T cell accumulation

Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors

Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness

Use of tissue-specific microRNA to control pathology of wild-type adenovirus without attenuation of its ability to kill cancer cells

MEN1 Gene Replacement Therapy Reduces Proliferation Rates in a Mouse Model of Pituitary Adenomas

A non-exothermic cell-embedding tissue-mimicking material for studies of ultrasound-induced hyperthermia and drug release

Real-time optical measurement of biologically relevant thermal damage in tissue-mimicking hydrogels containing bovine serum albumin

Evolving Status of Clinical Immunotherapy with Oncolytic Adenovirus

Role of brain-derived neurotrophic factor in the protective action of N-methyl-D-aspartate in the apoptotic death of cerebellar granule neurons induced by low potassium

Evaluation of THEO-260 as a novel oncolytic virus therapy for treating stromal rich tumours

Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression

Cavitation-enhanced delivery of macromolecules into an obstructed vessel

Oncolytic adenovirus with hyaluronidase activity that evades neutralizing antibodies: VCN-11

Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01

Inhibition of Delta-Like-4–Mediated Signaling Impairs Reparative Angiogenesis After Ischemia

Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model

Adenovirus Type 5 Interactions with Human Blood Cells May Compromise Systemic Delivery

Use of micro- and nano-sized inertial cavitation nuclei to trigger and map drug release from cavitation-sensitive liposomes

Active Adenoviral Vascular Penetration by Targeted Formation of Heterocellular Endothelial–epithelial Syncytia

Exploitation of cavitation-enhanced heating for release of doxorubicin from thermosensitve liposomes by therapeutic ultrasound

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