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Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Molecules (Basel, Switzerland), 2017-07, Vol.22 (7), p.1192

2017

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Cholinesterase inhibitors as Alzheimer's therapeutics (Review)

Molecular medicine reports, 2019-08, Vol.20 (2), p.1479-1487

Sharma, Kamlesh

2019

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Cholinesterase targeting by polyphenols: A therapeutic approach for the treatment of Alzheimer’s disease

CNS neuroscience & therapeutics, 2018-09, Vol.24 (9), p.753-762

2018

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Natural cholinesterase inhibitors from marine organisms

Natural product reports, 2019-08, Vol.36 (8), p.153-192

2019

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Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease

European journal of medicinal chemistry, 2018-10, Vol.158, p.463-477

2018

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Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase

Biochemical journal, 2013-08, Vol.453 (3), p.393-399

2013

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Rational design, synthesis, and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase

The Journal of biological chemistry, 2020-03, Vol.295 (13), p.4079-4092

2020

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Oximes in organophosphate poisoning: 60 years of hope and despair

Chemico-biological interactions, 2016-11, Vol.259 (Pt B), p.93-98

2016

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A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides

Toxicology and applied pharmacology, 2014-12, Vol.281 (3), p.254-265

2014

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Structure-Based Design and Optimization of Multitarget-Directed 2H‑Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

Journal of medicinal chemistry, 2015-07, Vol.58 (14), p.5561

2015

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Coumarins as cholinesterase inhibitors: A review

Chemico-biological interactions, 2016-07, Vol.254, p.11-23

2016

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The synthesis and cholinesterase inhibitory activities of solasodine analogues with seven-membered F ring

The Journal of steroid biochemistry and molecular biology, 2021-01, Vol.205, p.105776, Article 105776

2021

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Reactivators of butyrylcholinesterase inhibited by organophosphorus compounds

Bioorganic chemistry, 2024-09, Vol.150, p.107526, Article 107526

2024

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New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics

Biomolecules (Basel, Switzerland), 2024-06, Vol.14 (6), p.679

2024

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Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults

Cochrane database of systematic reviews, 2017-08, Vol.8 (9), p.CD012763

2017

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Cholinesterases and the fine line between poison and remedy

Biochemical pharmacology, 2018-07, Vol.153, p.205-216

2018

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Effect of acetylcholinesterase inhibitors on post-stroke cognitive impairment and vascular dementia: A meta-analysis

PloS one, 2020-02, Vol.15 (2), p.e0227820-e0227820

2020

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Metformin – a Future Therapy for Neurodegenerative Diseases: Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla

Pharmaceutical research, 2017-12, Vol.34 (12), p.2614-2627

2017

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Cholinesterases, a target of pharmacology and toxicology

Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia, 2011-09, Vol.155 (3), p.219-223

Pohanka, Miroslav

2011

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Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds

Molecules (Basel, Switzerland), 2018-01, Vol.23 (2), p.250

2018

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Design, synthesis and evaluation of novel tacrine–coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease

European journal of medicinal chemistry, 2013-06, Vol.64, p.540-553

2013

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Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease

European journal of medicinal chemistry, 2016-06, Vol.116, p.200-209

2016

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An update on the utility and safety of cholinesterase inhibitors for the treatment of Alzheimer's disease

Expert opinion on drug safety, 2020-02, Vol.19 (2), p.147-157

2020

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Enzyme ChE, cholinergic therapy and molecular docking: Significant considerations and future perspectives

International journal of immunopathology and pharmacology, 2024-01, Vol.38, p.3946320241289013

Jovičić, Snežana M

2024

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Design, synthesis and anti-Alzheimer’s activity of novel 1,2,3-triazole-chromenone carboxamide derivatives

Bioorganic chemistry, 2019-03, Vol.83, p.391-401

2019

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Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Cholinesterase inhibitors as Alzheimer's therapeutics (Review)

Cholinesterase targeting by polyphenols: A therapeutic approach for the treatment of Alzheimer’s disease

Natural cholinesterase inhibitors from marine organisms

Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease

Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase

Rational design, synthesis, and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase

Oximes in organophosphate poisoning: 60 years of hope and despair

A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides

Structure-Based Design and Optimization of Multitarget-Directed 2H‑Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases

Coumarins as cholinesterase inhibitors: A review

The synthesis and cholinesterase inhibitory activities of solasodine analogues with seven-membered F ring

Reactivators of butyrylcholinesterase inhibited by organophosphorus compounds

New Heterostilbene and Triazole Oximes as Potential CNS-Active and Cholinesterase-Targeted Therapeutics

Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults

Cholinesterases and the fine line between poison and remedy

Effect of acetylcholinesterase inhibitors on post-stroke cognitive impairment and vascular dementia: A meta-analysis

Metformin – a Future Therapy for Neurodegenerative Diseases: Theme: Drug Discovery, Development and Delivery in Alzheimer's Disease Guest Editor: Davide Brambilla

Cholinesterases, a target of pharmacology and toxicology

Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive Compounds

Design, synthesis and evaluation of novel tacrine–coumarin hybrids as multifunctional cholinesterase inhibitors against Alzheimer's disease

Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease

An update on the utility and safety of cholinesterase inhibitors for the treatment of Alzheimer's disease

Enzyme ChE, cholinergic therapy and molecular docking: Significant considerations and future perspectives

Design, synthesis and anti-Alzheimer’s activity of novel 1,2,3-triazole-chromenone carboxamide derivatives

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