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Evaluation of 6-OxP-CD, an Oxime-based cyclodextrin as a viable medical countermeasure against nerve agent poisoning: Experimental and molecular dynamic simulation studies on its inclusion complexes with cyclosarin, soman and VX

PloS one, 2023-03, Vol.18 (3), p.e0283181-e0283181

2023

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Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data

The journal of physical chemistry. B, 2017-05, Vol.121 (20), p.5228-5237

2017

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Maternal exposure to an environmentally relevant dose of triclocarban results in perinatal exposure and potential alterations in offspring development in the mouse model

PloS one, 2017-08, Vol.12 (8), p.e0181996-e0181996

2017

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Countermeasures for Preventing and Treating Opioid Overdose

Clinical pharmacology and therapeutics, 2021-03, Vol.109 (3), p.578-590

2021

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Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

Science translational medicine, 2015-07, Vol.7 (298), p.298ra117

2015

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Development of a CNS-permeable reactivator for nerve agent exposure: an iterative, multi-disciplinary approach

Scientific reports, 2021-07, Vol.11 (1), p.15567-16, Article 15567

2021

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Manipulation of the Gut Microbiome Alters Acetaminophen Biodisposition in Mice

Scientific reports, 2020-03, Vol.10 (1), p.4571, Article 4571

2020

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Comparative Pharmacokinetics of High and Low Doses of the Herbicide Propanil in Mice

Chemical research in toxicology, 2018-10, Vol.31 (10), p.1080-1085

2018

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Use of Accelerator Mass Spectrometry in Human Health and Molecular Toxicology

Chemical research in toxicology, 2016-12, Vol.29 (12), p.1976-1986

2016

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Determining the Pharmacokinetics and Long-Term Biodistribution of SiO2 Nanoparticles In Vivo Using Accelerator Mass Spectrometry

Nano letters, 2012-11, Vol.12 (11), p.5532-5538

2012

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Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel

Chemical research in toxicology, 2018-12, Vol.31 (12), p.1293-1304

2018

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Toward Predicting Acute Myeloid Leukemia Patient Response to 7 + 3 Induction Chemotherapy via Diagnostic Microdosing

Chemical research in toxicology, 2018-10, Vol.31 (10), p.1042-1051

2018

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The biodistribution and pharmacokinetics of the oxime acetylcholinesterase reactivator RS194B in guinea pigs

Chemico-biological interactions, 2017-11, Vol.277 (C), p.159-167

2017

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Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2‑Amino-1-methyl-6-phenylimidazo[4,5‑b]pyridine and Albumin in Humans

Chemical research in toxicology, 2017-02, Vol.30 (2), p.705-714

2017

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Tracking Tumor Colonization in Xenograft Mouse Models Using Accelerator Mass Spectrometry

Scientific reports, 2018-10, Vol.8 (1), p.15013-10, Article 15013

2018

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P165 - Improved on-line accelerator mass spectrometry techniques for the analysis of environmental chemicals at ultra-low exposure levels

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S73-S73

2020

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Mutagenic potency of food-derived heterocyclic amines

Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 2007-03, Vol.616 (1), p.90-94

2007

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Disposition of the Dietary Mutagen 2‑Amino-3,8-dimethylimidazo[4,5‑f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans

Chemical research in toxicology, 2016-03, Vol.29 (3), p.352-358

2016

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Use of microdosing and accelerator mass spectrometry to evaluate the pharmacokinetic linearity of a novel tricyclic GyrB/ParE inhibitor in rats

Antimicrobial agents and chemotherapy, 2014-11, Vol.58 (11), p.6477-6483

2014

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Diagnostic Microdosing Approach to Study Gemcitabine Resistance

Chemical research in toxicology, 2016-11, Vol.29 (11), p.1843-1848

2016

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Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

PloS one, 2016-01, Vol.11 (1), p.e0146256

2016

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The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10541-10547

2006

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N-Glucuronidation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) and N-hydroxy-PhIP by specific human UDP-glucuronosyltransferases

Carcinogenesis (New York), 2001-07, Vol.22 (7), p.1087-1093

2001

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Human UDP-Glucuronosyltransferase 1A1 Is the Primary Enzyme Responsible for the N-Glucuronidation of N-Hydroxy-PhIP in Vitro

Chemical research in toxicology, 2004-08, Vol.17 (8), p.1137-1144

2004

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Radiocarbon Tracers in Toxicology and Medicine: Recent Advances in Technology and Science

Toxics (Basel), 2019-05, Vol.7 (2), p.27

2019

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Evaluation of 6-OxP-CD, an Oxime-based cyclodextrin as a viable medical countermeasure against nerve agent poisoning: Experimental and molecular dynamic simulation studies on its inclusion complexes with cyclosarin, soman and VX

Predicting a Drug’s Membrane Permeability: A Computational Model Validated With in Vitro Permeability Assay Data

Maternal exposure to an environmentally relevant dose of triclocarban results in perinatal exposure and potential alterations in offspring development in the mouse model

Countermeasures for Preventing and Treating Opioid Overdose

Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

Development of a CNS-permeable reactivator for nerve agent exposure: an iterative, multi-disciplinary approach

Manipulation of the Gut Microbiome Alters Acetaminophen Biodisposition in Mice

Comparative Pharmacokinetics of High and Low Doses of the Herbicide Propanil in Mice

Use of Accelerator Mass Spectrometry in Human Health and Molecular Toxicology

Determining the Pharmacokinetics and Long-Term Biodistribution of SiO2 Nanoparticles In Vivo Using Accelerator Mass Spectrometry

Correlation of Platinum Cytotoxicity to Drug-DNA Adduct Levels in a Breast Cancer Cell Line Panel

Toward Predicting Acute Myeloid Leukemia Patient Response to 7 + 3 Induction Chemotherapy via Diagnostic Microdosing

The biodistribution and pharmacokinetics of the oxime acetylcholinesterase reactivator RS194B in guinea pigs

Mass Spectrometric Characterization of an Acid-Labile Adduct Formed with 2‑Amino-1-methyl-6-phenylimidazo[4,5‑b]pyridine and Albumin in Humans

Tracking Tumor Colonization in Xenograft Mouse Models Using Accelerator Mass Spectrometry

P165 - Improved on-line accelerator mass spectrometry techniques for the analysis of environmental chemicals at ultra-low exposure levels

Mutagenic potency of food-derived heterocyclic amines

Disposition of the Dietary Mutagen 2‑Amino-3,8-dimethylimidazo[4,5‑f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans

Use of microdosing and accelerator mass spectrometry to evaluate the pharmacokinetic linearity of a novel tricyclic GyrB/ParE inhibitor in rats

Diagnostic Microdosing Approach to Study Gemcitabine Resistance

Molecular Dissection of Induced Platinum Resistance through Functional and Gene Expression Analysis in a Cell Culture Model of Bladder Cancer

The urinary metabolite profile of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine is predictive of colon dna adducts after a low-dose exposure in humans

N-Glucuronidation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine (PhIP) and N-hydroxy-PhIP by specific human UDP-glucuronosyltransferases

Human UDP-Glucuronosyltransferase 1A1 Is the Primary Enzyme Responsible for the N-Glucuronidation of N-Hydroxy-PhIP in Vitro

Radiocarbon Tracers in Toxicology and Medicine: Recent Advances in Technology and Science

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