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Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

The Journal of neuroscience, 2015-08, Vol.35 (33), p.11500-11513

2015

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Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Journal of Alzheimer's disease, 2017-01, Vol.55 (2), p.849-864

2017

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Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

CNS neuroscience & therapeutics, 2016-07, Vol.22 (7), p.611-616

2016

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The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

Atherosclerosis, 2012-01, Vol.220 (1), p.102-109

2012

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The Insulin/IGF System in Mammalian Sexual Development and Reproduction

International journal of molecular sciences, 2019-09, Vol.20 (18), p.4440

2019

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Liver-Specific GH Receptor Gene-Disrupted (LiGHRKO) Mice Have Decreased Endocrine IGF-I, Increased Local IGF-I, and Altered Body Size, Body Composition, and Adipokine Profiles

Endocrinology (Philadelphia), 2014-05, Vol.155 (5), p.1793-1805

2014

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Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma

Gut, 2017-03, Vol.66 (3), p.530-540

2017

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IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Aging cell, 2015-12, Vol.14 (6), p.1034-1044

2015

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Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells

American journal of physiology: endocrinology and metabolism, 2006-11, Vol.291 (5), p.E1124-E1130

2006

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Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Diabetes (New York, N.Y.), 2017-01, Vol.66 (1), p.64-74

2017

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Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis

Cardiovascular diabetology, 2016-12, Vol.15 (1), p.161-161, Article 161

2016

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Localization of Insulin-Like Growth Factor-I (IGF-I) and IGF-I Receptor (IGF-IR) in Equine Testes

Reproduction in domestic animals, 2011-04, Vol.46 (2), p.221-228

2011

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Systemic Organ Wasting Induced by Localized Expression of the Secreted Insulin/IGF Antagonist ImpL2

Developmental cell, 2015-04, Vol.33 (1), p.36-46

2015

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Exogenous GLP-2 and IGF-I induce a differential intestinal response in IGF binding protein-3 and -5 double knockout mice

American journal of physiology: Gastrointestinal and liver physiology, 2012-04, Vol.302 (8), p.G794-G804

2012

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IGF‐I regulates the age‐dependent signaling peptide humanin

Aging cell, 2014-10, Vol.13 (5), p.958-961

2014

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Aging Impairs IGF‐I Receptor Activation and Induces Skeletal Resistance to IGF‐I

Journal of bone and mineral research, 2007-08, Vol.22 (8), p.1271-1279

2007

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Insulin‐like growth factor‐1 (IGF‐1) enhances the osteogenic activity of bone morphogenetic protein‐6 (BMP‐6) in vitro and in vivo, and together have a stronger osteogenic effect than when IGF‐1 is combined with BMP‐2

Journal of biomedical materials research. Part A, 2017-07, Vol.105 (7), p.1867-1875

2017

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Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity

Nature communications, 2015-04, Vol.6 (1), p.6780-6780, Article 6780

2015

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IGF-I stimulates neurogenesis in the hypothalamus of adult rats

The European journal of neuroscience, 2010-05, Vol.31 (9), p.1533-1548

2010

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A critical role for IGF-II in memory consolidation and enhancement

Nature (London), 2011-01, Vol.469 (7331), p.491-497

2011

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FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma

Clinical cancer research, 2017-10, Vol.23 (20), p.6227-6238

2017

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Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1

The journals of gerontology. Series A, Biological sciences and medical sciences, 2012-06, Vol.67 (6), p.611-625

2012

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TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

Nature communications, 2015-08, Vol.6 (1), p.7951-7951, Article 7951

2015

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IGF‐1 regulates astrocytic phagocytosis and inflammation through the p110α isoform of PI3K in a sex‐specific manner

Glia, 2022-06, Vol.70 (6), p.1153-1169

2022

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IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner

Scientific reports, 2016-10, Vol.6 (1), p.34605-34605, Article 34605

2016

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Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

The Insulin/IGF System in Mammalian Sexual Development and Reproduction

Liver-Specific GH Receptor Gene-Disrupted (LiGHRKO) Mice Have Decreased Endocrine IGF-I, Increased Local IGF-I, and Altered Body Size, Body Composition, and Adipokine Profiles

Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma

IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells

Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis

Localization of Insulin-Like Growth Factor-I (IGF-I) and IGF-I Receptor (IGF-IR) in Equine Testes

Systemic Organ Wasting Induced by Localized Expression of the Secreted Insulin/IGF Antagonist ImpL2

Exogenous GLP-2 and IGF-I induce a differential intestinal response in IGF binding protein-3 and -5 double knockout mice

IGF‐I regulates the age‐dependent signaling peptide humanin

Aging Impairs IGF‐I Receptor Activation and Induces Skeletal Resistance to IGF‐I

Insulin‐like growth factor‐1 (IGF‐1) enhances the osteogenic activity of bone morphogenetic protein‐6 (BMP‐6) in vitro and in vivo, and together have a stronger osteogenic effect than when IGF‐1 is combined with BMP‐2

Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity

IGF-I stimulates neurogenesis in the hypothalamus of adult rats

A critical role for IGF-II in memory consolidation and enhancement

FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid Liposarcoma

Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1

TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

IGF‐1 regulates astrocytic phagocytosis and inflammation through the p110α isoform of PI3K in a sex‐specific manner

IGF-I induces senescence of hepatic stellate cells and limits fibrosis in a p53-dependent manner

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