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Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Cell reports (Cambridge), 2021-08, Vol.36 (7), p.109542-109542, Article 109542

2021

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Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Oncotarget, 2015-06, Vol.6 (18), p.16084-16105

2015

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Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

The EMBO journal, 2023-10, Vol.42 (19), p.e113328-e113328

2023

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Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Cellular and molecular life sciences : CMLS, 2016-01, Vol.73 (2), p.271-290

2016

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Therapeutic Targeting of the IGF Axis

Cells (Basel, Switzerland), 2019-08, Vol.8 (8), p.895

2019

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lncRNA NR2F1‐AS1 promotes breast cancer angiogenesis through activating IGF‐1/IGF‐1R/ERK pathway

Journal of cellular and molecular medicine, 2020-07, Vol.24 (14), p.8236-8247

2020

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Effects of GH/IGF axis on bone and cartilage

Molecular and cellular endocrinology, 2021-01, Vol.519, p.111052-111052, Article 111052

2021

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Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling

The Journal of biological chemistry, 2010-03, Vol.285 (12), p.8743-8758

2010

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In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Cancer cell, 2004-03, Vol.5 (3), p.231-239

2004

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Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The FASEB journal, 2014-03, Vol.28 (3), p.1294-1305

2014

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IGF‐I protects porcine granulosa cells from hypoxia‐induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

The FASEB journal, 2024-01, Vol.38 (1), p.e23332-n/a

2024

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Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Aging cell, 2015-10, Vol.14 (5), p.847-856

2015

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Effects of IGF‐1 isoforms on muscle growth and sarcopenia

Aging cell, 2019-06, Vol.18 (3), p.e12954-n/a

2019

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The decline and fall of the IGF-I receptor

Journal of cellular physiology, 2013-04, Vol.228 (4), p.675-679

Baserga, Renato

2013

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The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Nature medicine, 2012-11, Vol.18 (11), p.1643-1650

2012

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IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Aging cell, 2015-12, Vol.14 (6), p.1034-1044

2015

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Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells

American journal of physiology: endocrinology and metabolism, 2006-11, Vol.291 (5), p.E1124-E1130

2006

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Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

FEBS letters, 2002-07, Vol.522 (1), p.156-160

2002

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Humanin: Functional Interfaces with IGF-I

Growth hormone & IGF research, 2016-08, Vol.29, p.21-27

2016

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IGF-II is regulated by microRNA-125b in skeletal myogenesis

The Journal of cell biology, 2011-01, Vol.192 (1), p.69-81

2011

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Systemic Organ Wasting Induced by Localized Expression of the Secreted Insulin/IGF Antagonist ImpL2

Developmental cell, 2015-04, Vol.33 (1), p.36-46

2015

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IGF-II Promotes Stemness of Neural Restricted Precursors

Stem cells (Dayton, Ohio), 2012-06, Vol.30 (6), p.1265-1276

2012

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IGF‐I regulates the age‐dependent signaling peptide humanin

Aging cell, 2014-10, Vol.13 (5), p.958-961

2014

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Molecular interactions of the IGF system

Cytokine & growth factor reviews, 2005-08, Vol.16 (4), p.421-439

2005

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Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling

Developmental cell, 2018-10, Vol.47 (1), p.67-79.e5

2018

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Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Therapeutic Targeting of the IGF Axis

lncRNA NR2F1‐AS1 promotes breast cancer angiogenesis through activating IGF‐1/IGF‐1R/ERK pathway

Effects of GH/IGF axis on bone and cartilage

In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

IGF‐I protects porcine granulosa cells from hypoxia‐induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Effects of IGF‐1 isoforms on muscle growth and sarcopenia

The decline and fall of the IGF-I receptor

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Insulin and IGF-I action on insulin receptors, IGF-I receptors, and hybrid insulin/IGF-I receptors in vascular smooth muscle cells

Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

Humanin: Functional Interfaces with IGF-I

IGF-II is regulated by microRNA-125b in skeletal myogenesis

Systemic Organ Wasting Induced by Localized Expression of the Secreted Insulin/IGF Antagonist ImpL2

IGF-II Promotes Stemness of Neural Restricted Precursors

IGF‐I regulates the age‐dependent signaling peptide humanin

Molecular interactions of the IGF system

Drug Synergy Slows Aging and Improves Healthspan through IGF and SREBP Lipid Signaling

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