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Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Cell reports (Cambridge), 2021-08, Vol.36 (7), p.109542-109542, Article 109542

2021

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Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Oncotarget, 2015-06, Vol.6 (18), p.16084-16105

2015

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Therapeutic Targeting of the IGF Axis

Cells (Basel, Switzerland), 2019-08, Vol.8 (8), p.895

2019

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In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Cancer cell, 2004-03, Vol.5 (3), p.231-239

2004

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Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Aging cell, 2015-10, Vol.14 (5), p.847-856

2015

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Effects of IGF‐1 isoforms on muscle growth and sarcopenia

Aging cell, 2019-06, Vol.18 (3), p.e12954-n/a

2019

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The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Nature medicine, 2012-11, Vol.18 (11), p.1643-1650

2012

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IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

Aging cell, 2015-12, Vol.14 (6), p.1034-1044

2015

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IGF-II is regulated by microRNA-125b in skeletal myogenesis

The Journal of cell biology, 2011-01, Vol.192 (1), p.69-81

2011

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Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

FEBS letters, 2002-07, Vol.522 (1), p.156-160

2002

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IGF‐I regulates the age‐dependent signaling peptide humanin

Aging cell, 2014-10, Vol.13 (5), p.958-961

2014

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IGF-II Promotes Stemness of Neural Restricted Precursors

Stem cells (Dayton, Ohio), 2012-06, Vol.30 (6), p.1265-1276

2012

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Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer

Oncotarget, 2017-05, Vol.8 (18), p.29668-29678

2017

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The calcium channel TRPV6 is a novel regulator of RANKL‐induced osteoclastic differentiation and bone absorption activity through the IGF–PI3K–AKT pathway

Cell proliferation, 2021-01, Vol.54 (1), p.e12955-n/a

2021

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Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II

PloS one, 2011-11, Vol.6 (11), p.e27488

2011

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How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

Structure (London), 2020-07, Vol.28 (7), p.786-798.e6

2020

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Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake

Aging cell, 2015-08, Vol.14 (4), p.511-523

2015

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Oral submucous fibrosis stimulates invasion and epithelial‐mesenchymal transition in oral squamous cell carcinoma by activating MMP‐2 and IGF‐IR

Journal of cellular and molecular medicine, 2021-10, Vol.25 (20), p.9814-9825

2021

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Impaired myoblast differentiation and muscle IGF‐1 receptor signaling pathway activation after N‐glycosylation inhibition

The FASEB journal, 2024-07, Vol.38 (13), p.e23797-n/a

2024

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Deletion of muscle IGF‐I transiently impairs growth and progressively disrupts glucose homeostasis in male mice

The FASEB journal, 2019-01, Vol.33 (1), p.181-194

2019

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Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt

American Journal of Physiology: Cell Physiology, 2009-11, Vol.297 (5), p.1124-1132

2009

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IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loop

The Journal of cell biology, 2008-09, Vol.182 (5), p.979-991

2008

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Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions

The EMBO journal, 1998-11, Vol.17 (22), p.6558-6572

1998

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Actions and interactions of IGF-I and MMPs during muscle regeneration

Seminars in cell & developmental biology, 2021-11, Vol.119, p.11-22

2021

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IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells

Science signaling, 2022-08, Vol.15 (747), p.eabj5879

2022

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Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Therapeutic Targeting of the IGF Axis

In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Effects of IGF‐1 isoforms on muscle growth and sarcopenia

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging

IGF-II is regulated by microRNA-125b in skeletal myogenesis

Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

IGF‐I regulates the age‐dependent signaling peptide humanin

IGF-II Promotes Stemness of Neural Restricted Precursors

Novel role of cannabinoid receptor 2 in inhibiting EGF/EGFR and IGF-I/IGF-IR pathways in breast cancer

The calcium channel TRPV6 is a novel regulator of RANKL‐induced osteoclastic differentiation and bone absorption activity through the IGF–PI3K–AKT pathway

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II

How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake

Oral submucous fibrosis stimulates invasion and epithelial‐mesenchymal transition in oral squamous cell carcinoma by activating MMP‐2 and IGF‐IR

Impaired myoblast differentiation and muscle IGF‐1 receptor signaling pathway activation after N‐glycosylation inhibition

Deletion of muscle IGF‐I transiently impairs growth and progressively disrupts glucose homeostasis in male mice

Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt

IGFBP-5 regulates muscle cell differentiation by binding to IGF-II and switching on the IGF-II auto-regulation loop

Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions

Actions and interactions of IGF-I and MMPs during muscle regeneration

IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells

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