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Fatty Acids and Insulin Secretion: From FFAR and Near?

Diabetes (New York, N.Y.), 2018-10, Vol.67 (10), p.1932-1934

Poitout, Vincent

2018

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Targeting lipid GPCRs to treat type 2 diabetes mellitus - progress and challenges

Nature reviews. Endocrinology, 2021-03, Vol.17 (3), p.162-175

2021

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The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

Trends in endocrinology and metabolism, 2013-08, Vol.24 (8), p.398-407

2013

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Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans

Scientific reports, 2021-05, Vol.11 (1), p.11283-11283, Article 11283

2021

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Glucolipotoxicity of the pancreatic beta cell

Biochimica et biophysica acta, 2010-03, Vol.1801 (3), p.289-298

2010

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The Role and Future of FFA1 as a Therapeutic Target

Free Fatty Acid Receptors, 2017-01, Vol.236, p.159-180

2017

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Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling

PloS one, 2012-04, Vol.7 (4), p.e36200

2012

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β-Cell Glucose Toxicity, Lipotoxicity, and Chronic Oxidative Stress in Type 2 Diabetes

Diabetes (New York, N.Y.), 2004-02, Vol.53 (suppl 1), p.S119-S124

2004

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Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Diabetes (New York, N.Y.), 2010-02, Vol.59 (2), p.440-447

2010

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Considerations and guidelines for mouse metabolic phenotyping in diabetes research

Diabetologia, 2018-03, Vol.61 (3), p.526-538

2018

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Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats

Diabetologia, 2017-05, Vol.60 (5), p.879-888

2017

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Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

Diabetes (New York, N.Y.), 2009-11, Vol.58 (11), p.2607-2615

2009

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Modulating GPR40: therapeutic promise and potential in diabetes

Drug discovery today, 2013-12, Vol.18 (23-24), p.1301-1308

2013

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Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice

The international journal of neuropsychopharmacology, 2016-07, Vol.19 (7), p.pyw014

2016

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The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding

Diabetes (New York, N.Y.), 2008-09, Vol.57 (9), p.2432-2437

2008

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A Call for Improved Reporting of Human Islet Characteristics in Research Articles

Diabetes (New York, N.Y.), 2019-02, Vol.68 (2), p.239-240

2019

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The Free Fatty Acid Receptor G Protein-coupled Receptor 40 (GPR40) Protects from Bone Loss through Inhibition of Osteoclast Differentiation

The Journal of biological chemistry, 2013-03, Vol.288 (9), p.6542-6551

2013

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Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells

Cell reports (Cambridge), 2023-05, Vol.42 (5), p.112500-112500, Article 112500

2023

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GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo

Diabetes (New York, N.Y.), 2007-04, Vol.56 (4), p.1087-1094

2007

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Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Molecular metabolism (Germany), 2021-03, Vol.45, p.101166-101166, Article 101166

2021

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Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (7), p.2376-2381

2012

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Palmitate Inhibits Insulin Gene Expression by Altering PDX-1 Nuclear Localization and Reducing MafA Expression in Isolated Rat Islets of Langerhans

The Journal of biological chemistry, 2005-09, Vol.280 (37), p.32413-32418

2005

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Editorial: Pancreas Imaging Across the Spectrum

Frontiers in endocrinology (Lausanne), 2021-01, Vol.12, p.832519-832519

2021

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Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice

Molecular metabolism (Germany), 2014-12, Vol.3 (9), p.848-854

2014

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β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood

JCI insight, 2022-11, Vol.7 (21)

2022

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Fatty Acids and Insulin Secretion: From FFAR and Near?

Targeting lipid GPCRs to treat type 2 diabetes mellitus - progress and challenges

The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?

Pronounced proliferation of non-beta cells in response to beta-cell mitogens in isolated human islets of Langerhans

Glucolipotoxicity of the pancreatic beta cell

The Role and Future of FFA1 as a Therapeutic Target

Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling

β-Cell Glucose Toxicity, Lipotoxicity, and Chronic Oxidative Stress in Type 2 Diabetes

Lack of TXNIP Protects Against Mitochondria-Mediated Apoptosis but Not Against Fatty Acid–Induced ER Stress–Mediated β-Cell Death

Considerations and guidelines for mouse metabolic phenotyping in diabetes research

Glucose and fatty acids synergistically and reversibly promote beta cell proliferation in rats

Deletion of GPR40 Impairs Glucose-Induced Insulin Secretion In Vivo in Mice Without Affecting Intracellular Fuel Metabolism in Islets

Modulating GPR40: therapeutic promise and potential in diabetes

Central Agonism of GPR120 Acutely Inhibits Food Intake and Food Reward and Chronically Suppresses Anxiety-Like Behavior in Mice

The Fatty Acid Receptor GPR40 Plays a Role in Insulin Secretion In Vivo After High-Fat Feeding

A Call for Improved Reporting of Human Islet Characteristics in Research Articles

The Free Fatty Acid Receptor G Protein-coupled Receptor 40 (GPR40) Protects from Bone Loss through Inhibition of Osteoclast Differentiation

Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells

GPR40 Is Necessary but Not Sufficient for Fatty Acid Stimulation of Insulin Secretion In Vivo

Free fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice

Glucose activates free fatty acid receptor 1 gene transcription via phosphatidylinositol-3-kinase-dependent O-GlcNAcylation of pancreas-duodenum homeobox-1

Palmitate Inhibits Insulin Gene Expression by Altering PDX-1 Nuclear Localization and Reducing MafA Expression in Isolated Rat Islets of Langerhans

Editorial: Pancreas Imaging Across the Spectrum

Defective insulin secretory response to intravenous glucose in C57Bl/6J compared to C57Bl/6N mice

β Cell mass expansion during puberty involves serotonin signaling and determines glucose homeostasis in adulthood

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