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Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies

Immunity (Cambridge, Mass.), 2012-09, Vol.37 (3), p.412-425

2012

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Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

Cell, 2013-03, Vol.153 (1), p.126-138

2013

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Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7

Nature (London), 2021-05, Vol.593 (7857), p.130-135

2021

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Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

Journal of Virology, 2011-08, Vol.85 (15), p.7788-7796

2011

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Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies

Cell, 2014-07, Vol.158 (3), p.481-491

2014

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Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants

Nature (London), 2021-07, Vol.595 (7866), p.278-282

2021

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Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

Nature (London), 2012-11, Vol.491 (7424), p.406-412

2012

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

Science (American Association for the Advancement of Science), 2010-08, Vol.329 (5993), p.811-817

2010

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Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield

Structure (London), 2017-10, Vol.25 (10), p.1631-1639.e2

2017

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Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

Cell, 2016-07, Vol.166 (3), p.609-623

2016

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Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Science (American Association for the Advancement of Science), 2011-09, Vol.333 (6049), p.1593-1602

2011

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Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

Journal of Virology, 2010-08, Vol.84 (16), p.8098-8110

2010

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Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

PloS one, 2016-06, Vol.11 (6), p.e0157409

2016

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Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16

Nature structural & molecular biology, 2013-07, Vol.20 (7), p.804-813

2013

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Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (15), p.5663-5668

2012

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Structural basis of malaria RIFIN binding by LILRB1-containing antibodies

Nature (London), 2021-04, Vol.592 (7855), p.639-643

2021

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Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262

Proteins, structure, function, and bioinformatics, 2015-03, Vol.83 (3), p.590-596

2015

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Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold

Science (American Association for the Advancement of Science), 2011-10, Vol.334 (6054), p.373-376

2011

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Structural basis of respiratory syncytial virus neutralization by motavizumab

Nature structural & molecular biology, 2010-02, Vol.17 (2), p.248-250

2010

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Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

Nature structural & molecular biology, 2016-09, Vol.23 (9), p.811-820

2016

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Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (3), p.1166-1171

2010

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Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

Journal of virology, 2015-08, Vol.89 (16), p.8334-8345

2015

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Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

Molecular cell, 2010-03, Vol.37 (5), p.656-667

2010

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Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies

Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Broad and potent neutralization of HIV-1 by a gp41-specific human antibody

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

Structural basis for diverse N-glycan recognition by HIV-1-neutralizing V1-V2-directed antibody PG16

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

Structural basis of malaria RIFIN binding by LILRB1-containing antibodies

Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262

Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold

Structural basis of respiratory syncytial virus neutralization by motavizumab

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

Broadly Neutralizing Human Immunodeficiency Virus Type 1 Antibody Gene Transfer Protects Nonhuman Primates from Mucosal Simian-Human Immunodeficiency Virus Infection

Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

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