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Aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase

Nature communications, 2022-01, Vol.13 (1), p.62-62, Article 62

2022

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Frontispiece: Perfluoroaryl and Perfluoroheteroaryl Reagents as Emerging New Tools for Peptide Synthesis, Modification and Bioconjugation

Chemistry : a European journal, 2022-02, Vol.28 (7), p.n/a

2022

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Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditionsElectronic supplementary information (ESI) available. CCDC 1856218-1856219. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8ob02899k

2019-02

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Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions† †Electronic supplementary information (ESI) available. CCDC 1856218–1856219. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8ob02899k

Organic & biomolecular chemistry, 2019-01, Vol.17 (8), p.2110-2115

2019

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HFO‐1234yf as a CF 3 Building Block: Synthesis of Trifluoromethyl Quinoline and Chromene Derivatives from Trifluoromethyl‐ynones

European journal of organic chemistry, 2023-03, Vol.26 (11)

2023

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Kinetic resolution of alkyne-substituted quaternary oxindoles via copper catalysed azide-alkyne cycloadditionsElectronic supplementary information (ESI) available: Experimental procedures, HPLC traces, NMR data and detailed screening tables. See DOI: 10.1039/c5cc04886a

2015-11

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The Bull-James assembly as a chiral auxiliary and shift reagent in kinetic resolution of alkyne amines by the CuAAC reactionDedicated to the 60th Birthday of Tony Czarnik.1Electronic supplementary information (ESI) available. CCDC 1477891. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c6ob01623e

2016-11

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ChemInform Abstract: Asymmetric Copper‐Catalyzed Azide‐Alkyne Cycloadditions

ChemInform, 2016-07, Vol.47 (30), p.no-no

2016

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ChemInform Abstract: Kinetic Resolution of Alkyne‐Substituted Quaternary Oxindoles via Copper Catalyzed Azide—Alkyne Cycloadditions

ChemInform, 2016-03, Vol.47 (13), p.no-no

2016

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ChemInform Abstract: Recent Advances in the Use of Chiral Metal Complexes with Achiral Ligands for Application in Asymmetric Catalysis

ChemInform, 2015-09, Vol.46 (37), p.no-no

2015

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Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma

The New England journal of medicine, 2018-01, Vol.378 (1), p.35-47

2018

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Intensive Blood-Pressure Control in Hypertensive Chronic Kidney Disease

The New England journal of medicine, 2010-09, Vol.363 (10), p.918-929

2010

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NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review

Journal of the American College of Cardiology, 2021-04, Vol.77 (16), p.2040-2052

2021

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Normal and pathogenic variation of RFC1 repeat expansions: implications for clinical diagnosis

Brain (London, England : 1878), 2023-12, Vol.146 (12), p.5060-5069

2023

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Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy

Genetics in medicine, 2021-02, Vol.23 (2), p.408-414

2021

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Substitution mutational signatures in whole-genome-sequenced cancers in the UK population

Science (American Association for the Advancement of Science), 2022-04, Vol.376 (6591)

2022

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Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features

Nature genetics, 2022-11, Vol.54 (11), p.1675

2022

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The NHS England 100,000 Genomes Project: feasibility and utility of centralised genome sequencing for children with cancer

British journal of cancer, 2022-07, Vol.127 (1), p.137-144

2022

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Specialist multidisciplinary input maximises rare disease diagnoses from whole genome sequencing

Nature communications, 2022-11, Vol.13 (1), p.6324-6324, Article 6324

2022

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Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome

Scientific reports, 2022-02, Vol.12 (1), p.2722-13, Article 2722

2022

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Assessing the digenic model in rare disorders using population sequencing data

European journal of human genetics : EJHG, 2022-12, Vol.30 (12), p.1439-1443

2022

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Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders

Nature communications, 2023-07, Vol.14 (1), p.4109-4109, Article 4109

2023

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Targeting de novo loss-of-function variants in constrained disease genes improves diagnostic rates in the 100,000 Genomes Project

Human genetics, 2023-03, Vol.142 (3), p.351-362

2023

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Aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase

Frontispiece: Perfluoroaryl and Perfluoroheteroaryl Reagents as Emerging New Tools for Peptide Synthesis, Modification and Bioconjugation

Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditionsElectronic supplementary information (ESI) available. CCDC 1856218-1856219. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8ob02899k

Tetrafluoropyridyl (TFP): a general phenol protecting group readily cleaved under mild conditions† †Electronic supplementary information (ESI) available. CCDC 1856218–1856219. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c8ob02899k

HFO‐1234yf as a CF 3 Building Block: Synthesis of Trifluoromethyl Quinoline and Chromene Derivatives from Trifluoromethyl‐ynones

Kinetic resolution of alkyne-substituted quaternary oxindoles via copper catalysed azide-alkyne cycloadditionsElectronic supplementary information (ESI) available: Experimental procedures, HPLC traces, NMR data and detailed screening tables. See DOI: 10.1039/c5cc04886a

ChemInform Abstract: Asymmetric Copper‐Catalyzed Azide‐Alkyne Cycloadditions

ChemInform Abstract: Kinetic Resolution of Alkyne‐Substituted Quaternary Oxindoles via Copper Catalyzed Azide—Alkyne Cycloadditions

ChemInform Abstract: Recent Advances in the Use of Chiral Metal Complexes with Achiral Ligands for Application in Asymmetric Catalysis

Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma

Intensive Blood-Pressure Control in Hypertensive Chronic Kidney Disease

NHLBI-CMREF Workshop Report on Pulmonary Vascular Disease Classification: JACC State-of-the-Art Review

Normal and pathogenic variation of RFC1 repeat expansions: implications for clinical diagnosis

DYNC2H1 hypomorphic or retina-predominant variants cause nonsyndromic retinal degeneration

Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy

Substitution mutational signatures in whole-genome-sequenced cancers in the UK population

Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features

The NHS England 100,000 Genomes Project: feasibility and utility of centralised genome sequencing for children with cancer

Specialist multidisciplinary input maximises rare disease diagnoses from whole genome sequencing

Genotype-phenotype correlations for COL4A3-COL4A5 variants resulting in Gly substitutions in Alport syndrome

Assessing the digenic model in rare disorders using population sequencing data

Diverse ancestry whole-genome sequencing association study identifies TBX5 and PTK7 as susceptibility genes for posterior urethral valves

Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders

Targeting de novo loss-of-function variants in constrained disease genes improves diagnostic rates in the 100,000 Genomes Project

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