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Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

Science (American Association for the Advancement of Science), 2012-09, Vol.337 (6099), p.1231-1235

2012

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FGF-dependent metabolic control of vascular development

Nature (London), 2017-05, Vol.545 (7653), p.224-228

2017

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In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia

PloS one, 2020-12, Vol.15 (12), p.e0244368-e0244368

2020

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Ensemble-Based Replica Exchange Alchemical Free Energy Methods: The Effect of Protein Mutations on Inhibitor Binding

Journal of chemical theory and computation, 2019-02, Vol.15 (2), p.1265-1277

2019

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A Tetravalent Bispecific Antibody Selectively Inhibits Diverse FGFR3 Oncogenic Variants

Cancer research (Chicago, Ill.), 2024-07, Vol.84 (13), p.2169-2180

2024

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Characterization of membrane protein interactions in plasma membrane derived vesicles with quantitative imaging Förster resonance energy transfer

Accounts of chemical research, 2015-08, Vol.48 (8), p.2262-2269

2015

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Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation

Osteoarthritis and cartilage, 2015-03, Vol.23 (3), p.443-453

2015

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Effect of Thanatophoric Dysplasia Type I Mutations on FGFR3 Dimerization

Biophysical journal, 2015-01, Vol.108 (2), p.272-278

2015

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Antitumor Activity of Tasurgratinib as an Orally Available FGFR1-3 Inhibitor in Cholangiocarcinoma Models With FGFR2-fusion

Anticancer research, 2024-06, Vol.44 (6), p.2393-2406

2024

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Kinase Activity of Fibroblast Growth Factor Receptor 3 Regulates Activity of the Papillomavirus E2 Protein

Journal of virology, 2017-10, Vol.91 (20)

2017

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Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma

Cancer research (Chicago, Ill.), 2013-02, Vol.73 (4), p.1298-1307

2013

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Biomarker-Oriented Therapy in Bladder and Renal Cancer

International journal of molecular sciences, 2021-03, Vol.22 (6), p.2832

2021

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Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer

European urology, 2017-06, Vol.71 (6), p.961-969

2017

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A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model

Human molecular genetics, 2012-02, Vol.21 (4), p.841-851

2012

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Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia

Journal of medicinal chemistry, 2024-09, Vol.67 (18), p.16737-16756

2024

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Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer

The Journal of pathology, 2007-09, Vol.213 (1), p.82-90

2007

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Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (22), p.4986-4997

2020

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Exploring mechanisms of FGF signalling through the lens of structural biology

Nature reviews. Molecular cell biology, 2013-03, Vol.14 (3), p.166-180

2013

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Genetically confirmed thanatophoric dysplasia with fibroblast growth factor receptor 3 mutation

Experimental and molecular pathology, 2017-04, Vol.102 (2), p.290-295

2017

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Pemigatinib: First Approval

Drugs (New York, N.Y.), 2020-06, Vol.80 (9), p.923-929

Hoy, Sheridan M.

2020

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Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells

Oncogene, 2015-04, Vol.34 (17), p.2167-2177

2015

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Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance

Cancer research (Chicago, Ill.), 2015-03, Vol.75 (5), p.880-891

2015

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The Transition from Radial Glial to Intermediate Progenitor Cell Is Inhibited by FGF Signaling during Corticogenesis

The Journal of neuroscience, 2009-11, Vol.29 (46), p.14571-14580

2009

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Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors

Annals of oncology, 2014-03, Vol.25 (3), p.552-563

2014

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Protein arginine methyltransferase 5 is essential for growth of lung cancer cells

Biochemical journal, 2012-09, Vol.446 (2), p.235-241

2012

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Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma

FGF-dependent metabolic control of vascular development

In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia

Ensemble-Based Replica Exchange Alchemical Free Energy Methods: The Effect of Protein Mutations on Inhibitor Binding

A Tetravalent Bispecific Antibody Selectively Inhibits Diverse FGFR3 Oncogenic Variants

Characterization of membrane protein interactions in plasma membrane derived vesicles with quantitative imaging Förster resonance energy transfer

Sequential exposure to fibroblast growth factors (FGF) 2, 9 and 18 enhances hMSC chondrogenic differentiation

Effect of Thanatophoric Dysplasia Type I Mutations on FGFR3 Dimerization

Antitumor Activity of Tasurgratinib as an Orally Available FGFR1-3 Inhibitor in Cholangiocarcinoma Models With FGFR2-fusion

Kinase Activity of Fibroblast Growth Factor Receptor 3 Regulates Activity of the Papillomavirus E2 Protein

Amplification of FRS2 and Activation of FGFR/FRS2 Signaling Pathway in High-Grade Liposarcoma

Biomarker-Oriented Therapy in Bladder and Renal Cancer

Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer

A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model

Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia

Selective over-expression of fibroblast growth factor receptors 1 and 4 in clinical prostate cancer

Futibatinib Is a Novel Irreversible FGFR 1-4 Inhibitor That Shows Selective Antitumor Activity against FGFR-Deregulated Tumors

Exploring mechanisms of FGF signalling through the lens of structural biology

Genetically confirmed thanatophoric dysplasia with fibroblast growth factor receptor 3 mutation

Pemigatinib: First Approval

Ligand-associated ERBB2/3 activation confers acquired resistance to FGFR inhibition in FGFR3-dependent cancer cells

Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance

The Transition from Radial Glial to Intermediate Progenitor Cell Is Inhibited by FGF Signaling during Corticogenesis

Genomic aberrations in the FGFR pathway: opportunities for targeted therapies in solid tumors

Protein arginine methyltransferase 5 is essential for growth of lung cancer cells

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