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Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase

Journal of medicinal chemistry, 2001-09, Vol.44 (19), p.3195-3198

2001

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Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors

Journal of medicinal chemistry, 2011-12, Vol.54 (24), p.8271-8277

2011

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Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.335-344

2010

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Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4‑Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors

Journal of medicinal chemistry, 2016-06, Vol.59 (12), p.5721-5739

2016

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Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases

Journal of medicinal chemistry, 2013-01, Vol.56 (1), p.293-300

2013

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Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents

Journal of medicinal chemistry, 2016-07, Vol.59 (14), p.6791-6806

2016

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Identification of 6‑Fluorine-Substituted Coumarin Analogues as POLRMT Inhibitors with High Potency and Safety for Treatment of Pancreatic Cancer

Journal of medicinal chemistry, 2024-08, Vol.67 (15), p.13231-13251

2024

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Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.7206-7212

2017

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Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR‑2 as Potential Agents for Solid Tumors: X‑ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles

Journal of medicinal chemistry, 2024-05, Vol.67 (9), p.7406-7430

2024

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Synthesis of Heterocyclic Ring-Fused Bisnoralcohol Derivatives as Novel Small-Molecule Antiosteoporosis Agents

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.8271-8295

2024

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Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance

Journal of medicinal chemistry, 2024-08, Vol.67 (15), p.12601-12617

2024

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Structure−Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle−Coumarin Conjugates

Journal of medicinal chemistry, 2009-03, Vol.52 (5), p.1486-1490

2009

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A Selective Galactose–Coumarin-Derived Galectin‑3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.8141-8147

2016

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Synthesis and in Vitro Photocytotoxicity of Coumarin Derivatives for One- and Two-Photon Excited Photodynamic Therapy

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5288-5294

2013

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Synthesis and Biological Investigation of Coumarin Piperazine (Piperidine) Derivatives as Potential Multireceptor Atypical Antipsychotics

Journal of medicinal chemistry, 2013-06, Vol.56 (11), p.4671-4690

2013

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Synthesis and Electrochemical and Biological Studies of Novel Coumarin–Chalcone Hybrid Compounds

Journal of medicinal chemistry, 2013-08, Vol.56 (15), p.6136-6145

2013

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Synthesis and Study of a Series of 3-Arylcoumarins as Potent and Selective Monoamine Oxidase B Inhibitors

Journal of medicinal chemistry, 2011-10, Vol.54 (20), p.7127-7137

2011

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Synthesis and Antiinflammatory Activity of Coumarin Derivatives

Journal of medicinal chemistry, 2005-10, Vol.48 (20), p.6400-6408

2005

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Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups

Journal of medicinal chemistry, 2014-11, Vol.57 (21), p.9152-9167

2014

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Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex

Journal of medicinal chemistry, 2012-12, Vol.55 (24), p.11013-11021

2012

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Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Aromatase Inhibitors Selective over 17-α-Hydroxylase/C17−20 Lyase

Journal of medicinal chemistry, 2011-03, Vol.54 (6), p.1613-1625

2011

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Discovery of Coumarin–Dihydropyridine Hybrids as Bone Anabolic Agents

Journal of medicinal chemistry, 2013-01, Vol.56 (1), p.109-122

2013

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Synthesis and Biological Evaluation of 4-Arylcoumarin Analogues of Combretastatins. Part 2

Journal of medicinal chemistry, 2011-05, Vol.54 (9), p.3153-3162

2011

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Synthesis, Molecular Modeling, and Selective Inhibitory Activity against Human Monoamine Oxidases of 3-Carboxamido-7-Substituted Coumarins

Journal of medicinal chemistry, 2009-04, Vol.52 (7), p.1935-1942

2009

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Design, Synthesis, and Evaluation of Coumarin-Based Molecular Probes for Imaging of Myelination

Journal of medicinal chemistry, 2011-04, Vol.54 (7), p.2331-2340

2011

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Coumarins Derivatives as Dual Inhibitors of Acetylcholinesterase and Monoamine Oxidase

Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors

Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins

Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4‑Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors

Sulfocoumarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases

Exploring Basic Tail Modifications of Coumarin-Based Dual Acetylcholinesterase-Monoamine Oxidase B Inhibitors: Identification of Water-Soluble, Brain-Permeant Neuroprotective Multitarget Agents

Identification of 6‑Fluorine-Substituted Coumarin Analogues as POLRMT Inhibitors with High Potency and Safety for Treatment of Pancreatic Cancer

Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?

Discovery and Mechanistic Studies of Dual-Target Hits for Carbonic Anhydrase IX and VEGFR‑2 as Potential Agents for Solid Tumors: X‑ray, In Vitro, In Vivo, and In Silico Investigations of Coumarin-Based Thiazoles

Synthesis of Heterocyclic Ring-Fused Bisnoralcohol Derivatives as Novel Small-Molecule Antiosteoporosis Agents

Discovery of Novel α,β-Unsaturated Amide Derivatives as Candidate Antifungals to Overcome Fungal Resistance

Structure−Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle−Coumarin Conjugates

A Selective Galactose–Coumarin-Derived Galectin‑3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model

Synthesis and in Vitro Photocytotoxicity of Coumarin Derivatives for One- and Two-Photon Excited Photodynamic Therapy

Synthesis and Biological Investigation of Coumarin Piperazine (Piperidine) Derivatives as Potential Multireceptor Atypical Antipsychotics

Synthesis and Electrochemical and Biological Studies of Novel Coumarin–Chalcone Hybrid Compounds

Synthesis and Study of a Series of 3-Arylcoumarins as Potent and Selective Monoamine Oxidase B Inhibitors

Synthesis and Antiinflammatory Activity of Coumarin Derivatives

Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups

Dual Targeting of Hypoxic and Acidic Tumor Environments with a Cobalt(III) Chaperone Complex

Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Aromatase Inhibitors Selective over 17-α-Hydroxylase/C17−20 Lyase

Discovery of Coumarin–Dihydropyridine Hybrids as Bone Anabolic Agents

Synthesis and Biological Evaluation of 4-Arylcoumarin Analogues of Combretastatins. Part 2

Synthesis, Molecular Modeling, and Selective Inhibitory Activity against Human Monoamine Oxidases of 3-Carboxamido-7-Substituted Coumarins

Design, Synthesis, and Evaluation of Coumarin-Based Molecular Probes for Imaging of Myelination

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