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Adipose Tissue-Derived Factors: Impact on Health and Disease

Endocrine reviews, 2006-12, Vol.27 (7), p.762-778

2006

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Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans

Diabetes (New York, N.Y.), 2007-04, Vol.56 (4), p.1010-1013

2007

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Adipocyte, Adipose Tissue, and Infectious Disease

Infection and immunity, 2007-03, Vol.75 (3), p.1066-1078

2007

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Vericiguat, a novel sGC stimulator: Mechanism of action, clinical, and translational science

Clinical and translational science, 2023-12, Vol.16 (12), p.2458-2466

2023

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Epidemiology of Hepatitis C Virus in HIV Patients from West Mexico: Implications for Controlling and Preventing Viral Hepatitis

Pathogens (Basel), 2024-05, Vol.13 (5), p.360

2024

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GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production

PloS one, 2017-05, Vol.12 (5), p.e0176182-e0176182

2017

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GPR40 reduces food intake and body weight through GLP-1

American journal of physiology: endocrinology and metabolism, 2017-07, Vol.313 (1), p.E37-E47

2017

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Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients

Memórias do Instituto Oswaldo Cruz, 2015-04, Vol.110 (2), p.267-271

2015

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Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy

Nature medicine, 2005-07, Vol.11 (7), p.797-803

2005

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Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat

CPT: pharmacometrics and systems pharmacology, 2024-01, Vol.13 (1), p.79-92

2024

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Industrialization of Quantitative Systems Pharmacology

CPT: pharmacometrics and systems pharmacology, 2019-06, Vol.8 (6), p.356-358

2019

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Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase

ACS medicinal chemistry letters, 2018-01, Vol.9 (1), p.39-44

2018

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Increase of drug use and genotype 3 in HCV-infected patients from Central West and Northeast Mexico

Annals of hepatology, 2015-09, Vol.14 (5), p.642-651

2015

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Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

Clinical pharmacokinetics, 2023-11, Vol.62 (11), p.1639-1648

2023

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Clinical Pharmacokinetic and Pharmacodynamic Profile of Vericiguat

Clinical pharmacokinetics, 2024-06, Vol.63 (6), p.751-771

2024

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Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

Molecular and Cellular Biology, 2009-08, Vol.29 (16), p.4467-4483

2009

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Obese Mice Lacking Inducible Nitric Oxide Synthase Are Sensitized to the Metabolic Actions of Peroxisome Proliferator–Activated Receptor-γ Agonism

Diabetes (New York, N.Y.), 2008-08, Vol.57 (8), p.1999-2011

2008

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Structure–Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.685-690

2018

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Population Pharmacokinetics of Vericiguat in Patients With Heart Failure With Reduced Ejection Fraction: An Integrated Analysis

Clinical pharmacology and therapeutics, 2022-11, Vol.112 (5), p.1061-1069

2022

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Obesity-associated improvements in metabolic profile through expansion of adipose tissue

The Journal of clinical investigation, 2007-09, Vol.117 (9), p.2621-2637

2007

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GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

Molecular metabolism (Germany), 2015-01, Vol.4 (1), p.3-14

2015

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Hit-to-Lead Optimization and Discovery of 5‑((5-([1,1′-Biphenyl]-4-yl)-6-chloro‑1H‑benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase

Journal of medicinal chemistry, 2017-11, Vol.60 (21), p.9040-9052

2017

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Adipocyte, adipose tissue, and infectious disease

Infection and immunity, 2007-03, Vol.75 (3), p.1066-1078

2007

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Obstetric and fetal outcomes in dystocic and eutocic sows to an injection of exogenous oxytocin during farrowing

Canadian veterinary journal, 2009-12, Vol.50 (12), p.1273-1277

2009

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Interleukin-6 Regulates Human Adipose Tissue Lipid Metabolism and Leptin Production in Vitro

The journal of clinical endocrinology and metabolism, 2004-11, Vol.89 (11), p.5577-5582

2004

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Adipose Tissue-Derived Factors: Impact on Health and Disease

Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans

Adipocyte, Adipose Tissue, and Infectious Disease

Vericiguat, a novel sGC stimulator: Mechanism of action, clinical, and translational science

Epidemiology of Hepatitis C Virus in HIV Patients from West Mexico: Implications for Controlling and Preventing Viral Hepatitis

GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production

GPR40 reduces food intake and body weight through GLP-1

Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients

Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy

Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat

Industrialization of Quantitative Systems Pharmacology

Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase

Increase of drug use and genotype 3 in HCV-infected patients from Central West and Northeast Mexico

Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches

Clinical Pharmacokinetic and Pharmacodynamic Profile of Vericiguat

Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue

Obese Mice Lacking Inducible Nitric Oxide Synthase Are Sensitized to the Metabolic Actions of Peroxisome Proliferator–Activated Receptor-γ Agonism

Structure–Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs

Population Pharmacokinetics of Vericiguat in Patients With Heart Failure With Reduced Ejection Fraction: An Integrated Analysis

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

GPR40 (FFAR1) – Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo

Hit-to-Lead Optimization and Discovery of 5‑((5-([1,1′-Biphenyl]-4-yl)-6-chloro‑1H‑benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic Acid (MK-3903): A Novel Class of Benzimidazole-Based Activators of AMP-Activated Protein Kinase

Adipocyte, adipose tissue, and infectious disease

Obstetric and fetal outcomes in dystocic and eutocic sows to an injection of exogenous oxytocin during farrowing

Interleukin-6 Regulates Human Adipose Tissue Lipid Metabolism and Leptin Production in Vitro

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