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Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist

The Journal of pharmacology and experimental therapeutics, 2006-05, Vol.317 (2), p.910

2006

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Identification and characterization of novel NMDA receptor antagonists selective for NR2A- over NR2B-containing receptors

The Journal of pharmacology and experimental therapeutics, 2010-12, Vol.335 (3), p.636-644

2010

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GluN2D N-Methyl-d-Aspartate Receptor Subunit Contribution to the Stimulation of Brain Activity and Gamma Oscillations by Ketamine: Implications for Schizophrenia

The Journal of pharmacology and experimental therapeutics, 2016-03, Vol.356 (3), p.702-711

2016

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Buprenorphine and opioid antagonism, tolerance, and naltrexone-precipitated withdrawal

The Journal of pharmacology and experimental therapeutics, 2011-02, Vol.336 (2), p.488-495

2011

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Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice

The Journal of pharmacology and experimental therapeutics, 2008-05, Vol.325 (2), p.500-506

2008

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Stronger antinociceptive efficacy of opioids at the injured nerve trunk than at its peripheral terminals in neuropathic pain

The Journal of pharmacology and experimental therapeutics, 2013-09, Vol.346 (3), p.535-544

2013

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A Glutamate N -Methyl-d-Aspartate (NMDA) Receptor Subunit 2B-Selective Inhibitor of NMDA Receptor Function with Enhanced Potency at Acidic pH and Oral Bioavailability for Clinical Use

The Journal of pharmacology and experimental therapeutics, 2021-10, Vol.379 (1), p.41-52

2021

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Enhanced vascular neuronal nitric-oxide synthase-derived nitric-oxide production underlies the pressor response caused by peripheral N-methyl-D-aspartate receptor activation in conscious rats

The Journal of pharmacology and experimental therapeutics, 2012-08, Vol.342 (2), p.461-471

2012

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Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression

The Journal of pharmacology and experimental therapeutics, 2017-04, Vol.361 (1), p.68-86

2017

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Selective Inhibition of N -Methyl-d-aspartate Receptors with GluN2B Subunit Protects β Cells against Stress-Induced Apoptotic Cell Death

The Journal of pharmacology and experimental therapeutics, 2021-12, Vol.379 (3), p.235-244

2021

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Aberrant synaptic activation of N-methyl-D-aspartate receptors underlies ethanol withdrawal hyperexcitability

The Journal of pharmacology and experimental therapeutics, 2007-04, Vol.321 (1), p.60-72

2007

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Interactions between bupropion and 3,4-methylenedioxymethamphetamine in healthy subjects

The Journal of pharmacology and experimental therapeutics, 2015-04, Vol.353 (1), p.102-111

2015

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Pharmacological interaction between 3,4-methylenedioxymethamphetamine (ecstasy) and paroxetine: pharmacological effects and pharmacokinetics

The Journal of pharmacology and experimental therapeutics, 2007-12, Vol.323 (3), p.954-962

2007

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Studies of (±)-3,4-methylenedioxymethamphetamine (MDMA) metabolism and disposition in rats and mice: relationship to neuroprotection and neurotoxicity profile

The Journal of pharmacology and experimental therapeutics, 2013-02, Vol.344 (2), p.479-488

2013

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Functional selectivity of kappa opioid receptor agonists in peripheral sensory neurons

The Journal of pharmacology and experimental therapeutics, 2015-11, Vol.355 (2), p.174-182

2015

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Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats

The Journal of pharmacology and experimental therapeutics, 2008-07, Vol.326 (1), p.218-229

2008

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N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement

The Journal of pharmacology and experimental therapeutics, 2013-11, Vol.347 (2), p.438-457

2013

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Effects of Repeated Ropinirole Treatment on Phencyclidine-Induced Hyperlocomotion, Prepulse Inhibition Deficits, and Social Avoidance in Rats

The Journal of pharmacology and experimental therapeutics, 2017-04, Vol.361 (1), p.109-114

2017

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Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

The Journal of pharmacology and experimental therapeutics, 2003-12, Vol.307 (3), p.906-922

2003

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Opioid receptor subtypes differentially modulate serotonin efflux in the rat central nervous system

The Journal of pharmacology and experimental therapeutics, 2002-11, Vol.303 (2), p.549-556

2002

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N-methyl-D-aspartate receptor channel blocker-like discriminative stimulus effects of nitrous oxide gas

The Journal of pharmacology and experimental therapeutics, 2015-01, Vol.352 (1), p.156-165

2015

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Phosphorylation of the N-methyl-d-aspartate receptor is increased in the nucleus accumbens during both acute and extended morphine withdrawal

The Journal of pharmacology and experimental therapeutics, 2015-12, Vol.355 (3), p.496-505

2015

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Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker

The Journal of pharmacology and experimental therapeutics, 2010-08, Vol.334 (2), p.545-555

2010

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The radical trap 5,5-dimethyl-1-pyrroline N-oxide exerts dose-dependent protection against myocardial ischemia-reperfusion injury through preservation of mitochondrial electron transport

The Journal of pharmacology and experimental therapeutics, 2009-05, Vol.329 (2), p.515-523

2009

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Behavioral effects and pharmacokinetics of (±)-3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) after intragastric administration to baboons

The Journal of pharmacology and experimental therapeutics, 2013-06, Vol.345 (3), p.342-353

2013

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Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist

Identification and characterization of novel NMDA receptor antagonists selective for NR2A- over NR2B-containing receptors

GluN2D N-Methyl-d-Aspartate Receptor Subunit Contribution to the Stimulation of Brain Activity and Gamma Oscillations by Ketamine: Implications for Schizophrenia

Buprenorphine and opioid antagonism, tolerance, and naltrexone-precipitated withdrawal

Unexceptional seizure potential of tramadol or its enantiomers or metabolites in mice

Stronger antinociceptive efficacy of opioids at the injured nerve trunk than at its peripheral terminals in neuropathic pain

A Glutamate N -Methyl-d-Aspartate (NMDA) Receptor Subunit 2B-Selective Inhibitor of NMDA Receptor Function with Enhanced Potency at Acidic pH and Oral Bioavailability for Clinical Use

Enhanced vascular neuronal nitric-oxide synthase-derived nitric-oxide production underlies the pressor response caused by peripheral N-methyl-D-aspartate receptor activation in conscious rats

Comparative Effects of LY3020371, a Potent and Selective Metabotropic Glutamate (mGlu) 2/3 Receptor Antagonist, and Ketamine, a Noncompetitive N -Methyl-d-Aspartate Receptor Antagonist in Rodents: Evidence Supporting the Use of mGlu2/3 Antagonists, for the Treatment of Depression

Selective Inhibition of N -Methyl-d-aspartate Receptors with GluN2B Subunit Protects β Cells against Stress-Induced Apoptotic Cell Death

Aberrant synaptic activation of N-methyl-D-aspartate receptors underlies ethanol withdrawal hyperexcitability

Interactions between bupropion and 3,4-methylenedioxymethamphetamine in healthy subjects

Pharmacological interaction between 3,4-methylenedioxymethamphetamine (ecstasy) and paroxetine: pharmacological effects and pharmacokinetics

Studies of (±)-3,4-methylenedioxymethamphetamine (MDMA) metabolism and disposition in rats and mice: relationship to neuroprotection and neurotoxicity profile

Functional selectivity of kappa opioid receptor agonists in peripheral sensory neurons

Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement

Effects of Repeated Ropinirole Treatment on Phencyclidine-Induced Hyperlocomotion, Prepulse Inhibition Deficits, and Social Avoidance in Rats

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

Opioid receptor subtypes differentially modulate serotonin efflux in the rat central nervous system

N-methyl-D-aspartate receptor channel blocker-like discriminative stimulus effects of nitrous oxide gas

Phosphorylation of the N-methyl-d-aspartate receptor is increased in the nucleus accumbens during both acute and extended morphine withdrawal

Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker

The radical trap 5,5-dimethyl-1-pyrroline N-oxide exerts dose-dependent protection against myocardial ischemia-reperfusion injury through preservation of mitochondrial electron transport

Behavioral effects and pharmacokinetics of (±)-3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) after intragastric administration to baboons

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