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Flavonoids: From Structure to Health Issues

Molecules (Basel, Switzerland), 2017-03, Vol.22 (3), p.477

2017

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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128214-128214, Article 128214

2021

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Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2979-2984

2018

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3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1292-1307

2019

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Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Bioorganic & medicinal chemistry letters, 2020-07, Vol.30 (13), p.127197-127197, Article 127197

2020

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Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115213, Article 115213

2020

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Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Bioorganic & medicinal chemistry, 2015-11, Vol.23 (21), p.6844-6854

2015

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Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (11), p.127143-127143, Article 127143

2020

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Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Bioorganic & medicinal chemistry letters, 2023-06, Vol.90, p.129331-129331, Article 129331

2023

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Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (21), p.3446-3453

2018

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Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors

Bioorganic chemistry, 2020-12, Vol.105, p.104447, Article 104447

2020

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Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (14), p.4209-4224

2018

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Design, synthesis, bioactivity and mechanism of dithioacetal derivatives containing dioxyether moiety

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2218-2223

2019

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Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2914-2919

2018

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Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives

Bioorganic & medicinal chemistry, 2018-08, Vol.26 (15), p.4452-4460

2018

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Chemical structure of hydrolysates of cereulide and their time course profile

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (9), p.127050-127050, Article 127050

2020

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Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1283-1291

2019

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Development of pyrimidone D1 dopamine receptor positive allosteric modulators

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127696-127696, Article 127696

2021

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Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128168-128168, Article 128168

2021

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Syntheses, antiviral activities and induced resistance mechanisms of novel quinazoline derivatives containing a dithioacetal moiety

Bioorganic chemistry, 2018-10, Vol.80, p.433-443

2018

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Indirubin-3′-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction

Bioorganic chemistry, 2022-04, Vol.121, p.105664-105664, Article 105664

2022

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Synthesis and biological evaluation of novel aromatic amide derivatives as potential BCR-ABL inhibitors

Bioorganic & medicinal chemistry letters, 2023-02, Vol.81, p.129144-129144, Article 129144

2023

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Discovery of novel pan-genotypic HCV NS5A inhibitors containing a novel tetracyclic core

Bioorganic & medicinal chemistry letters, 2019-03, Vol.29 (5), p.700-706

2019

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Design, synthesis and biological evaluation of a series of iron and copper chelating deferiprone derivatives as new agents active against Candida albicans

Bioorganic & medicinal chemistry letters, 2021-06, Vol.42, p.128087, Article 128087

2021

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Design, synthesis and biological evaluation of fucose-truncated monosaccharide analogues of ipomoeassin F

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2752-2756

2017

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1 – 25 von 18.474

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Flavonoids: From Structure to Health Issues

SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives

Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Synthesis, biological evaluation, and molecular docking analysis of phenstatin based indole linked chalcones as anticancer agents and tubulin polymerization inhibitors

Synthesis and anticancer activity of novel bisindolylhydroxymaleimide derivatives with potent GSK-3 kinase inhibition

Design, synthesis, bioactivity and mechanism of dithioacetal derivatives containing dioxyether moiety

Synthesis and antimicrobial studies of hydrazone derivatives of 4-[3-(2,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid and 4-[3-(3,4-difluorophenyl)-4-formyl-1H-pyrazol-1-yl]benzoic acid

Cytotoxic and NF-κB and mitochondrial transmembrane potential inhibitory pentacyclic triterpenoids from Syzygium corticosum and their semi-synthetic derivatives

Chemical structure of hydrolysates of cereulide and their time course profile

Structure-activity relationships for unit C pyridyl analogues of the tuberculosis drug bedaquiline

Development of pyrimidone D1 dopamine receptor positive allosteric modulators

Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Syntheses, antiviral activities and induced resistance mechanisms of novel quinazoline derivatives containing a dithioacetal moiety

Indirubin-3′-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction

Synthesis and biological evaluation of novel aromatic amide derivatives as potential BCR-ABL inhibitors

Discovery of novel pan-genotypic HCV NS5A inhibitors containing a novel tetracyclic core

Design, synthesis and biological evaluation of a series of iron and copper chelating deferiprone derivatives as new agents active against Candida albicans

Design, synthesis and biological evaluation of fucose-truncated monosaccharide analogues of ipomoeassin F

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