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Structure-activity relationships of GPR120 agonists based on a docking simulation

Molecular pharmacology, 2010-11, Vol.78 (5), p.804-810

2010

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DHA supplementation prevent the progression of NASH via GPR120 signaling

European journal of pharmacology, 2018-02, Vol.820, p.31-38

2018

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Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Biochemical pharmacology, 2023-07, Vol.213, p.115590-115590, Article 115590

2023

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Positive interplay between FFAR4/GPR120, DPP-IV inhibition and GLP-1 in beta cell proliferation and glucose homeostasis in obese high fat fed mice

Peptides (New York, N.Y. : 1980), 2024-07, Vol.177, p.171218, Article 171218

2024

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Free fatty acid receptors as therapeutic targets for the treatment of diabetes

Frontiers in pharmacology, 2014-11, Vol.5, p.236-236

2014

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In silico and in vitro screening for potential anticancer candidates targeting GPR120

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127672, Article 127672

2021

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Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Frontiers in pharmacology, 2023-07, Vol.14, p.1197743-1197743

2023

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GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Biomedicine & pharmacotherapy, 2023-12, Vol.168, p.115774-115774, Article 115774

2023

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Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

Peptides (New York, N.Y. : 1980), 2020-12, Vol.134, p.170419-170419, Article 170419

2020

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GPR120 promotes radiation resistance in esophageal cancer via regulating AKT and apoptosis pathway

Anti-cancer drugs, 2021-01, Vol.32 (1), p.53-60

2021

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Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages

European journal of pharmacology, 2016-08, Vol.785, p.36-43

Im, Dong-Soon

2016

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Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

Biochemical pharmacology, 2022-12, Vol.206, p.115328, Article 115328

2022

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Identification and target-pathway deconvolution of FFA4 agonists with anti-diabetic activity from Arnebia euchroma (Royle) Johnst

Pharmacological research, 2021-01, Vol.163, p.105173-105173, Article 105173

2021

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Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)

Bioorganic & medicinal chemistry letters, 2014-07, Vol.24 (14), p.3100-3103

2014

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Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders

Biochemical pharmacology, 2016-06, Vol.110-111, p.1-15

Moniri, Nader H.

2016

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Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development

Expert opinion on investigational drugs, 2016-08, Vol.25 (8), p.871-890

2016

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Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design

Bioorganic & medicinal chemistry letters, 2018-08, Vol.28 (15), p.2599-2604

2018

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Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics

Current medicinal chemistry, 2013-10, Vol.20 (31), p.3855-3871

2013

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Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action

ACS medicinal chemistry letters, 2022-12, Vol.13 (12), p.1839-1847

2022

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Activation of GPR120 by TUG891 ameliorated cisplatin-induced acute kidney injury via repressing ER stress and apoptosis

Biomedicine & pharmacotherapy, 2020-06, Vol.126, p.110056, Article 110056

2020

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Free fatty acid receptor 4 (FFA4) activation attenuates obese asthma by suppressing adiposity and resolving metaflammation

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116509-116509, Article 116509

2024

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Development of Free Fatty Acid Receptor 4 (FFA4/GPR120) Agonists in Health Science

Biomolecules & Therapeutics, 2021, 29(1), , pp.22-30

2021

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A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

Biomedicine & pharmacotherapy, 2021-07, Vol.139, p.111613-111613, Article 111613

2021

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The role of free-fatty acid receptor-4 (FFA4) in human cancers and cancer cell lines

Biochemical pharmacology, 2018-04, Vol.150, p.170-180

2018

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Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists

Bioorganic & medicinal chemistry letters, 2020-12, Vol.30 (24), p.127650-127650, Article 127650

2020

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Structure-activity relationships of GPR120 agonists based on a docking simulation

DHA supplementation prevent the progression of NASH via GPR120 signaling

Free-Fatty Acid Receptor-4 (FFA4/GPR120) differentially regulates migration, invasion, proliferation and tumor growth of papillary renal cell carcinoma cells

Positive interplay between FFAR4/GPR120, DPP-IV inhibition and GLP-1 in beta cell proliferation and glucose homeostasis in obese high fat fed mice

Free fatty acid receptors as therapeutic targets for the treatment of diabetes

In silico and in vitro screening for potential anticancer candidates targeting GPR120

Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

GPR120/FFAR4 stimulation attenuates airway remodeling and suppresses IL-4- and IL-13-induced airway epithelial injury via inhibition of STAT6 and Akt

Dipeptidyl peptidase-4 and GLP-1 interplay in STC-1 and GLUTag cell lines

GPR120 promotes radiation resistance in esophageal cancer via regulating AKT and apoptosis pathway

Functions of omega-3 fatty acids and FFA4 (GPR120) in macrophages

Oncogenic signaling of the free-fatty acid receptors FFA1 and FFA4 in human breast carcinoma cells

Identification and target-pathway deconvolution of FFA4 agonists with anti-diabetic activity from Arnebia euchroma (Royle) Johnst

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)

Free-fatty acid receptor-4 (GPR120): Cellular and molecular function and its role in metabolic disorders

Free fatty acid receptor agonists for the treatment of type 2 diabetes: drugs in preclinical to phase II clinical development

Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design

Free fatty acids-sensing G protein-coupled receptors in drug targeting and therapeutics

Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action

Activation of GPR120 by TUG891 ameliorated cisplatin-induced acute kidney injury via repressing ER stress and apoptosis

Free fatty acid receptor 4 (FFA4) activation attenuates obese asthma by suppressing adiposity and resolving metaflammation

Development of Free Fatty Acid Receptor 4 (FFA4/GPR120) Agonists in Health Science

A new synthetic dual agonist of GPR120/GPR40 induces GLP-1 secretion and improves glucose homeostasis in mice

The role of free-fatty acid receptor-4 (FFA4) in human cancers and cancer cell lines

Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists

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