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Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

The New England journal of medicine, 2015-02, Vol.372 (6), p.509-518

2015

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Successes and challenges of HIV prevention in men who have sex with men

The Lancet (British edition), 2012-07, Vol.380 (9839), p.388-399

2012

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A topical rectal douche product containing Q-Griffithsin does not disrupt the epithelial border or alter CD4 + cell distribution in the human rectal mucosa

Scientific reports, 2023-05, Vol.13 (1), p.7547-7547, Article 7547

2023

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A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007)

PloS one, 2013-04, Vol.8 (4), p.e60147

2013

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An Open-Label Pharmacokinetic and Pharmacodynamic Assessment of Tenofovir Gel and Oral Emtricitabine/Tenofovir Disoproxil Fumarate

AIDS research and human retroviruses, 2022-04, Vol.38 (4), p.279-287

2022

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Reverse Transcriptase Inhibitors as Potential Colorectal Microbicides

Antimicrobial Agents and Chemotherapy, 2009-05, Vol.53 (5), p.1797-1807

2009

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A multi-compartment single and multiple dose pharmacokinetic comparison of rectally applied tenofovir 1% gel and oral tenofovir disoproxil fumarate

PloS one, 2014-10, Vol.9 (10), p.e106196

2014

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Human Semen or Seminal Plasma Does Not Enhance HIV-1 BaL Ex Vivo Infection of Human Colonic Explants

AIDS research and human retroviruses, 2018-05, Vol.34 (5), p.459-466

2018

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A Randomized, Open-Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study)

AIDS research and human retroviruses, 2022-04, Vol.38 (4), p.269-278

2022

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Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel

PLoS medicine, 2008-08, Vol.5 (8), p.e157; discussion e157-e157

2008

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The development of rectal microbicides for HIV prevention

Expert opinion on drug delivery, 2014-01, Vol.11 (1), p.69-82

McGowan, Ian

2014

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Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice

PloS one, 2013-03, Vol.8 (3), p.e60024-e60024

2013

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First phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy

PloS one, 2011-09, Vol.6 (9), p.e23243

2011

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Safety and Pharmacokinetics of a Tenofovir Alafenamide Fumarate-Emtricitabine based Oral Antiretroviral Regimen for Prevention of HIV Acquisition in Women: A Randomized Controlled Trial

EClinicalMedicine, 2021-06, Vol.36, p.100893, Article 100893

2021

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Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study

PloS one, 2014-10, Vol.9 (10), p.e111507

2014

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Rectal Microbicides: Can We Make Them and Will People Use Them?

AIDS and behavior, 2011-04, Vol.15 (Suppl 1), p.66-71

McGowan, Ian

2011

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An Overview of Antiretroviral Pre-Exposure Prophylaxis of HIV Infection

American journal of reproductive immunology (1989), 2014-06, Vol.71 (6), p.624-630

McGowan, Ian

2014

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Phase I/II Trial of the Pharmacokinetics, Safety, and Antiretroviral Activity of Tenofovir Disoproxil Fumarate in Human Immunodeficiency Virus-Infected Adults

Antimicrobial Agents and Chemotherapy, 2001-10, Vol.45 (10), p.2733-2739

2001

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Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women

PloS one, 2016-06, Vol.11 (6), p.e0158310-e0158310

2016

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Mucosal effects of tenofovir 1% gel

eLife, 2015-02, Vol.4

2015

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Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials

PloS one, 2015-05, Vol.10 (5), p.e0126454-e0126454

2015

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Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

Successes and challenges of HIV prevention in men who have sex with men

Safety, immunogenicity and effect on viral rebound of HTI vaccines in early treated HIV-1 infection: a randomized, placebo-controlled phase 1 trial

A topical rectal douche product containing Q-Griffithsin does not disrupt the epithelial border or alter CD4 + cell distribution in the human rectal mucosa

A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007)

An Open-Label Pharmacokinetic and Pharmacodynamic Assessment of Tenofovir Gel and Oral Emtricitabine/Tenofovir Disoproxil Fumarate

Reverse Transcriptase Inhibitors as Potential Colorectal Microbicides

A multi-compartment single and multiple dose pharmacokinetic comparison of rectally applied tenofovir 1% gel and oral tenofovir disoproxil fumarate

Human Semen or Seminal Plasma Does Not Enhance HIV-1 BaL Ex Vivo Infection of Human Colonic Explants

A Randomized, Open-Label, Crossover Phase 1 Safety and Pharmacokinetic Study of Oral Maraviroc and Maraviroc 1% Gel (the CHARM-03 Study)

A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study)

Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gel

The development of rectal microbicides for HIV prevention

Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice

First phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy

High levels of adherence to a rectal microbicide gel and to oral Pre-Exposure Prophylaxis (PrEP) achieved in MTN-017 among men who have sex with men (MSM) and transgender women

Safety and Pharmacokinetics of a Tenofovir Alafenamide Fumarate-Emtricitabine based Oral Antiretroviral Regimen for Prevention of HIV Acquisition in Women: A Randomized Controlled Trial

Correlation between compartmental tenofovir concentrations and an ex vivo rectal biopsy model of tissue infectibility in the RMP-02/MTN-006 phase 1 study

Rectal Microbicides: Can We Make Them and Will People Use Them?

An Overview of Antiretroviral Pre-Exposure Prophylaxis of HIV Infection

Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment

Phase I/II Trial of the Pharmacokinetics, Safety, and Antiretroviral Activity of Tenofovir Disoproxil Fumarate in Human Immunodeficiency Virus-Infected Adults

Project Gel a Randomized Rectal Microbicide Safety and Acceptability Study in Young Men and Transgender Women

Mucosal effects of tenofovir 1% gel

Exploring the feasibility of multi-site flow cytometric processing of gut associated lymphoid tissue with centralized data analysis for multi-site clinical trials

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