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Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

Oncogene, 2010-02, Vol.29 (5), p.687-697

2010

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Understanding PTEN regulation: PIP2, polarity and protein stability

Oncogene, 2008-09, Vol.27 (41), p.5464-5476

2008

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Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities

Biochemical journal, 2000-10, Vol.351 (Pt 1), p.19-31

2000

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Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells

Diabetologia, 2001-02, Vol.44 (2), p.173-183

2001

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Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling

Oncogene, 2007-11, Vol.26 (50), p.7132-7142

2007

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The role of PI 3-kinase in insulin action

BBA - Molecular and Cell Biology of Lipids, 1998-12, Vol.1436 (1), p.151-164

1998

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Cellular responses to stress

2014

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Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components

Biochemical journal, 2000-10, Vol.351 (Pt 1), p.173-182

2000

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A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation

The Journal of experimental medicine, 2002-09, Vol.196 (6), p.753-763

2002

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Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN

Current biology, 2001-05, Vol.11 (10), p.764-768

2001

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Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells

The Journal of biological chemistry, 1992-07, Vol.267 (21), p.14563-14567

1992

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Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions

Biochemical journal, 2001-07, Vol.357 (Pt 2), p.427-435

2001

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PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2

Current biology, 1999-04, Vol.9 (8), p.393-404

1999

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Redox regulation of phosphatase function

Biochemical Society transactions, 2004-12, Vol.32 (Pt 6), p.1018-1020

2004

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Acute regulation of the tumour suppressor phosphatase, PTEN, by anionic lipids and reactive oxygen species

Biochemical Society transactions, 2004-04, Vol.32 (Pt 2), p.338-342

2004

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Activation of phospholipase D by metabotropic glutamate receptor agonists in rat cerebrocortical synaptosomes

British journal of pharmacology, 2000-11, Vol.131 (5), p.1011-1018

2000

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A G-protein beta gamma-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol

The Journal of biological chemistry, 1994-06, Vol.269 (24), p.16525-16528

1994

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Kinetics of Activation of Phospholipase C by P2Y Purinergic Receptor Agonists and Guanine Nucleotides

The Journal of biological chemistry, 1989-01, Vol.264 (2), p.884-890

1989

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Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

Biochemical journal, 1982-09, Vol.206 (3), p.587-595

1982

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The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo

Biochemical journal, 1999-12, Vol.344 Pt 3 (3), p.929-936

1999

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Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

Biochemical journal, 1983-05, Vol.212 (2), p.473-482

1983

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Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

Biochemical journal, 1999-02, Vol.337 ( Pt 3) (3), p.575-583

1999

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The Role of Dynamin and Its Binding Partners in Coated Pit Invagination and Scission

The Journal of cell biology, 2001-01, Vol.152 (2), p.309-323

2001

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The inhibition of phosphoinositide synthesis and muscarinic-receptor-mediated phospholipase C activity by Li+ as secondary, selective consequences of inositol depletion in 1321N1 cells

Biochemical journal, 1994-02, Vol.297 (3), p.529-537

1994

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Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands

Biochemical journal, 1985-07, Vol.229 (2), p.505-511

1985

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Suppression of cellular proliferation and invasion by the concerted lipid and protein phosphatase activities of PTEN

Understanding PTEN regulation: PIP2, polarity and protein stability

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities

Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells

Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling

The role of PI 3-kinase in insulin action

Cellular responses to stress

Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components

A Crucial Role for the p110δ Subunit of Phosphatidylinositol 3-Kinase in B Cell Development and Activation

Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN

Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells

Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2

Redox regulation of phosphatase function

Acute regulation of the tumour suppressor phosphatase, PTEN, by anionic lipids and reactive oxygen species

Activation of phospholipase D by metabotropic glutamate receptor agonists in rat cerebrocortical synaptosomes

A G-protein beta gamma-subunit-responsive phosphoinositide 3-kinase activity in human platelet cytosol

Kinetics of Activation of Phospholipase C by P2Y Purinergic Receptor Agonists and Guanine Nucleotides

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

The pleckstrin homology domains of protein kinase B and GRP1 (general receptor for phosphoinositides-1) are sensitive and selective probes for the cellular detection of phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 3,4,5-trisphosphate in vivo

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

The Role of Dynamin and Its Binding Partners in Coated Pit Invagination and Scission

The inhibition of phosphoinositide synthesis and muscarinic-receptor-mediated phospholipase C activity by Li+ as secondary, selective consequences of inositol depletion in 1321N1 cells

Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands

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