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N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

Cell death and differentiation, 2017-03, Vol.24 (3), p.500-510

2017

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Modulating TRADD to restore cellular homeostasis and inhibit apoptosis

Nature (London), 2020-11, Vol.587 (7832), p.133-138

2020

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The TRAIL apoptotic pathway in cancer onset, progression and therapy

Nature reviews. Cancer, 2008-10, Vol.8 (10), p.782-798

2008

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Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

Cancer cell, 2014-08, Vol.26 (2), p.177-189

2014

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TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells

Arteriosclerosis, thrombosis, and vascular biology, 2007-05, Vol.27 (5), p.1101-1107

2007

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Non-canonical NF-κB signaling activation and regulation: principles and perspectives

Immunological reviews, 2011-11, Vol.244 (1), p.44-54

2011

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Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Journal of translational medicine, 2018-08, Vol.16 (1), p.242-8, Article 242

2018

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Blockade of CD40–TRAF2,3 or CD40–TRAF6 is sufficient to inhibit pro‐inflammatory responses in non‐haematopoietic cells

Immunology, 2015-01, Vol.144 (1), p.21-33

2015

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Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation

Molecular cell, 2010-04, Vol.38 (1), p.101-113

2010

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Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation

Molecular cell, 2017-02, Vol.65 (4), p.715-729.e5

2017

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Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (19), p.E3796-E3805

2017

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Tumor-necrosis-factor-related apoptosis-inducing ligand and the regulation of hematopoiesis

Current opinion in hematology, 2008-01, Vol.15 (1), p.42-48

2008

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Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions

Immunological reviews, 2011-11, Vol.244 (1), p.55-74

2011

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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

Cell, 2019-07, Vol.178 (3), p.585-599.e15

2019

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Exosomes derived from TRAIL-engineered mesenchymal stem cells with effective anti-tumor activity in a mouse melanoma model

International journal of pharmaceutics, 2018-10, Vol.549 (1-2), p.218-229

2018

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Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

Science (American Association for the Advancement of Science), 2014-07, Vol.345 (6192), p.98-101

2014

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Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors

Cancer research (Chicago, Ill.), 2021-06, Vol.81 (12), p.3402-3414

2021

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Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling

Gut, 2020-06, Vol.69 (6), p.1053-1063

2020

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Quercetin enhances apoptotic effect of tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer‐binding protein homologous protein (CHOP)‐death receptor 5 pathway

Cancer science, 2014-05, Vol.105 (5), p.520-527

2014

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Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways[S]

Molecular & cellular proteomics, 2019-06, Vol.18 (6), p.1138-1156

2019

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Ferroptosis‐inducing agents enhance TRAIL‐induced apoptosis through upregulation of death receptor 5

Journal of cellular biochemistry, 2019-01, Vol.120 (1), p.928-939

2019

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TNFR1-induced activation of the classical NF-κB pathway

The FEBS journal, 2011-04, Vol.278 (6), p.862-876

2011

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DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12687

2022

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Knockdown of miR-25 increases the sensitivity of liver cancer stem cells to TRAIL-induced apoptosis via PTEN/PI3K/Akt/Bad signaling pathway

International journal of oncology, 2016-12, Vol.49 (6), p.2600-2610

2016

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The Ubiquitin E3 Ligase TRAF6 Exacerbates Ischemic Stroke by Ubiquitinating and Activating Rac1

The Journal of neuroscience, 2017-12, Vol.37 (50), p.12123-12140

2017

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N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death

Modulating TRADD to restore cellular homeostasis and inhibit apoptosis

The TRAIL apoptotic pathway in cancer onset, progression and therapy

Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells

Non-canonical NF-κB signaling activation and regulation: principles and perspectives

Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Blockade of CD40–TRAF2,3 or CD40–TRAF6 is sufficient to inhibit pro‐inflammatory responses in non‐haematopoietic cells

Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation

Caspase-8 Acts in a Non-enzymatic Role as a Scaffold for Assembly of a Pro-inflammatory “FADDosome” Complex upon TRAIL Stimulation

Epithelial EZH2 serves as an epigenetic determinant in experimental colitis by inhibiting TNFα-mediated inflammation and apoptosis

Tumor-necrosis-factor-related apoptosis-inducing ligand and the regulation of hematopoiesis

Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold

Exosomes derived from TRAIL-engineered mesenchymal stem cells with effective anti-tumor activity in a mouse melanoma model

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis

Hexavalent TRAIL Fusion Protein Eftozanermin Alfa Optimally Clusters Apoptosis-Inducing TRAIL Receptors to Induce On-Target Antitumor Activity in Solid Tumors

Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling

Quercetin enhances apoptotic effect of tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer‐binding protein homologous protein (CHOP)‐death receptor 5 pathway

Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways[S]

Ferroptosis‐inducing agents enhance TRAIL‐induced apoptosis through upregulation of death receptor 5

TNFR1-induced activation of the classical NF-κB pathway

DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma

Knockdown of miR-25 increases the sensitivity of liver cancer stem cells to TRAIL-induced apoptosis via PTEN/PI3K/Akt/Bad signaling pathway

The Ubiquitin E3 Ligase TRAF6 Exacerbates Ischemic Stroke by Ubiquitinating and Activating Rac1

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