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Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease

Cell reports. Medicine, 2021-11, Vol.2 (11), p.100437-100437, Article 100437

2021

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Polygenic scores differentially predict developmental trajectories of subtypes of social withdrawal in childhood

Journal of child psychology and psychiatry, 2021-11, Vol.62 (11), p.1320-1329

2021

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Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study

Journal of translational medicine, 2023-01, Vol.21 (1), p.60-60, Article 60

2023

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Common pitfalls in drug target Mendelian randomization and how to avoid them

BMC medicine, 2024-10, Vol.22 (1), p.473-12, Article 473

2024

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Blood Levels of the SMOC1 Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study

Nutrients, 2021-11, Vol.13 (12), p.4208

2021

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Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease

Metabolites, 2022-05, Vol.12 (5), p.440

2022

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Large-scale metabolomic profiling and incident non-alcoholic fatty liver disease

iScience, 2023-07, Vol.26 (7), p.107127-107127, Article 107127

2023

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Genetic control of body weight by the human brain proteome

iScience, 2023-04, Vol.26 (4), p.106376-106376, Article 106376

2023

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Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases

Communications medicine, 2022-10, Vol.2 (1), p.130-130, Article 130

2022

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Impact of loss-of-function in angiopoietin-like 4 on the human phenome

Atherosclerosis, 2024-08, Vol.395

2024

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Drug target Mendelian randomization supports apolipoprotein C3-lowering for lipoprotein-lipid levels reductions and cardiovascular diseases prevention

Atherosclerosis, 2024-04, Vol.391, p.117501, Article 117501

2024

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Abstract 15687: Triglyceride Levels and Non-Alcoholic Fatty Liver Disease: A Multivariable Mendelian Randomization Study

Circulation (New York, N.Y.), 2022-11, Vol.146 (Suppl_1)

2022

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Abstract 12056: Angiopoietin-Like Protein 3 Blood Levels and Cardiometabolic Traits and Diseases: A Mendelian Randomization Study

Circulation (New York, N.Y.), 2022-11, Vol.146 (Suppl_1)

2022

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Body Fat Distribution, Fasting Insulin Levels, and Insulin Secretion: A Bidirectional Mendelian Randomization Study

The journal of clinical endocrinology and metabolism, 2023-06, Vol.108 (6), p.1308-1317

2023

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Disentangling the impact of gluteofemoral versus visceral fat accumulation on cardiometabolic health using sex-stratified Mendelian randomization

Atherosclerosis, 2023-12, Vol.386, p.117371-117371, Article 117371

2023

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Impact of loss-of-function in angiopoietin-like 4 on the human phenome

Atherosclerosis, 2024-06, Vol.393, p.117558, Article 117558

2024

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Pancreatitis polygenic risk score is independently associated with all-cause acute pancreatitis risk in the UK Biobank

Journal of gastroenterology and hepatology, 2024-10

2024

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Proteome-Wide Mendelian Randomization Identifies Causal Links Between Blood Proteins and Acute Pancreatitis

Gastroenterology (New York, N.Y. 1943), 2023-05, Vol.164 (6), p.953-965.e3

2023

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Association of multiple polygenic risk scores with myocardial infarction and atherosclerotic coronary artery lesions in a Canadian population

Atherosclerosis, 2024-08, Vol.395

2024

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Mendelian Randomization Applied to Neurology: Promises and Challenges

Neurology, 2024-02, Vol.102 (4), p.e209128

2024

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From Preschool Language Skills to Writing in Adolescence: Evidence of Genetic Continuity

Developmental psychology, 2022-07, Vol.58 (7), p.1318-1330

2022

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Genetic inhibition of angiopoietin-like protein-3, lipids, and cardiometabolic risk

European heart journal, 2024-03, Vol.45 (9), p.707-721

2024

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M57 THE IMPACT OF COPY NUMBER VARIANTS ON BRAIN MORPHOMETRY

European neuropsychopharmacology, 2019-10, Vol.29, p.S196-S197

2019

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Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targets

European heart journal open, 2024-05, Vol.4 (3), p.oeae043

2024

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From Preschool Language Skills to Writing in Adolescence: Evidence of Genetic Continuity

CrimRxiv, 2022-04

2022

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Electronic health record-based genome-wide meta-analysis provides insights on the genetic architecture of non-alcoholic fatty liver disease

Polygenic scores differentially predict developmental trajectories of subtypes of social withdrawal in childhood

Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study

Common pitfalls in drug target Mendelian randomization and how to avoid them

Blood Levels of the SMOC1 Hepatokine Are Not Causally Linked with Type 2 Diabetes: A Bidirectional Mendelian Randomization Study

Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease

Large-scale metabolomic profiling and incident non-alcoholic fatty liver disease

Genetic control of body weight by the human brain proteome

Mendelian randomization prioritizes abdominal adiposity as an independent causal factor for liver fat accumulation and cardiometabolic diseases

Impact of loss-of-function in angiopoietin-like 4 on the human phenome

Drug target Mendelian randomization supports apolipoprotein C3-lowering for lipoprotein-lipid levels reductions and cardiovascular diseases prevention

Abstract 15687: Triglyceride Levels and Non-Alcoholic Fatty Liver Disease: A Multivariable Mendelian Randomization Study

Abstract 12056: Angiopoietin-Like Protein 3 Blood Levels and Cardiometabolic Traits and Diseases: A Mendelian Randomization Study

Body Fat Distribution, Fasting Insulin Levels, and Insulin Secretion: A Bidirectional Mendelian Randomization Study

Disentangling the impact of gluteofemoral versus visceral fat accumulation on cardiometabolic health using sex-stratified Mendelian randomization

Impact of loss-of-function in angiopoietin-like 4 on the human phenome

Pancreatitis polygenic risk score is independently associated with all-cause acute pancreatitis risk in the UK Biobank

Proteome-Wide Mendelian Randomization Identifies Causal Links Between Blood Proteins and Acute Pancreatitis

Association of multiple polygenic risk scores with myocardial infarction and atherosclerotic coronary artery lesions in a Canadian population

Mendelian Randomization Applied to Neurology: Promises and Challenges

From Preschool Language Skills to Writing in Adolescence: Evidence of Genetic Continuity

Genetic inhibition of angiopoietin-like protein-3, lipids, and cardiometabolic risk

M57 THE IMPACT OF COPY NUMBER VARIANTS ON BRAIN MORPHOMETRY

Genetic assessment of efficacy and safety profiles of coagulation cascade proteins identifies Factors II and XI as actionable anticoagulant targets

From Preschool Language Skills to Writing in Adolescence: Evidence of Genetic Continuity

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