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Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β -Glucuronidases in Their Disposition

Drug metabolism and disposition, 2017-06, Vol.45 (6), p.657-665

2017

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Pharmacokinetics, Disposition, and Biotransformation of [ 14 C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose

Drug metabolism and disposition, 2021-08, Vol.49 (8), p.619-628

2021

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Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry

Drug metabolism and disposition, 2014-12, Vol.42 (12), p.2023-2032

2014

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug metabolism and disposition, 2013-06, Vol.41 (6), p.1179-1186

2013

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Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans

Drug metabolism and disposition, 2016-01, Vol.44 (1), p.28-39

2016

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The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans

Drug metabolism and disposition, 2008-02, Vol.36 (2), p.386-399

2008

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Predicting Maternal-Fetal Disposition of Fentanyl Following Intravenous and Epidural Administration Using Physiologically Based Pharmacokinetic Modeling

Drug metabolism and disposition, 2021-11, Vol.49 (11), p.1003-1015

2021

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Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV

Drug metabolism and disposition, 2005-04, Vol.33 (4), p.587-595

2005

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Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites

Drug metabolism and disposition, 2015-08, Vol.43 (8), p.1190-1207

2015

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Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor

Drug metabolism and disposition, 2016-08, Vol.44 (8), p.1201-1212

2016

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The Metabolism and Disposition of Brepocitinib in Humans and Characterization of the Formation Mechanism of an Aminopyridine Metabolite

Drug metabolism and disposition, 2024-06, Vol.52 (7), p.690

2024

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The Disposition and Metabolism of Bempedoic Acid, a Potent Inhibitor of ATP Citrate Lyase, in Healthy Human Subjects

Drug metabolism and disposition, 2023-05, Vol.51 (5), p.599-609

2023

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The metabolism and disposition of the oral dipeptidyl peptidase-4 inhibitor, linagliptin, in humans

Drug metabolism and disposition, 2010-04, Vol.38 (4), p.667-678

2010

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Disposition and metabolism of [14C]SB-649868, an orexin 1 and 2 receptor antagonist, in humans

Drug metabolism and disposition, 2011-02, Vol.39 (2), p.215-227

2011

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Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis

Drug metabolism and disposition, 2016-06, Vol.44 (6), p.792-799

2016

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Metabolism and disposition of imatinib mesylate in healthy volunteers

Drug metabolism and disposition, 2005-10, Vol.33 (10), p.1503-1512

2005

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Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme

Drug metabolism and disposition, 2007-09, Vol.35 (9), p.1657-1663

2007

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Metabolism and disposition of [14C]BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor, after oral administration to humans

Drug metabolism and disposition, 2010-11, Vol.38 (11), p.2049-2059

2010

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Disposition and metabolic fate of atomoxetine hydrochloride: the role of CYP2D6 in human disposition and metabolism

Drug metabolism and disposition, 2003-01, Vol.31 (1), p.98-107

2003

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Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state

Drug metabolism and disposition, 2010-05, Vol.38 (5), p.808-816

2010

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Metabolism and disposition of isoflavone conjugated metabolites in humans after ingestion of kinako

Drug metabolism and disposition, 2011-09, Vol.39 (9), p.1762-1767

2011

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The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human

Drug metabolism and disposition, 2003-06, Vol.31 (6), p.731-741

2003

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Disposition and metabolism of the cathepsin K inhibitor odanacatib in humans

Drug metabolism and disposition, 2014-05, Vol.42 (5), p.818-827

2014

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Disposition and metabolism of LY2452473, a selective androgen receptor modulator, in humans

Drug metabolism and disposition, 2012-12, Vol.40 (12), p.2354-2364

2012

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Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes

Drug metabolism and disposition, 2013-02, Vol.41 (2), p.296-304

2013

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Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β -Glucuronidases in Their Disposition

Pharmacokinetics, Disposition, and Biotransformation of [ 14 C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose

Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry

Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans

The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans

Predicting Maternal-Fetal Disposition of Fentanyl Following Intravenous and Epidural Administration Using Physiologically Based Pharmacokinetic Modeling

Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV

Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites

Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor

The Metabolism and Disposition of Brepocitinib in Humans and Characterization of the Formation Mechanism of an Aminopyridine Metabolite

The Disposition and Metabolism of Bempedoic Acid, a Potent Inhibitor of ATP Citrate Lyase, in Healthy Human Subjects

The metabolism and disposition of the oral dipeptidyl peptidase-4 inhibitor, linagliptin, in humans

Disposition and metabolism of [14C]SB-649868, an orexin 1 and 2 receptor antagonist, in humans

Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis

Metabolism and disposition of imatinib mesylate in healthy volunteers

Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme

Metabolism and disposition of [14C]BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor, after oral administration to humans

Disposition and metabolic fate of atomoxetine hydrochloride: the role of CYP2D6 in human disposition and metabolism

Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state

Metabolism and disposition of isoflavone conjugated metabolites in humans after ingestion of kinako

The disposition of voriconazole in mouse, rat, rabbit, guinea pig, dog, and human

Disposition and metabolism of the cathepsin K inhibitor odanacatib in humans

Disposition and metabolism of LY2452473, a selective androgen receptor modulator, in humans

Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: a comparison with adult human hepatocytes

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