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Association between promoter polymorphisms in anterior pharynx-defective-1a and sporadic Alzheimer's disease in the North Chinese Han population

Neuroscience letters, 2009-05, Vol.455 (2), p.101-104

2009

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The azetidine derivative, KHG26792 protects against ATP-induced activation of NFAT and MAPK pathways through P2X7 receptor in microglia

Neurotoxicology (Park Forest South), 2015-12, Vol.51, p.198-206

2015

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Neuroprotective Effect of 3-(Naphthalen-2-Yl(Propoxy)Methyl)Azetidine Hydrochloride on Brain Ischaemia/Reperfusion Injury

Journal of neuroimmune pharmacology, 2017-09, Vol.12 (3), p.447-461

2017

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Functions of the CB1 and CB2 Receptors in Neuroprotection at the Level of the Blood–Brain Barrier

Neuromolecular medicine, 2014-09, Vol.16 (3), p.620-642

2014

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Functional γ-secretase complex assembly in Golgi/ trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and γ-secretase substrates

Neurobiology of disease, 2003-11, Vol.14 (2), p.194-204

2003

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Immune system: A possible nexus between cannabinoids and psychosis

Brain, behavior, and immunity, 2014-08, Vol.40, p.269-282

2014

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Calcium dysregulation in Alzheimer's disease

Neurochemistry international, 2008-03, Vol.52 (4), p.621-633

2008

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Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease

Neurobiology of aging, 2011-03, Vol.32 (3), p.556.e13-556.e23

2011

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Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin

Neurobiology of aging, 2012-02, Vol.33 (2), p.277-285

2012

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Presenilin 1 is involved in the maturation of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1)

Journal of neuroscience research, 2007-01, Vol.85 (1), p.153-165

2007

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Aging of the brain, neurotrophin signaling, and Alzheimer's disease: Is IGF1-R the common culprit?

Neurobiology of aging, 2008-06, Vol.29 (6), p.795-811

Puglielli, Luigi

2008

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Structural biology of presenilin 1 complexes

Molecular neurodegeneration, 2014-12, Vol.9 (1), p.59-59, Article 59

2014

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Identity and function of γ-secretase

Journal of neuroscience research, 2003-11, Vol.74 (3), p.353-360

2003

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The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid

Neurochemical research, 2007-04, Vol.32 (4-5), p.609-623

2007

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Pathological activity of familial Alzheimer’s disease-associated mutant presenilin can be executed by six different γ-secretase complexes

Neurobiology of disease, 2007-07, Vol.27 (1), p.102-107

2007

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Overexpression of calsenilin enhances γ-secretase activity

Neuroscience letters, 2005-04, Vol.378 (1), p.59-64

2005

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Conserved “PAL” sequence in presenilins is essential for γ-secretase activity, but not required for formation or stabilization of γ-secretase complexes

Neurobiology of disease, 2004-04, Vol.15 (3), p.654-666

2004

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Localization of presenilin–nicastrin complexes and γ‐secretase activity to the trans‐Golgi network

Journal of neurochemistry, 2003-03, Vol.84 (5), p.1143-1153

2003

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TMP21 degradation is mediated by the ubiquitin-proteasome pathway

The European journal of neuroscience, 2008-11, Vol.28 (10), p.1980-1988

2008

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Loss of nicastrin elicits an apoptotic phenotype in mouse embryos

Brain research, 2006-05, Vol.1086 (1), p.76-84

2006

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Presenilin endoproteolysis mediated by an aspartyl protease activity pharmacologically distinct from γ‐secretase

Journal of neurochemistry, 2003-06, Vol.85 (6), p.1563-1574

2003

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Genetic association between polymorphisms of Pen2 gene and late onset Alzheimer's disease in the North Chinese population

Brain research, 2007-04, Vol.1141, p.10-14

2007

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Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain

Neuroscience, 2004, Vol.129 (3), p.615-628

2004

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New players in old amyloid precursor protein‐processing pathways

International journal of developmental neuroscience, 2004-11, Vol.22 (7), p.467-474

Rossner, Steffen

2004

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APP processing enzymes (secretases) as therapeutic targets: insights from the use of transgenics (Tgs) and transfected cells

Neurochemical research, 2003-07, Vol.28 (7), p.1049-1062

2003

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Association between promoter polymorphisms in anterior pharynx-defective-1a and sporadic Alzheimer's disease in the North Chinese Han population

The azetidine derivative, KHG26792 protects against ATP-induced activation of NFAT and MAPK pathways through P2X7 receptor in microglia

Neuroprotective Effect of 3-(Naphthalen-2-Yl(Propoxy)Methyl)Azetidine Hydrochloride on Brain Ischaemia/Reperfusion Injury

Functions of the CB1 and CB2 Receptors in Neuroprotection at the Level of the Blood–Brain Barrier

Functional γ-secretase complex assembly in Golgi/ trans-Golgi network: interactions among presenilin, nicastrin, Aph1, Pen-2, and γ-secretase substrates

Immune system: A possible nexus between cannabinoids and psychosis

Calcium dysregulation in Alzheimer's disease

Amyloid precursor protein (APP) processing genes and cerebrospinal fluid APP cleavage product levels in Alzheimer's disease

Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin

Presenilin 1 is involved in the maturation of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1)

Aging of the brain, neurotrophin signaling, and Alzheimer's disease: Is IGF1-R the common culprit?

Structural biology of presenilin 1 complexes

Identity and function of γ-secretase

The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloid

Pathological activity of familial Alzheimer’s disease-associated mutant presenilin can be executed by six different γ-secretase complexes

Overexpression of calsenilin enhances γ-secretase activity

Conserved “PAL” sequence in presenilins is essential for γ-secretase activity, but not required for formation or stabilization of γ-secretase complexes

Localization of presenilin–nicastrin complexes and γ‐secretase activity to the trans‐Golgi network

TMP21 degradation is mediated by the ubiquitin-proteasome pathway

Loss of nicastrin elicits an apoptotic phenotype in mouse embryos

Presenilin endoproteolysis mediated by an aspartyl protease activity pharmacologically distinct from γ‐secretase

Genetic association between polymorphisms of Pen2 gene and late onset Alzheimer's disease in the North Chinese population

Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain

New players in old amyloid precursor protein‐processing pathways

APP processing enzymes (secretases) as therapeutic targets: insights from the use of transgenics (Tgs) and transfected cells

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