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Deciphering actin remodelling in immune cells through the prism of actin-related inborn errors of immunity

European journal of cell biology, 2023-03, Vol.102 (1), p.151283-151283, Article 151283

2023

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Molecular Tuning of Actin Dynamics in Leukocyte Migration as Revealed by Immune-Related Actinopathies

Frontiers in immunology, 2021-11, Vol.12, p.750537-750537

2021

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Actin Dynamics at the T Cell Synapse as Revealed by Immune-Related Actinopathies

Frontiers in cell and developmental biology, 2021-06, Vol.9, p.665519-665519

2021

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Lymphocyte migration and retention properties affected by ibrutinib in chronic lymphocytic leukemia

Haematologica (Roma), 2024-03, Vol.109 (3), p.809-823

2024

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LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity

Nature communications, 2024-01, Vol.15 (1), p.407-407, Article 407

2024

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Computational modelling of cell motility modes emerging from cell-matrix adhesion dynamics

PLoS computational biology, 2022-02, Vol.18 (2), p.e1009156-e1009156

2022

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initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.6073-6078

2013

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Mutations affecting the actin regulator WD repeat–containing protein 1 lead to aberrant lymphoid immunity

Journal of allergy and clinical immunology, 2018-11, Vol.142 (5), p.1589-1604.e11

2018

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Molecular Tuning of Filamin A Activities in the Context of Adhesion and Migration

Frontiers in cell and developmental biology, 2020-11, Vol.8, p.591323-591323

2020

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Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells

Cell reports (Cambridge), 2024-03, Vol.43 (3), p.113853-113853, Article 113853

2024

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The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse

Cell reports (Cambridge), 2018-01, Vol.22 (4), p.979-991

2018

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EVER proteins, key elements of the natural anti-human papillomavirus barrier, are regulated upon T-cell activation

PloS one, 2012-06, Vol.7 (6), p.e39995-e39995

2012

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Population Pharmacokinetics of Ibrutinib and Its Dihydrodiol Metabolite in Patients with Lymphoid Malignancies

Clinical pharmacokinetics, 2020-09, Vol.59 (9), p.1171-1183

2020

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Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation

Haematologica (Roma), 2020-10, Vol.105 (10), p.e488

2020

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WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells

The Journal of experimental medicine, 2007-02, Vol.204 (2), p.369-380

2007

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T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency

Blood, 2018-11, Vol.132 (22), p.2362-2374

2018

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Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing

Cell reports (Cambridge), 2015-06, Vol.11 (9), p.1474-1485

2015

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The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling

Haematologica (Roma), 2011-10, Vol.96 (10), p.1415-1423

2011

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Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8 + T Cells in Elderly Humans

The Journal of immunology (1950), 2022-02, Vol.208 (3), p.562-570

2022

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CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia

Cancer research (Chicago, Ill.), 2013-06, Vol.73 (11), p.3412-3424

2013

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Morphological profiling of human T and NK lymphocytes by high-content cell imaging

Cell reports (Cambridge), 2021-07, Vol.36 (1), p.109318-109318, Article 109318

2021

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RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics

Nature immunology, 2016-12, Vol.17 (12), p.1352-1360

2016

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Mechanisms underlying skin inflammation of DOCK8 deficiency

Journal of allergy and clinical immunology, 2024-07, Vol.154 (1), p.88-90

2024

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R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome

Journal of allergy and clinical immunology, 2018-07, Vol.142 (1), p.219-234

2018

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Deciphering actin remodelling in immune cells through the prism of actin-related inborn errors of immunity

Molecular Tuning of Actin Dynamics in Leukocyte Migration as Revealed by Immune-Related Actinopathies

Actin Dynamics at the T Cell Synapse as Revealed by Immune-Related Actinopathies

Lymphocyte migration and retention properties affected by ibrutinib in chronic lymphocytic leukemia

LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity

Computational modelling of cell motility modes emerging from cell-matrix adhesion dynamics

initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse

Mutations affecting the actin regulator WD repeat–containing protein 1 lead to aberrant lymphoid immunity

Molecular Tuning of Filamin A Activities in the Context of Adhesion and Migration

Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse

EVER proteins, key elements of the natural anti-human papillomavirus barrier, are regulated upon T-cell activation

Population Pharmacokinetics of Ibrutinib and Its Dihydrodiol Metabolite in Patients with Lymphoid Malignancies

Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells

T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency

Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing

The Wiskott-Aldrich syndrome protein permits assembly of a focused immunological synapse enabling sustained T-cell receptor signaling

Altered Basal Lipid Metabolism Underlies the Functional Impairment of Naive CD8 + T Cells in Elderly Humans

CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia

Morphological profiling of human T and NK lymphocytes by high-content cell imaging

RASGRP1 deficiency causes immunodeficiency with impaired cytoskeletal dynamics

Mechanisms underlying skin inflammation of DOCK8 deficiency

R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome

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