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Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial

PloS one, 2017-07, Vol.12 (7), p.e0180762-e0180762

2017

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Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1825-E1832

2017

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A potent Lassa virus antiviral targets an arenavirus virulence determinant

PLoS pathogens, 2018-12, Vol.14 (12), p.e1007439-e1007439

2018

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Inhibition of alpha 9 alpha 10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1825-E1825

2017

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Kv1.3 blockade by ShK186 modulates CD4+ effector memory T-cell activity of patients with granulomatosis with polyangiitis

Rheumatology (Oxford, England), 2024-01, Vol.63 (1), p.198-208

2024

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Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway

Journal of virology, 2016-03, Vol.90 (5), p.2372-2387

2016

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1357 CD27 is a new promising T cell co-stimulatory target for the cancer immunotherapy – development and selection of a lead anti-CD27 agonist antibody

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1511-A1511

2023

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Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

Toxicon (Oxford), 2012-03, Vol.59 (4), p.529-546

2012

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A highly potent anti-VISTA antibody KVA12123 - a new immune checkpoint inhibitor and a promising therapy against poorly immunogenic tumors

Frontiers in immunology, 2023-12, Vol.14, p.1311658

2023

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Extracellular 2′-5′ Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity

Journal of Virology, 2010-11, Vol.84 (22), p.11898-11904

2010

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780 VISTA-101 – A phase 1/2 clinical trial of KVA12123, an engineered IgG1 targeting VISTA, alone and in combination with pembrolizumab in advanced solid tumors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A877-A877

2023

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Kv1.3 channel‐blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

The FASEB journal, 2014-09, Vol.28 (9), p.3952-3964

2014

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A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response

Vaccine, 2017-04, Vol.35 (15), p.1964-1971

2017

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Isoflavone Agonists of IRF-3 Dependent Signaling Have Antiviral Activity against RNA Viruses

Journal of Virology, 2012-07, Vol.86 (13), p.7334-7344

2012

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Corrigendum: A highly potent anti-VISTA antibody KVA12123 - a new immune checkpoint inhibitor and a promising therapy against poorly immunogenic tumors

Frontiers in immunology, 2024, Vol.15, p.1365240-1365240

2024

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Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease

The Journal of pharmacology and experimental therapeutics, 2012-09, Vol.342 (3), p.642-653

2012

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Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.E2239-E2248

2013

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Kv1.3 Channel Blockade Modulates the Effector Function of B Cells in Granulomatosis with Polyangiitis

Frontiers in immunology, 2017-09, Vol.8, p.1205-1205

2017

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Genomics Hepatitis C virus gets personal

Nature (London), 2009-09, Vol.461 (7262), p.357-358

2009

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879 A promising cancer immunotherapy target: novel fully human agonist antibodies against the human T-cell costimulatory receptor CD27

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A921-A921

2021

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VISTA a Potential New Immuno-Oncology Target in Acute Myeloid Leukemia

Blood, 2023-11, Vol.142 (Supplement 1), p.5965-5965

2023

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Hepatitis C virus gets personal

Nature (London), 2009-09, Vol.461 (7262), p.357-358

2009

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High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations

BMC genomics, 2007-01, Vol.8 (1), p.28-28, Article 28

2007

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Abstract B034: CD27 is a new promising T cell co-stimulatory target for cancer immunotherapy

Cancer immunology research, 2023-12, Vol.11 (12_Supplement), p.B034-B034

2023

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Distinct gene expression profiles in peripheral blood mononuclear cells from patients infected with vaccinia virus, yellow fever 17D virus, or upper respiratory infections

Vaccine, 2007-08, Vol.25 (35), p.6458-6473

2007

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Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial

Inhibition of α9α10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

A potent Lassa virus antiviral targets an arenavirus virulence determinant

Inhibition of alpha 9 alpha 10 nicotinic acetylcholine receptors prevents chemotherapy-induced neuropathic pain

Kv1.3 blockade by ShK186 modulates CD4+ effector memory T-cell activity of patients with granulomatosis with polyangiitis

Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway

1357 CD27 is a new promising T cell co-stimulatory target for the cancer immunotherapy – development and selection of a lead anti-CD27 agonist antibody

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

A highly potent anti-VISTA antibody KVA12123 - a new immune checkpoint inhibitor and a promising therapy against poorly immunogenic tumors

Extracellular 2′-5′ Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity

780 VISTA-101 – A phase 1/2 clinical trial of KVA12123, an engineered IgG1 targeting VISTA, alone and in combination with pembrolizumab in advanced solid tumors

Kv1.3 channel‐blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases

A small-molecule IRF3 agonist functions as an influenza vaccine adjuvant by modulating the antiviral immune response

Isoflavone Agonists of IRF-3 Dependent Signaling Have Antiviral Activity against RNA Viruses

Corrigendum: A highly potent anti-VISTA antibody KVA12123 - a new immune checkpoint inhibitor and a promising therapy against poorly immunogenic tumors

Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease

Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance

Kv1.3 Channel Blockade Modulates the Effector Function of B Cells in Granulomatosis with Polyangiitis

Genomics Hepatitis C virus gets personal

879 A promising cancer immunotherapy target: novel fully human agonist antibodies against the human T-cell costimulatory receptor CD27

VISTA a Potential New Immuno-Oncology Target in Acute Myeloid Leukemia

Hepatitis C virus gets personal

High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations

Abstract B034: CD27 is a new promising T cell co-stimulatory target for cancer immunotherapy

Distinct gene expression profiles in peripheral blood mononuclear cells from patients infected with vaccinia virus, yellow fever 17D virus, or upper respiratory infections

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