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N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model

Bioorganic & medicinal chemistry, 2018-10, Vol.26 (18), p.5169-5180

2018

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Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

Bioorganic & medicinal chemistry, 2020-04, Vol.28 (7), p.115403-115403, Article 115403

2020

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Recent developments and biological activities of thiazolidinone derivatives: A review

Bioorganic & medicinal chemistry, 2012-06, Vol.20 (11), p.3378-3395

2012

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Anticancer profile of newly synthesized BRAF inhibitors possess 5-(pyrimidin-4-yl)imidazo[2,1-b]thiazole scaffold

Bioorganic & medicinal chemistry, 2019-05, Vol.27 (10), p.2041-2051

2019

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Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors

Bioorganic & medicinal chemistry, 2016-03, Vol.24 (6), p.1298-1307

2016

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Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation

Bioorganic & medicinal chemistry, 2011-05, Vol.19 (10), p.3135-3140

2011

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Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors

Bioorganic & medicinal chemistry, 2021-09, Vol.46, p.116367-116367, Article 116367

2021

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Studies on non-steroidal inhibitors of aromatase enzyme; 4-(aryl/heteroaryl)-2-(pyrimidin-2-yl)thiazole derivatives

Bioorganic & medicinal chemistry, 2018-05, Vol.26 (8), p.1986-1995

2018

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Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies

Bioorganic & medicinal chemistry, 2015-05, Vol.23 (10), p.2518-2528

2015

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Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential

Bioorganic & medicinal chemistry, 2021-11, Vol.50, p.116453, Article 116453

2021

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Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs

Bioorganic & medicinal chemistry, 2010, Vol.18 (1), p.426-432

2010

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Structure-activity relationship studies in substituted sulfamoyl benzamidothiazoles that prolong NF-κB activation

Bioorganic & medicinal chemistry, 2021-08, Vol.43, p.116242-116242, Article 116242

2021

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Synthesis of new spirooxindole-pyrrolothiazole derivatives: Anti-cancer activity and molecular docking

Bioorganic & medicinal chemistry, 2017-02, Vol.25 (4), p.1514-1523

2017

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Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents

Bioorganic & medicinal chemistry, 2009-01, Vol.17 (2), p.882-895

2009

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Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115188, Article 115188

2020

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Synthesis and Pin1 inhibitory activity of thiazole derivatives

Bioorganic & medicinal chemistry, 2016-11, Vol.24 (22), p.5911-5920

2016

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Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors

Bioorganic & medicinal chemistry, 2021-12, Vol.51, p.116507-116507, Article 116507

2021

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Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds

Bioorganic & medicinal chemistry, 2012-04, Vol.20 (7), p.2214-2220

2012

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Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4)

Bioorganic & medicinal chemistry, 2017-02, Vol.25 (3), p.1042-1056

2017

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Synthesis of PF-6870961, a major hydroxy metabolite of the novel ghrelin receptor inverse agonist PF-5190457

Bioorganic & medicinal chemistry, 2021-11, Vol.50, p.116465, Article 116465

2021

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Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors

Bioorganic & medicinal chemistry, 2016-03, Vol.24 (5), p.1050-1062

2016

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Synthesis and antimicrobial activity of novel 2-thiazolylimino-5-arylidene-4-thiazolidinones

Bioorganic & medicinal chemistry, 2006-06, Vol.14 (11), p.3859-3864

2006

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Synthesis and biological evaluation of 2-substituted-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents

Bioorganic & medicinal chemistry, 2012-12, Vol.20 (24), p.7083-7094

2012

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The multifunctional dopamine D 2 /D 3 receptor agonists also possess inhibitory activity against the full-length tau441 protein aggregation

Bioorganic & medicinal chemistry, 2020-09, Vol.28 (18), p.115667

2020

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Structure–activity relationships of 2-aminothiazoles effective against Mycobacterium tuberculosis

Bioorganic & medicinal chemistry, 2013-11, Vol.21 (21), p.6385-6397

2013

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N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model

Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes

Recent developments and biological activities of thiazolidinone derivatives: A review

Anticancer profile of newly synthesized BRAF inhibitors possess 5-(pyrimidin-4-yl)imidazo[2,1-b]thiazole scaffold

Design, synthesis and biological evaluation of imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole derivatives as Mycobacterium tuberculosis pantothenate synthetase inhibitors

Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation

Harmine-inspired design and synthesis of benzo[d]imidazo[2,1-b]thiazole derivatives bearing 1,3,4-oxadiazole moiety as potential tumor suppressors

Studies on non-steroidal inhibitors of aromatase enzyme; 4-(aryl/heteroaryl)-2-(pyrimidin-2-yl)thiazole derivatives

Novel thiazolo[3,2-b]-1,2,4-triazoles derived from naproxen with analgesic/anti-inflammatory properties: Synthesis, biological evaluation and molecular modeling studies

Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential

Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs

Structure-activity relationship studies in substituted sulfamoyl benzamidothiazoles that prolong NF-κB activation

Synthesis of new spirooxindole-pyrrolothiazole derivatives: Anti-cancer activity and molecular docking

Design and synthesis of some thiazolyl and thiadiazolyl derivatives of antipyrine as potential non-acidic anti-inflammatory, analgesic and antimicrobial agents

Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase

Synthesis and Pin1 inhibitory activity of thiazole derivatives

Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors

Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds

Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4)

Synthesis of PF-6870961, a major hydroxy metabolite of the novel ghrelin receptor inverse agonist PF-5190457

Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors

Synthesis and antimicrobial activity of novel 2-thiazolylimino-5-arylidene-4-thiazolidinones

Synthesis and biological evaluation of 2-substituted-4-(3′,4′,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents

The multifunctional dopamine D 2 /D 3 receptor agonists also possess inhibitory activity against the full-length tau441 protein aggregation

Structure–activity relationships of 2-aminothiazoles effective against Mycobacterium tuberculosis

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