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CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

1, 2022

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CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

Cell stem cell, 2020-04, Vol.26 (4), p.503-510.e7

2020

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A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9

Cell, 2019-05, Vol.177 (4), p.1067-1079.e19

2019

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Principles, Applications, and Biosafety of Plant Genome Editing Using CRISPR-Cas9

Frontiers in plant science, 2020-02, Vol.11, p.56-56

2020

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A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

Cell reports (Cambridge), 2018-02, Vol.22 (9), p.2227-2235

2018

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Efficient in planta gene targeting in tomato using geminiviral replicons and the CRISPR/Cas9 system

The Plant journal : for cell and molecular biology, 2018-07, Vol.95 (1), p.5-16

2018

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Cas9-expressing chickens and pigs as resources for genome editing in livestock

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (10), p.1

2021

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ARGOS8 variants generated by CRISPR‐Cas9 improve maize grain yield under field drought stress conditions

Plant biotechnology journal, 2017-02, Vol.15 (2), p.207-216

2017

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Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

Molecular cell, 2019-02, Vol.73 (3), p.601-610.e5

2019

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Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

Angewandte Chemie (International ed.), 2015-10, Vol.54 (41), p.12029-12033

International ed. in English, 2015

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Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse

Developmental biology, 2016-10, Vol.418 (1), p.1-9

2016

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One‐step generation of mice with gene editing by Tol2 transposon‐dependent gRNA delivery

FEBS letters, 2023-04, Vol.597 (7), p.975-984

2023

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Valproic Acid Thermally Destabilizes and Inhibits SpyCas9 Activity

Molecular therapy, 2020-12, Vol.28 (12), p.2635-2641

Cheng, Xinlai

2020

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Gene editing of the wheat homologs of TONNEAU1‐recruiting motif encoding gene affects grain shape and weight in wheat

The Plant journal : for cell and molecular biology, 2019-10, Vol.100 (2), p.251-264

2019

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CRISPR/Cas9 technology as a potent molecular tool for gene therapy

Journal of cellular physiology, 2019-08, Vol.234 (8), p.12267-12277

2019

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Generation of a multiplex mutagenesis population via pooled CRISPR‐Cas9 in soya bean

Plant biotechnology journal, 2020-03, Vol.18 (3), p.721-731

2020

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CRISPR/Cas9-based epigenome editing: An overview of dCas9-based tools with special emphasis on off-target activity

Methods (San Diego, Calif.), 2019-07, Vol.164-165, p.109-119

2019

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Genome Editing: Targeting Susceptibility Genes for Plant Disease Resistance

Trends in biotechnology (Regular ed.), 2018-09, Vol.36 (9), p.898-906

2018

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Selective gene dosage by CRISPR‐Cas9 genome editing in hexaploid Camelina sativa

Plant biotechnology journal, 2017-06, Vol.15 (6), p.729-739

2017

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Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish

Developmental cell, 2019-12, Vol.51 (5), p.645-657.e4

2019

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Insert, remove or replace: A highly advanced genome editing system using CRISPR/Cas9

Biochimica et biophysica acta, 2016-09, Vol.1863 (9), p.2333-2344

2016

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Step‐Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR‐Cas9 Genome Editing

Stem cells (Dayton, Ohio), 2019-01, Vol.37 (1), p.65-76

2019

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CRISPR/Cas System: Recent Advances and Future Prospects for Genome Editing

Trends in plant science, 2019-12, Vol.24 (12), p.1102-1125

2019

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Genome editing prospects for heat stress tolerance in cereal crops

Plant physiology and biochemistry, 2024-10, Vol.215, p.108989, Article 108989

2024

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Efficient Cas9 multiplex editing using unspaced sgRNA arrays engineering in a Potato virus X vector

The Plant journal : for cell and molecular biology, 2021-04, Vol.106 (2), p.555-565

2021

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1 – 25 von 2.152

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CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank

A High-Throughput Platform to Identify Small-Molecule Inhibitors of CRISPR-Cas9

Principles, Applications, and Biosafety of Plant Genome Editing Using CRISPR-Cas9

A Single Administration of CRISPR/Cas9 Lipid Nanoparticles Achieves Robust and Persistent In Vivo Genome Editing

Efficient in planta gene targeting in tomato using geminiviral replicons and the CRISPR/Cas9 system

Cas9-expressing chickens and pigs as resources for genome editing in livestock

ARGOS8 variants generated by CRISPR‐Cas9 improve maize grain yield under field drought stress conditions

Temperature-Responsive Competitive Inhibition of CRISPR-Cas9

Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing

Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse

One‐step generation of mice with gene editing by Tol2 transposon‐dependent gRNA delivery

Valproic Acid Thermally Destabilizes and Inhibits SpyCas9 Activity

Gene editing of the wheat homologs of TONNEAU1‐recruiting motif encoding gene affects grain shape and weight in wheat

CRISPR/Cas9 technology as a potent molecular tool for gene therapy

Generation of a multiplex mutagenesis population via pooled CRISPR‐Cas9 in soya bean

CRISPR/Cas9-based epigenome editing: An overview of dCas9-based tools with special emphasis on off-target activity

Genome Editing: Targeting Susceptibility Genes for Plant Disease Resistance

Selective gene dosage by CRISPR‐Cas9 genome editing in hexaploid Camelina sativa

Highly Efficient CRISPR-Cas9-Based Methods for Generating Deletion Mutations and F0 Embryos that Lack Gene Function in Zebrafish

Insert, remove or replace: A highly advanced genome editing system using CRISPR/Cas9

Step‐Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR‐Cas9 Genome Editing

CRISPR/Cas System: Recent Advances and Future Prospects for Genome Editing

Genome editing prospects for heat stress tolerance in cereal crops

Efficient Cas9 multiplex editing using unspaced sgRNA arrays engineering in a Potato virus X vector

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